Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Pablo, Bifani"'
Detection of florfenicol resistance in opportunistic Acinetobacter spp. infections in rural Thailand
Autor:
Bernice Siu Yan Tan, Lalit Mohan, Wanitda Watthanaworawit, Thundon Ngamprasertchai, Francois H. Nosten, Clare Ling, Pablo Bifani
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Florfenicol (Ff) is an antimicrobial agent belonging to the class amphenicol used for the treatment of bacterial infections in livestock, poultry, and aquaculture (animal farming). It inhibits protein synthesis. Ff is an analog of chloramphenicol, an
Externí odkaz:
https://doaj.org/article/088eb02a020440feb61b0471dcd6a76f
Autor:
Teck-Hui Teo, Nurul N. Ayuni, Michelle Yin, Jun Hao Liew, Jason Q. Chen, Natalia Kurepina, Ravisankar Rajarethinam, Barry N. Kreiswirth, Liang Chen, Pablo Bifani
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108875- (2024)
Summary: Klebsiella pneumoniae (Kp) infection is an important healthcare concern. The ST258 classical (c)Kp strain is dominant in hospital-acquired infections in North America and Europe, while ST23 hypervirulent (hv)Kp prevails in community-acquired
Externí odkaz:
https://doaj.org/article/b9f9486cddbb4a01860c5cd5a53c92f6
Autor:
Shivankari Krishnananthasivam, Hao Li, Rania Bouzeyen, Bhuvaneshwari Shunmuganathan, Kiren Purushotorman, Xinlei Liao, Fengjiao Du, Claudia Guldager Kring Friis, Felicity Crawshay-Williams, Low Heng Boon, Qian Xinlei, Conrad En Zuo Chan, Radoslaw Sobota, Mary Kozma, Valeria Barcelli, Guirong Wang, Hairong Huang, Andreas Floto, Pablo Bifani, Babak Javid, Paul A. MacAry
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract Tuberculosis (TB) is an airborne disease caused by Mycobacterium tuberculosis (Mtb). Whilst a functional role for humoral immunity in Mtb protection remains poorly defined, previous studies have suggested that antibodies can contribute towar
Externí odkaz:
https://doaj.org/article/b24451097c804d2ba5f67b2d5c67eea3
Autor:
Swaleeha Jaan Abdullah, Bernice Tan Siu Yan, Nithya Palanivelu, Vidhya Bharathi Dhanabal, Juan Pablo Bifani, Surajit Bhattacharjya
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2122 (2024)
Currently, viable antibiotics available to mitigate infections caused by drug-resistant Gram-negative bacteria are highly limited. Thanatin, a 21-residue-long insect-derived antimicrobial peptide (AMP), is a promising lead molecule for the potential
Externí odkaz:
https://doaj.org/article/1eab19a6ae4c469ca1e3b1f12eb72d86
Autor:
Shivankari Krishnananthasivam, Hao Li, Rania Bouzeyen, Bhuvaneshwari Shunmuganathan, Kiren Purushotorman, Xinlei Liao, Fengjiao Du, Claudia Guldager Kring Friis, Felicity Crawshay-Williams, Low Heng Boon, Qian Xinlei, Conrad En Zuo Chan, Radoslaw Sobota, Mary Kozma, Valeria Barcelli, Guirong Wang, Hairong Huang, Andreas Floto, Pablo Bifani, Babak Javid, Paul A. MacAry
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/61f8a2d516d048cba436c52a464a71b5
Autor:
Steven P. Maher, Amélie Vantaux, Victor Chaumeau, Adeline C. Y. Chua, Caitlin A. Cooper, Chiara Andolina, Julie Péneau, Mélanie Rouillier, Zaira Rizopoulos, Sivchheng Phal, Eakpor Piv, Chantrea Vong, Sreyvouch Phen, Chansophea Chhin, Baura Tat, Sivkeng Ouk, Bros Doeurk, Saorin Kim, Sangrawee Suriyakan, Praphan Kittiphanakun, Nana Akua Awuku, Amy J. Conway, Rays H. Y. Jiang, Bruce Russell, Pablo Bifani, Brice Campo, François Nosten, Benoît Witkowski, Dennis E. Kyle
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Improved control of Plasmodium vivax malaria can be achieved with the discovery of new antimalarials with radical cure efficacy, including prevention of relapse caused by hypnozoites residing in the liver of patients. We screened several com
Externí odkaz:
https://doaj.org/article/82bd81cce09f483dac02985c053a9b50
Autor:
Adeline C. Y. Chua, Jessica Jie Ying Ong, Benoit Malleret, Rossarin Suwanarusk, Varakorn Kosaisavee, Anne-Marie Zeeman, Caitlin A. Cooper, Kevin S. W. Tan, Rou Zhang, Bee Huat Tan, Siti Nurdiana Abas, Andy Yip, Anne Elliot, Chester J. Joyner, Jee Sun Cho, Kate Breyer, Szczepan Baran, Amber Lange, Steven P. Maher, François Nosten, Christophe Bodenreider, Bryan K. S. Yeung, Dominique Mazier, Mary R. Galinski, Nathalie Dereuddre-Bosquet, Roger Le Grand, Clemens H. M. Kocken, Laurent Rénia, Dennis E. Kyle, Thierry T. Diagana, Georges Snounou, Bruce Russell, Pablo Bifani
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Present understanding of Plasmodium vivax biology is hampered by its inability to grow in vitro. Here, the authors developed an in vitro culture of its simian counterpart, P. cynomolgi, which shares morphological and phenotypic similarities with P. v
Externí odkaz:
https://doaj.org/article/68f08622b7b941e08fb8d5ecab44264a
Autor:
Kurt E Ward, Peter Christensen, Annie Racklyeft, Satish K Dhingra, Adeline C Y Chua, Caroline Remmert, Rossarin Suwanarusk, Jessica Matheson, Michael J Blackman, Osamu Kaneko, Dennis E Kyle, Marcus C S Lee, Robert W Moon, Georges Snounou, Laurent Rénia, David A Fidock, Bruce Russell, Pablo Bifani
Publikováno v:
The Journal of Infectious Diseases. 227:1121-1126
The lack of a long-term in vitro culture method has severely restricted the study of Plasmodium vivax, in part because it limits genetic manipulation and reverse genetics. We used the recently optimized Plasmodium cynomolgi Berok in vitro culture mod
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 7, Iss 1, Pp 1-3 (2018)
Abstract Treating M. abscessus infection is challenging due to the potent β-lactamase BlaMab (Beta-lactamase of M. abscessus ). Avibactam is a non-β-lactam, β-lactamase inhibitor shown to inhibit BlaMab. We tested whether avibactem can render pipe
Externí odkaz:
https://doaj.org/article/c17989bf969e4e47956c3684f2b35a96
Autor:
Devendra Kumar Gupta, Laurent Dembele, Annemarie Voorberg-van der Wel, Guglielmo Roma, Andy Yip, Vorada Chuenchob, Niwat Kangwanrangsan, Tomoko Ishino, Ashley M Vaughan, Stefan H Kappe, Erika L Flannery, Jetsumon Sattabongkot, Sebastian Mikolajczak, Pablo Bifani, Clemens HM Kocken, Thierry Tidiane Diagana
Publikováno v:
eLife, Vol 8 (2019)
Plasmodium vivax hypnozoites persist in the liver, cause malaria relapse and represent a major challenge to malaria elimination. Our previous transcriptomic study provided a novel molecular framework to enhance our understanding of the hypnozoite bio
Externí odkaz:
https://doaj.org/article/540dc51dd9114b2692252ce1dd245d8e