Zobrazeno 1 - 6
of 6
pro vyhledávání: '"PSEN, presenilin"'
Autor:
Naomi Mihira, Misaki Sekiguchi, Kenichi Nagata, Takashi Saito, Toshio Ohshima, Kaori Sato, Hiroki Sasaguri, Takaomi C. Saido, Naoto Watamura, Ryo Fujioka
Publikováno v:
The Journal of Biological Chemistry
We previously developed single App knock-in mouse models of Alzheimer's disease (AD) harboring the Swedish and Beyreuther/Iberian mutations with or without the Arctic mutation (AppNL-G-F and AppNL-F mice, respectively). These models showed Aβ pathol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c901230fb3cfb1cf28cfd7fab0de79ae
https://doi.org/10.1016/j.jbc.2021.101004
https://doi.org/10.1016/j.jbc.2021.101004
Autor:
Robert K. Yu, Michael P. McDonald, Susumu Ando, Yoshio Hirabayashi, Toshio Ariga, Yutaka Itokazu
Publikováno v:
ASN Neuro, Vol 5 (2013)
ASN NEURO
ASN NEURO
In order to examine the potential involvement of gangliosides in AD (Alzheimer's disease), we compared the ganglioside compositions of the brains of a double-transgenic (Tg) mouse model [APP (amyloid precursor protein)/PSEN1 (presenilin)] of AD and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465602687c688dc6a5a4ce1fe6a9d205
https://doaj.org/article/55246adcfe0146fcb4d5b02123e630ba
https://doaj.org/article/55246adcfe0146fcb4d5b02123e630ba
Autor:
Makoto Yanagisawa, Chandramohan G. Wakade, Jerry J. Buccafusco, Susumu Ando, Robert K. Yu, Toshio Ariga, Michael P. McDonald
Publikováno v:
ASN Neuro, Vol 2 (2010)
ASN NEURO
ASN NEURO
The accumulation of Aβ (amyloid β-protein) is one of the major pathological hallmarks in AD (Alzheimer's disease). Gangliosides, sialic acid-containing glycosphingolipids enriched in the nervous system and frequently used as biomarkers associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6415cf5c0ef6726f2e288158d971b13
https://doaj.org/article/a922508338b04cef9698dd10ea2e0360
https://doaj.org/article/a922508338b04cef9698dd10ea2e0360
Autor:
Jürgen Götz, Naeman N. Götz
Publikováno v:
ASN NEURO
ASN Neuro, Vol 1 (2009)
ASN Neuro, Vol 1 (2009)
In dementia research, animal models have become indispensable tools. They not only model aspects of the human condition, but also simulate processes that occur in humans and hence provide insight into how disease is initiated and propagated. The pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c66b5657ec65249461d665642e7de232
http://europepmc.org/articles/PMC2785514
http://europepmc.org/articles/PMC2785514
Akademický článek
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Autor:
Ariga T; Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912, U.S.A., Yanagisawa M, Wakade C, Ando S, Buccafusco JJ, McDonald MP, Yu RK
Publikováno v:
ASN neuro [ASN Neuro] 2010 Oct 04; Vol. 2 (4), pp. e00044. Date of Electronic Publication: 2010 Oct 04.