Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Paôline Laurent"'
Autor:
Pauline Henrot, Paôline Laurent, Emeline Levionnois, Damien Leleu, Catherine Pain, Marie-Elise Truchetet, Muriel Cario
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Systemic Sclerosis (SSc) is a complex auto-immune connective tissue disease combining inflammatory, vasculopathic and fibrotic manifestations. Skin effectively recapitulates the main pathogenic processes and therefore is a good organ to decipher the
Externí odkaz:
https://doaj.org/article/f07df389c3e8428fbfdf10cbf685b6fe
Autor:
Thomas Pradeu, Paôline Laurent, Valérie Jolivel, Pauline Manicki, Lynn Chiu, Cécile Contin-Bordes, Marie-Elise Truchetet
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Though the immune system is generally defined as a system of defense, it is increasingly recognized that the immune system also plays a crucial role in tissue repair and its potential dysregulations. In this review, we explore how distinct immune cel
Externí odkaz:
https://doaj.org/article/96270cdf1c6c459ea7eb8e6b3100cd1c
Autor:
Paôline Laurent, Chao Yang, André F. Rendeiro, Benjamin E. Nilsson-Payant, Lucia Carrau, Vasuretha Chandar, Yaron Bram, Benjamin R. tenOever, Olivier Elemento, Lionel B. Ivashkiv, Robert E. Schwartz, Franck J. Barrat
Publikováno v:
Science Immunology. 7
Lung-infiltrating macrophages create a marked inflammatory milieu in a subset of patients with COVID-19 by producing a cytokine storm, which correlates with increased lethality. However, these macrophages are largely not infected by SARS-CoV-2, so th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea3befd4188d1a74a3913b689759bf0
https://doi.org/10.1126/sciimmunol.add4906
https://doi.org/10.1126/sciimmunol.add4906
Autor:
Edouard Forcade, Pierre Duffau, Estibaliz Lazaro, Emeline Levionnois, Carlo Chizzolini, Benoit Allard, Patrick Blanco, Julien Izotte, Joël Constans, Pauline Henrot, Pauline Manicki, Damien Leleu, Paôline Laurent, Thomas Pradeu, Valérie Jolivel, Alexis Groppi, Christophe Richez, Thierry Schaeverbeke, Julien Seneschal, Mohamed Jeljeli, Marie-Elise Truchetet, Frédéric Batteux, Cécile Contin-Bordes
Publikováno v:
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2021, pp.annrheumdis-2020-219748. ⟨10.1136/annrheumdis-2020-219748⟩
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2021, pp.annrheumdis-2020-219748. ⟨10.1136/annrheumdis-2020-219748⟩
ObjectiveInnate lymphoid cells-2 (ILC2) were shown to be involved in the development of lung or hepatic fibrosis. We sought to explore the functional and phenotypic heterogeneity of ILC2 in skin fibrosis within systemic sclerosis (SSc).MethodsBlood s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f351de10dc768e6672ce110189328a8
https://hal.archives-ouvertes.fr/hal-03386391
https://hal.archives-ouvertes.fr/hal-03386391
Autor:
Fédération Hospitalo-Universitaire Acronim, Joël Constans, Béatrice Demoures, Julien Seneschal, Cécile Contin-Bordes, Pierre Duffau, Marie-Elise Truchetet, C. Jacquemin, Jean-Luc Pellegrin, Jorge Eduardo Guimaraes, Valérie Jolivel, Christophe Richez, Anne Bertrand, Paôline Laurent, Marie-Sylvie Doutre, Estibaliz Lazaro, Isabelle Douchet, Thierry Schaeverbeke, Patrick Blanco, Liliane Khoryati
Publikováno v:
Arthritis & Rheumatology. 68:2784-2794
OBJECTIVE To investigate the relationship between vascular damage and fibrosis in systemic sclerosis (SSc) by testing the hypothesis that platelets contribute to skin fibrosis via the activation of human dermal microvascular endothelial cells (HDMECs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5f8a0896005abb9b93af3a802ae62b9
