Zobrazeno 1 - 10
of 206
pro vyhledávání: '"PSAT1"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Clear cell renal cell carcinoma (ccRCC) is associated with a high prevalence of cancer-related deaths. The survival rates of patients are significantly lower in late-stage ccRCC than in early-stage ccRCC, due to the spread and met
Externí odkaz:
https://doaj.org/article/b395daf3e7d44e6d9bd996a720563f89
Autor:
Minchenko Oleksandr H., Sliusar Myroslava Y., Khita Olena O., Minchenko Dmytro O., Viletska Yuliia M., Halkin Oleh V., Levadna Liudmyla O., Cherednychenko Anastasiia A., Khikhlo Yevgen P.
Publikováno v:
Endocrine Regulations, Vol 58, Iss 1, Pp 91-100 (2024)
Objective. Glucose and glutamine supply as well as serine synthesis and endoplasmic reticulum (ER) stress are important factors of glioblastoma growth. Previous studies showed that the knockdown of ERN1 (ER to nucleus signaling 1) suppressed glioblas
Externí odkaz:
https://doaj.org/article/fe2223a129ea40ada897520c36364990
Autor:
Jiaci Li, Xinping Wei, Yuchen Sun, Xiaofang Chen, Ying Zhang, Xiaoyu Cui, Jianbo Shu, Dong Li, Chunquan Cai
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Background Phosphoserine aminotransferase deficiency (PSATD) is an autosomal recessive disorder associated with hypertonia, psychomotor retardation, and acquired microcephaly. Patients with PSATD have low concentrations of serine in plasma a
Externí odkaz:
https://doaj.org/article/b9208681691a42a4884ae4cc78dd8297
Autor:
Xingda Zhang, Siyu Wang, Wei Li, Jianyu Wang, Yajie Gong, Quanrun Chen, Shihan Cao, Da Pang, Song Gao
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 990 (2024)
Background: Accumulating evidence indicates that PSAT1 not only reprogrammed metabolic function but also exhibits “moonlighting” functions in promoting tumor malignancy. However, the underlying molecular mechanisms of PSAT1 promoting ER-negative
Externí odkaz:
https://doaj.org/article/47941299e274494baf0873d29dd0fc2e
Publikováno v:
Thoracic Cancer, Vol 14, Iss 19, Pp 1812-1823 (2023)
Abstract Background Both exosomes and circular RNAs (circRNAs) are involved in tumor growth. Hsa_circ_0001492 (circERBB2IP) has been reported to be overexpressed in plasma exosomes from patients with lung adenocarcinoma, but the biological role of ex
Externí odkaz:
https://doaj.org/article/1777feadecc9483e94c75acd20c39c6a
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Periodontal ligament stem cells (PDLSCs) are important seed cells for tissue engineering to realize the regeneration of alveolar bone. Understanding the gene regulatory mechanisms of osteogenic lineage differentiation in PDLSCs wi
Externí odkaz:
https://doaj.org/article/bd31252974c846dfb44eed14adb7a90e
Autor:
Sliusar Myroslava Y., Minchenko Dmytro O., Khita Olena O., Tsymbal Dariia O., Viletska Yuliia M., Luzina Olha Y., Danilovskyi Serhij V., Ratushna Oksana O., Minchenko Oleksandr H.
Publikováno v:
Endocrine Regulations, Vol 57, Iss 1, Pp 252-261 (2023)
Objective. Serine synthesis as well as endoplasmic reticulum stress and hypoxia are important factors of malignant tumor growth including glioblastoma. Previous studies have shown that the knockdown of ERN1 (endoplasmic reticulum to nucleus signaling
Externí odkaz:
https://doaj.org/article/4aefa70ee11343659d21bbc7b8f50335
Akademický článek
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Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Metabolic reprogramming is an important hallmark of malignant tumors. Serine is a non-essential amino acid involved in cell proliferation. Serine metabolism, especially the de novo serine synthesis pathway, forms a metabolic network with glycolysis,
Externí odkaz:
https://doaj.org/article/f62fb4da132d429ca7eb4909b267d518
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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