Zobrazeno 1 - 2
of 2
pro vyhledávání: '"PTS, peroxisome targeting signal"'
Autor:
Luis F. Godinho, Celien Lismont, Ruth E. Carmichael, Marc Fransen, Peter Freisinger, Christian Hacker, Markus Islinger, Yunhong Wang, Michael Schrader, Sacha Ferdinandusse, Josiah B. Passmore, David M. Richards, Tina A. Schrader
Publikováno v:
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1867(7):118709. Elsevier
Biochimica et Biophysica Acta. Molecular Cell Research
Biochimica et Biophysica Acta. Molecular Cell Research
Peroxisomes are highly dynamic subcellular compartments with important functions in lipid and ROS metabolism. Impaired peroxisomal function can lead to severe metabolic disorders with developmental defects and neurological abnormalities. Recently, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71618f64ddde7c5bfa06a81ad78908a
Publikováno v:
Biochemical Journal
NBP (nitrogen-containing bisphosphonate) drugs protect against excessive osteoclast-mediated bone resorption. After binding to bone mineral, they are taken up selectively by the osteoclasts and inhibit the essential enzyme FDPS (farnesyl diphosphate