Expression of cytokeratin 20 and CD44 protein in upper urinary tract transitional cell carcinoma: cytologic-histologic correlation

Autor: Ej, Weaver, Pa, Mccue, Dh, Bagley, Albert Kovatich, Bibbo M

Publikováno v: Europe PubMed Central

To explore the potential utility of immunostaining for CK20 and CD44 protein isoforms in evaluating cases of upper urinary tract transitional cell carcinoma (UTTCC).Of 105 consecutive patients diagnosed cytologically with UTTCC, 33 subsequently under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::719e4acc5505612d201661298eeed242
https://pubmed.ncbi.nlm.nih.gov/11693559

Large granular lymphocyte proliferation: an analysis of T-cell receptor gene arrangement and expression and the effect of in vitro culture with inducing agents

Autor: WC Chan, C Dahl, T Waldmann, S Link, A Mawle, J Nicholson, FH Bach, K Bongiovanni, PA McCue, EF Winton

Publikováno v: Blood. 71:52-58

The status of the T cell receptor beta and gamma genes in natural killer (NK) cells was investigated in two patients with a marked expansion of CD2+, CD3- NK cells. Both genes were found to be in the germline state. The T alpha and complete T beta ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482d061f525503bc824b9b99958320b3
https://doi.org/10.1182/blood.v71.1.52.52

The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy responses.

Autor: Li Z; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, PA, 18902, USA., Jiao X; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, PA, 18902, USA., Robertson AG; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, VSZ 4S6, Canada.; Dxige Research, Courtenay, BC, V9N 1C2, Canada., Di Sante G; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, PA, 18902, USA., Ashton AW; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, PA, 18902, USA.; Lankenau Institute for Medical Research, 100 East Lancaster Avenue, Wynnewood, PA, 19096, USA.; Division of Perinatal Research, Kolling Institute, Northern Sydney Local Health District, St Leonards, NSW, 2065, Australia.; Sydney Medical School Northern, University of Sydney, Sydney, NSW, 2006, Australia., DiRocco A; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, PA, 18902, USA., Wang M; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, PA, 18902, USA., Zhao J; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, PA, 18902, USA., Addya S; Department of Cancer Biology, Thomas Jefferson University, Bluemle Life Sciences Building, 233 South 10th Street, Philadelphia, PA, 19107, USA., Wang C; Department of Cancer Biology, Thomas Jefferson University, Bluemle Life Sciences Building, 233 South 10th Street, Philadelphia, PA, 19107, USA., McCue PA; Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Bluemle Life Sciences Building, 233 South 10th Street, Philadelphia, PA, 19107, USA., South AP; Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Bluemle Life Sciences Building, 233 South 10th Street, Philadelphia, PA, 19107, USA., Cordon-Cardo C; Department of Pathology, Mt. Sinai, Hospital, 1468 Madison Ave., Floor 15, New York, NY, 10029, USA., Liu R; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, PA, 18902, USA., Patel K; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, PA, 18902, USA., Hamid R; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, PA, 18902, USA., Parmar J; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, PA, 18902, USA., DuHadaway JB; Lankenau Institute for Medical Research, 100 East Lancaster Avenue, Wynnewood, PA, 19096, USA., Jones SJM; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, VSZ 4S6, Canada., Casimiro MC; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, PA, 18902, USA.; Abraham Baldwin Agricultural College, Department of Science and Mathematics, Box 15, 2802 Moore Highway, Tifton, GA, 31794, USA., Schultz N; Human Oncology and Pathogenesis Program, Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kossenkov A; Center for Systems and Computational Biology, The Wistar Institute, 3601 Spruce St., Philadelphia, PA, 19104, USA., Phoon LY; Department of Radiation Oncology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.; Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA, USA., Chen H; Department of Radiation Oncology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.; Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA, USA., Lan L; Department of Radiation Oncology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.; Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA, USA., Sun Y; Department of Pathology, Medical College of Wisconsin, Milwaukee, WI, USA., Iczkowski KA; Department of Pathology, Medical College of Wisconsin, Milwaukee, WI, USA., Rui H; Department of Pathology, Medical College of Wisconsin, Milwaukee, WI, USA., Pestell RG; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, PA, 18902, USA. Richard.Pestell@bblumberg.org.; The Wistar Cancer Center, Philadelphia, PA, 19104, USA. Richard.Pestell@bblumberg.org.

Publikováno v: Oncogene [Oncogene] 2023 Jun; Vol. 42 (22), pp. 1857-1873. Date of Electronic Publication: 2023 Apr 24.

A Novel Role for DNA-PK in Metabolism by Regulating Glycolysis in Castration-Resistant Prostate Cancer.