https://doi.org/10.1002/art.39817
https://doi.org/10.1002/art.39817
Autor:
Marie-Elise, Truchetet, Béatrice, Demoures, Jorge, Eduardo Guimaraes, Anne, Bertrand, Paôline, Laurent, Valérie, Jolivel, Isabelle, Douchet, Clément, Jacquemin, Liliane, Khoryati, Pierre, Duffau, Estibaliz, Lazaro, Christophe, Richez, Julien, Seneschal, Marie-Sylvie, Doutre, Jean-Luc, Pellegrin, Joël, Constans, Thierry, Schaeverbeke, Patrick, Blanco, Cécile, Contin-Bordes
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 68(11)
To investigate the relationship between vascular damage and fibrosis in systemic sclerosis (SSc) by testing the hypothesis that platelets contribute to skin fibrosis via the activation of human dermal microvascular endothelial cells (HDMECs) and subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a713bd78f6187d8b78b7f591e32dbe81
https://pubmed.ncbi.nlm.nih.gov/27428811
https://pubmed.ncbi.nlm.nih.gov/27428811
Autor:
Patrick Blanco, Christophe Richez, B. Demoures, Thierry Schaeverbeke, Marie-Elise Truchetet, Pierre Duffau, Joël Constans, Anne Bertrand, Isabelle Douchet, Jean-Luc Pellegrin, Julien Seneschal, Cécile Contin-Bordes, Estibaliz Lazaro, Paôline Laurent, J. Guimaraes
Publikováno v:
Annals of the Rheumatic Diseases. 75:737.2-737
Background Systemic sclerosis (SSc) is a complex systemic autoimmune disease characterized by microvascular dysfunction, immune activation and fibrosis affecting the skin and internal organs (1). Improved characterization of the fibrotic mechanisms i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e8e8a6636d28a71267f45bf9892d335
https://doi.org/10.1136/annrheumdis-2016-eular.2732
https://doi.org/10.1136/annrheumdis-2016-eular.2732
Autor:
Isabelle Douchet, Patrick Blanco, Pierre Duffau, Christophe Richez, Paôline Laurent, Marie-Elise Truchetet, Pauline Manicki, Julien Seneschal, Estibaliz Lazaro, Thomas Pradeu, Cécile Contin-Bordes, Joël Constans
Publikováno v:
Annals of the Rheumatic Diseases. 75:72.1-72
Background Interleukin (IL)13 is considered as a key downstream mediator in the development of Systemic sclerosis (SSc) fibrosis 1 . The recently described type 2 innate lymphoid cells (ILC) produce higher amounts of IL13 than Th2 cells under certain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aef7ee446ae1e220bb213ef5ef0f45e
https://doi.org/10.1136/annrheumdis-2016-eular.3604
https://doi.org/10.1136/annrheumdis-2016-eular.3604
Autor:
Damien Leleu, Emeline Levionnois, Paoline Laurent, Estibaliz Lazaro, Christophe Richez, Pierre Duffau, Patrick Blanco, Vanja Sisirak, Cecile Contin-Bordes, Marie-Elise Truchetet
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
BackgroundMicroparticles (MPs) are vesicular structures that derive from multiple cellular sources. MPs play important roles in intercellular communication, regulation of cell signaling or initiation of enzymatic processes. While MPs were characteriz
Externí odkaz:
https://doaj.org/article/9ecc8c14bc514f05ae4a8574c63ef4bd
Autor:
Paoline Laurent, Vanja Sisirak, Estibaliz Lazaro, Christophe Richez, Pierre Duffau, Patrick Blanco, Marie-Elise Truchetet, Cécile Contin-Bordes
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Systemic sclerosis (SSc) is a heterogeneous autoimmune disease characterized by three interconnected hallmarks (i) vasculopathy, (ii) aberrant immune activation, and (iii) fibroblast dysfunction leading to extracellular matrix deposition and fibrosis
Externí odkaz:
https://doaj.org/article/b9dc683f0420428597cecf4385bfb078