An integrated transcriptomic cell atlas of human neural organoids.

Autor: He Z; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland. zhisong.he@bsse.ethz.ch., Dony L; Institute of Computational Biology, Computational Health Center, Helmholtz Munich, Neuherberg, Germany.; Department Genes and Environment, Max Planck Institute of Psychiatry, Munich, Germany.; International Max Planck Research School for Translational Psychiatry (IMPRS-TP), Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany., Fleck JS; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Szałata A; Institute of Computational Biology, Computational Health Center, Helmholtz Munich, Neuherberg, Germany.; School of Computation, Information, and Technology, Technical University of Munich, Munich, Germany., Li KX; Institute of Computational Biology, Computational Health Center, Helmholtz Munich, Neuherberg, Germany.; Department Genes and Environment, Max Planck Institute of Psychiatry, Munich, Germany., Slišković I; Institute of Computational Biology, Computational Health Center, Helmholtz Munich, Neuherberg, Germany.; Department Genes and Environment, Max Planck Institute of Psychiatry, Munich, Germany.; International Max Planck Research School for Translational Psychiatry (IMPRS-TP), Munich, Germany., Lin HC; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Santel M; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Atamian A; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Quadrato G; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Sun J; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Pașca SP; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis Program, Wu Tsai Neurosciences Institute and Bio-X, Stanford, CA, USA., Camp JG; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland. jarrettgrayson.camp@unibas.ch.; Biozentrum, University of Basel, Basel, Switzerland. jarrettgrayson.camp@unibas.ch., Theis FJ; Institute of Computational Biology, Computational Health Center, Helmholtz Munich, Neuherberg, Germany. fabian.theis@helmholtz-munich.de.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany. fabian.theis@helmholtz-munich.de.; School of Computation, Information, and Technology, Technical University of Munich, Munich, Germany. fabian.theis@helmholtz-munich.de., Treutlein B; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland. barbara.treutlein@bsse.ethz.ch.

Publikováno v: Nature [Nature] 2024 Nov; Vol. 635 (8039), pp. 690-698. Date of Electronic Publication: 2024 Nov 20.

Assembloid model to study loop circuits of the human nervous system.

Autor: Miura Y, Kim JI, Jurjuț O, Kelley KW, Yang X, Chen X, Thete MV, Revah O, Cui B, Pachitariu M, Pașca SP

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 14. Date of Electronic Publication: 2024 Oct 14.

Antisense oligonucleotide therapeutic approach for Timothy syndrome.

Autor: Chen X; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute & Bio-X, Stanford University, Stanford, CA, USA., Birey F; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute & Bio-X, Stanford University, Stanford, CA, USA.; Department of Human Genetics, Emory University, Atlanta, GA, USA., Li MY; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute & Bio-X, Stanford University, Stanford, CA, USA., Revah O; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute & Bio-X, Stanford University, Stanford, CA, USA., Levy R; Department of Neurology, Division of Child Neurology, Stanford University, Stanford, CA, USA., Thete MV; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute & Bio-X, Stanford University, Stanford, CA, USA., Reis N; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute & Bio-X, Stanford University, Stanford, CA, USA., Kaganovsky K; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute & Bio-X, Stanford University, Stanford, CA, USA., Onesto M; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute & Bio-X, Stanford University, Stanford, CA, USA., Sakai N; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA., Hudacova Z; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA., Hao J; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute & Bio-X, Stanford University, Stanford, CA, USA., Meng X; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute & Bio-X, Stanford University, Stanford, CA, USA., Nishino S; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA., Huguenard J; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Pașca SP; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA. spasca@stanford.edu.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute & Bio-X, Stanford University, Stanford, CA, USA. spasca@stanford.edu.

Publikováno v: Nature [Nature] 2024 Apr; Vol. 628 (8009), pp. 818-825. Date of Electronic Publication: 2024 Apr 24.

Constructing human neural circuits in living systems by transplantation.

Autor: Pașca SP; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA; Stanford Brain Organogenesis Program, Wu Tsai Neurosciences Institute and Bio-X, Stanford, CA, USA. Electronic address: spasca@stanford.edu.

Publikováno v: Cell [Cell] 2024 Jan 04; Vol. 187 (1), pp. 8-13.

Spatially controlled construction of assembloids using bioprinting.

Autor: Roth JG; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute & Bio-X, Stanford University, Stanford, CA, USA.; Complex in Vitro Systems, Safety Assessment, Genentech Inc., South San Francisco, CA, USA., Brunel LG; Department of Chemical Engineering, Stanford University, Stanford, CA, USA., Huang MS; Department of Chemical Engineering, Stanford University, Stanford, CA, USA., Liu Y; Department of Materials Science and Engineering, Stanford University, Stanford, CA, USA., Cai B; Department of Materials Science and Engineering, Stanford University, Stanford, CA, USA., Sinha S; Department of Bioengineering, Stanford University, Stanford, CA, USA., Yang F; Department of Bioengineering, Stanford University, Stanford, CA, USA.; Department of Orthopedic Surgery, Stanford University School of Medicine, Stanford, CA, USA., Pașca SP; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute & Bio-X, Stanford University, Stanford, CA, USA.; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA., Shin S; Department of Materials Science and Engineering, Stanford University, Stanford, CA, USA., Heilshorn SC; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute & Bio-X, Stanford University, Stanford, CA, USA. heilshorn@stanford.edu.; Department of Materials Science and Engineering, Stanford University, Stanford, CA, USA. heilshorn@stanford.edu.

Publikováno v: Nature communications [Nat Commun] 2023 Jul 19; Vol. 14 (1), pp. 4346. Date of Electronic Publication: 2023 Jul 19.