ADP-ribosylation factor (ARF)-like 3, a new member of the ARF family of GTP-binding proteins cloned from human and rat tissues

Autor: Mm, Cavenagh, Breiner M, Annette Schurmann, Ag, Rosenwald, Terui T, Zhang C, Pa, Randazzo, Adams M, Hg, Joost, Ra, Kahn

Publikováno v: Europe PubMed Central

The human and rat homologues of a new member of the ADP-ribosylation factor (ARF) family of 21-kDa GTP-binding proteins, termed Arl3, were identified as an expressed sequence tag (human) and as a product of polymerase chain reaction amplification usi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f5b23cbdfc188085d7047d73db062795
https://pubmed.ncbi.nlm.nih.gov/8034651

Tongue orthotopic xenografts to study fusion-negative rhabdomyosarcoma invasion and metastasis in live animals.

Autor: Hammoudeh SM; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Ng Y; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA; CCR-Intravital Microscopy Core, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Wei BR; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Madsen TD; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA; Copenhagen Center for Glycomics, University of Copenhagen, Department for Cellular and Molecular Medicine, Copenhagen, Denmark., Yadav MP; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Simpson RM; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Weigert R; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA; CCR-Intravital Microscopy Core, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA. Electronic address: weigertr@mail.nih.gov., Randazzo PA; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA. Electronic address: randazzp@mail.nih.gov.

Publikováno v: Cell reports methods [Cell Rep Methods] 2024 Jul 15; Vol. 4 (7), pp. 100802. Date of Electronic Publication: 2024 Jul 03.

Myr-Arf1 conformational flexibility at the membrane surface sheds light on the interactions with ArfGAP ASAP1.

Autor: Zhang Y; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702-1201, USA.; Ring Therapeutics, Inc., Cambridge, MA, USA., Soubias O; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702-1201, USA., Pant S; Theoretical and Computational Biophysics Group, NIH Center for Macromolecular Modeling and Visualization, Beckman Institute for Advanced Science and Technology, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.; Loxo Oncology at Lilly, Louisville, CO, USA., Heinrich F; Department of Physics, Carnegie Mellon University, Pittsburgh, PA, USA.; NIST Center for Neutron Research, Gaithersburg, MD, USA., Vogel A; Institute of Medical Physics and Biophysics, University of Leipzig, 04107, Leipzig, Germany., Li J; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702-1201, USA., Li Y; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702-1201, USA.; Vonsun Pharmatech Co., Ltd., Suzhou, China., Clifton LA; ISIS Neutron and Muon Source, Rutherford Appleton Laboratory, Didcot, Oxfordshire, OX11 0QX, UK., Daum S; Institute for Chemistry, Department of Biophysical Chemistry, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Str. 3A, 06120, Halle, Germany., Bacia K; Institute for Chemistry, Department of Biophysical Chemistry, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Str. 3A, 06120, Halle, Germany., Huster D; Institute of Medical Physics and Biophysics, University of Leipzig, 04107, Leipzig, Germany., Randazzo PA; Laboratory of Cellular and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Lösche M; Department of Physics, Carnegie Mellon University, Pittsburgh, PA, USA.; NIST Center for Neutron Research, Gaithersburg, MD, USA.; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA., Tajkhorshid E; Theoretical and Computational Biophysics Group, NIH Center for Macromolecular Modeling and Visualization, Beckman Institute for Advanced Science and Technology, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA., Byrd RA; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702-1201, USA. byrdra@nih.gov.

Publikováno v: Nature communications [Nat Commun] 2023 Nov 21; Vol. 14 (1), pp. 7570. Date of Electronic Publication: 2023 Nov 21.

The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins.

Autor: Rosenberg EM Jr; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Jian X; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Soubias O; Center for Structural Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA., Yoon HY; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Yadav MP; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Hammoudeh S; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Pallikkuth S; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Akpan I; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Chen PW; Department of Biology, Williams College, Williamstown, Massachusetts, USA., Maity TK; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Jenkins LM; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Yohe ME; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA; Laboratory of Cell and Developmental Signaling, Center for Cancer Research, Frederick, Maryland, USA., Byrd RA; Center for Structural Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA., Randazzo PA; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA. Electronic address: randazzp@mail.nih.gov.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2023 Mar; Vol. 299 (3), pp. 102992. Date of Electronic Publication: 2023 Feb 08.

ERK phosphorylation is dependent on cell adhesion in a subset of pediatric sarcoma cell lines.

Autor: Yoon HY; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States of America., Maron BY; Department of Biology, Williams College, Williamstown, MA, United States of America., Girald-Berlingeri S; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States of America., Gasilina A; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States of America., Gollin JC; Department of Biology, Williams College, Williamstown, MA, United States of America., Jian X; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States of America., Akpan I; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States of America., Yohe ME; Laboratory of Cell and Developmental Signaling, Center for Cancer Research, National Cancer Institute, Frederick, MD, United States of America., Randazzo PA; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States of America. Electronic address: randazzp@mail.nih.gov., Chen PW; Department of Biology, Williams College, Williamstown, MA, United States of America.

Publikováno v: Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2022 Aug; Vol. 1869 (8), pp. 119264. Date of Electronic Publication: 2022 Apr 03.