Zobrazeno 1 - 8
of 8
pro vyhledávání: '"PUR4"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 837-850 (2021)
Neoplasia
Neoplasia (New York, N.Y.)
Neoplasia
Neoplasia (New York, N.Y.)
Highlights • Deletion of fibronectin in cancer cells prolongs survival • Pharmacologic inhibition of fibronectin deposition slows down cancer progression in two models • Decreasing fibronectin in the matrix diminishes proliferation in tumors an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e268ac146863ea724609643109711f0d
https://doi.org/10.1016/j.neo.2021.06.012
https://doi.org/10.1016/j.neo.2021.06.012
Autor:
Ninoshka R. J. Fernandes, Nicholas S. Reilly, Dillon C. Schrock, Denise C. Hocking, Patrick W. Oakes, Deborah J. Fowell
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
The extracellular matrix (ECM) is extensively remodeled during inflammation providing essential guidance cues for immune cell migration and signals for cell activation and survival. There is increasing interest in the therapeutic targeting of ECM to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e467fd02364941dc7ca37a8adad7e770
https://www.frontiersin.org/article/10.3389/fimmu.2020.01501/full
https://www.frontiersin.org/article/10.3389/fimmu.2020.01501/full
Publikováno v:
Journal of Biomedical Science
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-15 (2019)
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-15 (2019)
Background The blood–spinal cord barrier (BSCB) is composed of a monolayer of endothelium linked with tight junctions and extracellular matrix (ECM)-rich basement membranes and is surrounded by astrocyte foot processes. Endothelial permeability is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03ecb9cabd1e5265c325e0b072b0f06
http://europepmc.org/articles/PMC6521375
http://europepmc.org/articles/PMC6521375
Akademický článek
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Publikováno v:
Pharmaceutical research. 35(7)
To develop PEGylated variants of pUR4/FUD (FUD), a fibronectin assembly inhibitor, using 10 kDa, 20 kDa, and 40 kDa PEGs to evaluate their binding affinity and inhibitory potency. The FUD peptide was recombinantly expressed, purified, and PEGylated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1d8b873a517da54e14ff051790583a
https://pubmed.ncbi.nlm.nih.gov/29691664
https://pubmed.ncbi.nlm.nih.gov/29691664
Autor:
Donna M. Peters, Pawel Zbyszynski, Inger Toraason, Glen S. Kwon, Bianca R. Tomasini-Johansson
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205360 (2018)
PLoS ONE
PLoS ONE
Fibronectin is a blood and extracellular matrix glycoprotein that plays important roles in wound healing and fibrosis since it controls the deposition of collagen and other extracellular matrix molecules and is a substrate for infiltrating lymphocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bf2cb5d432df2612cb56efd66dd74f
http://europepmc.org/articles/PMC6200241?pdf=render
http://europepmc.org/articles/PMC6200241?pdf=render
Publikováno v:
Circulation Research. 119
Heart failure (HF) is a devastating disease with poor prognosis. Hallmarks of HF include pathological fibrosis, remodeling and reduced function. In response to cardiac injury, cardiac fibroblasts (CF) undergo pathologic transition to a myofibroblast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c67aab70c1da22a459c5f084c81fe3f
https://doi.org/10.1161/res.119.suppl_1.264
https://doi.org/10.1161/res.119.suppl_1.264
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 29:1074-1079
Objective—Fibronectin is an important regulator of cell migration, differentiation, growth, and survival. Our data show that fibronectin also plays an important role in regulating extracellular matrix (ECM) remodeling. Fibronectin circulates in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3f08dc5998767f54b25406f264fdf4
https://doi.org/10.1161/atvbaha.108.181081
https://doi.org/10.1161/atvbaha.108.181081