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Structural Changes in the Cardiovascular System of Untreated Essential Hypertensives

Autor: A M Sinclair, J Mackay, A.D. Hughes, PS Sever, Andrew N. Nicolaides, J Mayet, M Shahi, SA Thom, G Geroulakos

Publikováno v: Blood Pressure. 4:42-47

Arterial hypertension is associated with structural changes in the cardiovascular system. This study has examined the effect of hypertension on the carotid artery wall and examined the relation between changes in the structure of carotid artery wall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5babe186377bde075d24aeb099269ebf
https://doi.org/10.3109/08037059509077566

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Racial differences in cardiac structure and function in essential hypertension

Autor: Neil R Poulter, J Mayet, Rodney A. Foale, S. A. McG Thom, M Shahi, PS Sever

Publikováno v: BMJ. 308:1011-1014

Objective: To assess racial differences in cardiac structure and function in patients presenting with previously untreated hypertension. Design - Untreated black patients with hypertension were compared with untreated white patients matched for age a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cee9bdd12cc939d90a15ca36d828de2a
https://doi.org/10.1136/bmj.308.6935.1011

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Free-radical scavengers, thiol-containing reagents and endothelium-dependent relaxation in isolated rat and human resistance arteries

Autor: PS Sever, A.D. Hughes, W. Sunman

Publikováno v: Clinical Science. 84:287-295

1. Small arteries were isolated from either rat mesentery or human subcutaneous fat, and mounted in a myograph for the measurement of isometric force. 2. Superoxide dismutase, either in the presence or absence of catalase, relaxed noradrenaline-induc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b510afce31b123614867656e141fcafd
https://doi.org/10.1042/cs0840287

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Neurally evoked responses of human isolated resistance arteries are mediated by both αm1- and α2-adrenoceptors

Autor: PS Sever, Hans Jørgen Nielsen, N.A. Parkinson, A.D. Hughes, S.McG. Thorn, Michael J. Mulvany

Publikováno v: British Journal of Pharmacology. 106:568-573

1. Human subcutaneous resistance arteries (internal diameter 113-626 microns) were mounted in an isometric myograph. Electrical field stimulation was applied either continuously in the form of a frequency-response curve or intermittently at 16 Hz. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837027a53af1450830ea2f62ae9ff4e7
https://doi.org/10.1111/j.1476-5381.1992.tb14376.x

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