Zobrazeno 1 - 10
of 28
pro vyhledávání: '"PSM, peptide spectrum match"'
Autor:
Natalia Ninkina, Owen M. Peters, Natalie Connor-Robson, Kirill D. Chaprov, Holger B. Kramer, Dominic J. Withers, Arthur T. Kopylov, Vladimir L. Buchman, Steven Millership, Alex Montoya
Publikováno v:
The Journal of Biological Chemistry
Synucleins, a family of three proteins highly expressed in neurons, are predominantly known for the direct involvement of α-synuclein in the etiology and pathogenesis of Parkinson's and certain other neurodegenerative diseases, but their precise phy
Autor:
Karl J. Wahlin, Jun Wan, Ravi Chakra Turaga, Cynthia A. Berlinicke, Jiang Qian, Joseph L. Mertz, Melissa M. Liu, Ming-Wen Hu, Donald J. Zack, Srinivasa R. Sripathi, Julien Maruotti
Publikováno v:
Molecular & Cellular Proteomics : MCP
Stress and injury to the retinal pigment epithelium (RPE) often lead to dedifferentiation and epithelial-to-mesenchymal transition (EMT). These processes have been implicated in several retinal diseases, including proliferative vitreoretinopathy, dia
Autor:
Sebastien Leblanc, Marie A. Brunet
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 2836-2850 (2020)
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 2836-2850 (2020)
Graphical abstract
The Zika virus is a flavivirus that can cause fulminant outbreaks and lead to Guillain-Barré syndrome, microcephaly and fetal demise. Like other flaviviruses, the Zika virus is transmitted by mosquitoes and provokes neurologi
The Zika virus is a flavivirus that can cause fulminant outbreaks and lead to Guillain-Barré syndrome, microcephaly and fetal demise. Like other flaviviruses, the Zika virus is transmitted by mosquitoes and provokes neurologi
Publikováno v:
Molecular & Cellular Proteomics : MCP
Human leukocyte antigen (HLA) molecules are cell-surface glycoproteins that present peptide antigens on the cell surface for surveillance by T lymphocytes, which contemporaneously seek signs of disease. Mass spectrometric analysis allows us to identi
Autor:
Hasmik Keshishian, Phuong M. Le, Karl R. Clauser, Steven A. Carr, Suzanna Rachimi, Patrick A. Ott, Annie Apffel, Vipheaviny Chea, Susan Klaeger, Giacomo Oliveira, Catherine J. Wu, Jennifer G. Abelin, Anna Tarren, Derin B. Keskin, Siranush Sarkizova, Nir Hacohen, David A. Braun
Publikováno v:
Molecular & Cellular Proteomics : MCP
MS is the most effective method to directly identify peptides presented on human leukocyte antigen (HLA) molecules. However, current standard approaches often use 500 million or more cells as input to achieve high coverage of the immunopeptidome, and
Autor:
Brian Stevenson, Michal Bassani-Sternberg, George Coukos, Florian Huber, Chloe Chong, Markus Müller, HuiSong Pak, Justine Michaux
Publikováno v:
Molecular & cellular proteomics, vol. 20, pp. 100080
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics : MCP
Mass spectrometry (MS) is the state-of-the-art methodology for capturing the breadth and depth of the immunopeptidome across human leukocyte antigen (HLA) allotypes and cell types. The majority of studies in the immunopeptidomics field are discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3887a4cb5b29beb1c402fbcb2034206b
https://serval.unil.ch/notice/serval:BIB_DCFCF966CE50
https://serval.unil.ch/notice/serval:BIB_DCFCF966CE50
Autor:
Arun Tailor, Robert Parker, Karsten Schnatbaum, Annalisa Nicastri, Holger Wenschuh, Ulf Reimer, Xu Peng, Nicola Ternette, Johannes Zerweck
Publikováno v:
Molecular & Cellular Proteomics : MCP
Standardization of immunopeptidomics experiments across laboratories is a pressing issue within the field, and currently a variety of different methods for sample preparation and data analysis tools are applied. Here, we compared different software p
Autor:
Doron Kletter, Marshall Bern, Yong J. Kil, Gary M. Wilson, Eric Carlson, Wilfred H. Tang, Abhishek Roushan, K. Ilker Sen
Publikováno v:
Molecular & Cellular Proteomics : MCP
Glycopeptides in peptide or digested protein samples pose a number of analytical and bioinformatics challenges beyond those posed by unmodified peptides or peptides with smaller posttranslational modifications. Exact structural elucidation of glycans
Autor:
Marioara Chirițoiu, Simona Ghenea, Gabriela N. Chirițoiu, Andrei-Jose Petrescu, Stefana M. Petrescu, Cristian V.A. Munteanu
Publikováno v:
Molecular & Cellular Proteomics : MCP
Various pathologies result from disruptions to or stress of endoplasmic reticulum (ER) homeostasis, such as Parkinson's disease and most neurodegenerative illnesses, diabetes, pulmonary fibrosis, viral infections, and cancers. A critical process in m
Autor:
Geiszler, Daniel J., Kong, Andy T., Avtonomov, Dmitry M., Yu, Fengchao, Leprevost, Felipe V., Nesvizhskii, Alexey I.
Publikováno v:
Molecular & Cellular Proteomics : MCP
Open searching has proven to be an effective strategy for identifying both known and unknown modifications in shotgun proteomics experiments. Rather than being limited to a small set of user-specified modifications, open searches identify peptides wi