Autor: Dylgjeri E; Department of Cancer Biology at Thomas Jefferson University, Philadelphia, Pennsylvania., Kothari V; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Shafi AA; Department of Cancer Biology at Thomas Jefferson University, Philadelphia, Pennsylvania., Semenova G; Department of Cancer Biology at Thomas Jefferson University, Philadelphia, Pennsylvania., Gallagher PT; Department of Cancer Biology at Thomas Jefferson University, Philadelphia, Pennsylvania., Guan YF; School of Medical Sciences and Prince of Wales Clinical School, UNSW Sydney, Sydney, Australia., Pang A; School of Medical Sciences and Prince of Wales Clinical School, UNSW Sydney, Sydney, Australia., Goodwin JF; Department of Cancer Biology at Thomas Jefferson University, Philadelphia, Pennsylvania., Irani S; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.; Adelaide Medical School and Freemasons Foundation Centre for Male Health and Wellbeing, University of Adelaide, Adelaide, South Australia., McCann JJ; Department of Cancer Biology at Thomas Jefferson University, Philadelphia, Pennsylvania., Mandigo AC; Department of Cancer Biology at Thomas Jefferson University, Philadelphia, Pennsylvania., Chand S; Department of Cancer Biology at Thomas Jefferson University, Philadelphia, Pennsylvania., McNair CM; Department of Cancer Biology at Thomas Jefferson University, Philadelphia, Pennsylvania.; Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania., Vasilevskaya I; Department of Cancer Biology at Thomas Jefferson University, Philadelphia, Pennsylvania.; Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania., Schiewer MJ; Department of Cancer Biology at Thomas Jefferson University, Philadelphia, Pennsylvania.; Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania.; Department of Urology, Medical Oncology and Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania., Lallas CD; Department of Urology, Medical Oncology and Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania., McCue PA; Department of Urology, Medical Oncology and Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania., Gomella LG; Department of Urology, Medical Oncology and Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania., Seifert EL; Department of Pathology, Anatomy and Cell Biology and MitoCare Center, Thomas Jefferson University, Philadelphia, Pennsylvania., Carroll JS; Cancer Research UK Cambridge Research Institute, England, United Kingdom., Butler LM; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.; Adelaide Medical School and Freemasons Foundation Centre for Male Health and Wellbeing, University of Adelaide, Adelaide, South Australia., Holst J; School of Medical Sciences and Prince of Wales Clinical School, UNSW Sydney, Sydney, Australia., Kelly WK; Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania.; Department of Urology, Medical Oncology and Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania., Knudsen KE; Department of Cancer Biology at Thomas Jefferson University, Philadelphia, Pennsylvania.; Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania.; Department of Urology, Medical Oncology and Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2022 Apr 01; Vol. 28 (7), pp. 1446-1459.

The membrane-associated form of cyclin D1 enhances cellular invasion.

Autor: Chen K; Department of Cancer Biology, Thomas Jefferson University, Philadelphia, PA, 19107, USA., Jiao X; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center, Wynnewood, PA, 19096, USA., Ashton A; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center, Wynnewood, PA, 19096, USA., Di Rocco A; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center, Wynnewood, PA, 19096, USA., Pestell TG; Department of Cancer Biology, Thomas Jefferson University, Philadelphia, PA, 19107, USA., Sun Y; Department of Pathology, Medical College of Wisconsin, Milwaukee, WI, 53226, USA., Zhao J; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center, Wynnewood, PA, 19096, USA., Casimiro MC; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center, Wynnewood, PA, 19096, USA.; Dept of Science and Math, Abraham Baldwin Agricultural college, Tifton, GA, 31794, Georgia., Li Z; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center, Wynnewood, PA, 19096, USA., Lisanti MP; Biomedical Research Centre (BRC), Translational Medicine, School of Environment and Life Sciences, University of Salford, Manchester, United Kingdom., McCue PA; Department of Pathology, Anatomy and Cell Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, 19107, USA., Shen D; Departments of Biomedical Engineering, Washington University, St. Louis, MO, 63110, USA., Achilefu S; Departments of Biomedical Engineering, Washington University, St. Louis, MO, 63110, USA.; Departments of Radiology, Washington University, St. Louis, MO, 63110, USA.; Departments of Biochemistry & Molecular Biophysics, Washington University, St. Louis, MO, 63110, USA., Rui H; Department of Pathology, Medical College of Wisconsin, Milwaukee, WI, 53226, USA., Pestell RG; Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center, Wynnewood, PA, 19096, USA. Richard.pestell@bblumberg.org.; The Wistar Cancer Center, Wistar Institute, Philadelphia, PA, 19104, USA. Richard.pestell@bblumberg.org.

Publikováno v: Oncogenesis [Oncogenesis] 2020 Sep 18; Vol. 9 (9), pp. 83. Date of Electronic Publication: 2020 Sep 18.