Zobrazeno 1 - 10
of 32
pro vyhledávání: '"PRX, peroxiredoxin"'
Publikováno v:
Translational Oncology, Vol 17, Iss, Pp 101341-(2022)
Translational Oncology
Translational Oncology
Highlights • Thioredoxin reductase (TrxR), a seleno enzyme, regulates cellular redox. • Several human cancers are known to overexpress TrxR. • Inhibitors of TrxR have enhanced radiation induced cytotoxicity in multiple cancers. • TrxR could b
Publikováno v:
The Journal of Biological Chemistry
Genetically encoded fluorescent H2O2 probes continue to advance the field of redox biology. Here, we compare the previously established peroxiredoxin-based H2O2 probe roGFP2-Tsa2ΔCR with the newly described OxyR-based H2O2 probe HyPer7, using yeast
Autor:
Kaori Okinaka, Goshi Shiota, Hiroyuki Oka, Tsuyoshi Yokobata, Shizuma Okazaki, Ikuya Noda, Minoru Morimoto, Noriko Itaba, Yohei Kono
Publikováno v:
Regenerative Therapy, Vol 9, Iss, Pp 45-57 (2018)
Regenerative Therapy
Regenerative Therapy
Introduction We previously reported that transplantation of hepatic cell sheets from human bone marrow-derived mesenchymal stem cells (BM-MSCs) with hexachlorophene, a Wnt/β-catenin signaling inhibitor, ameliorated acute liver injury. In a further p
The Circadian Clock Gene Circuit Controls Protein and Phosphoprotein Rhythms in Arabidopsis thaliana
Autor:
Tom Hamborg Nielsen, Karen J. Halliday, Helle K. Mogensen, Gerben VanOoijen, Matthew Hindle, Johanna Krahmer, Andrew J. Millar, Thierry LeBihan, Laura K Perby
Publikováno v:
Molecular & Cellular Proteomics : MCP
Krahmer, J, Hindle, M, Perby, L K, Mogensen, H K, Nielsen, T H, Halliday, K J, van Ooijen, G, Le Bihan, T & Millar, A J 2022, ' The Circadian Clock Gene Circuit Controls Protein and Phosphoprotein Rhythms in Arabidopsis thaliana ', Molecular and Cellular Proteomics, vol. 21, no. 1, 100172 . https://doi.org/10.1016/j.mcpro.2021.100172
Krahmer, J, Hindle, M, Perby, L K, Mogensen, H K, Nielsen, T H, Halliday, K J, VanOoijen, G, LeBihan, T & Millar, A J 2022, ' The circadian clock gene circuit controls protein and phosphoprotein rhythms in Arabidopsis thaliana ', Molecular and Cellular Proteomics, vol. 21, no. 1, 100172 . https://doi.org/10.1016/j.mcpro.2021.100172
Krahmer, J, Hindle, M, Perby, L K, Mogensen, H K, Nielsen, T H, Halliday, K J, van Ooijen, G, Le Bihan, T & Millar, A J 2022, ' The Circadian Clock Gene Circuit Controls Protein and Phosphoprotein Rhythms in Arabidopsis thaliana ', Molecular and Cellular Proteomics, vol. 21, no. 1, 100172 . https://doi.org/10.1016/j.mcpro.2021.100172
Krahmer, J, Hindle, M, Perby, L K, Mogensen, H K, Nielsen, T H, Halliday, K J, VanOoijen, G, LeBihan, T & Millar, A J 2022, ' The circadian clock gene circuit controls protein and phosphoprotein rhythms in Arabidopsis thaliana ', Molecular and Cellular Proteomics, vol. 21, no. 1, 100172 . https://doi.org/10.1016/j.mcpro.2021.100172
Twenty-four-hour, circadian rhythms control many eukaryotic mRNA levels, whereas the levels of their more stable proteins are not expected to reflect the RNA rhythms, emphasizing the need to test the circadian regulation of protein abundance and modi
Autor:
Zorana Carter, Paraskevi Kritsiligkou, Chris J. Kershaw, Chris M. Grant, Alan J. Weids, Karol Nowicki-Osuch, Declan R. Creamer
Publikováno v:
The Journal of Biological Chemistry
Protein aggregation is the abnormal association of misfolded proteins into larger, often insoluble structures that can be toxic during aging and in protein aggregation-associated diseases. Previous research has established a role for the cytosolic Ts
Autor:
Konstantinos Filis, Fragiska Sigala, Sven Zukunft, Beate Fisslthaler, Janina Wittig, Ralf P. Brandes, Andreas Papapetropoulos, Matthias S. Leisegang, Sofia Iris Bibli, Andrea Kapasakalidi, Jiong Hu, Ingrid Fleming, Diamantis I. Tsilimigras, Georgios Zografos
Publikováno v:
Redox Biology, Vol 28, Iss, Pp-(2020)
Redox Biology
Redox Biology
Cystathionine γ lyase (CSE) is the major source of hydrogen sulfide-derived species (H2Sn) in endothelial cells and plays an important role in protecting against atherosclerosis. Here we investigated the molecular mechanisms underlying the regulatio
Publikováno v:
Journal of Molecular Biology
Starting with the beginning of the last century, a multitude of scientific studies has documented that the lunar cycle times behaviors and physiology in many organisms. It is plausible that even the first life forms adapted to the different rhythms c
Publikováno v:
Redox Biology, Vol 19, Iss, Pp 166-178 (2018)
Redox Biology
Redox Biology
Atherosclerosis remains the number one cause of death and disability worldwide. Atherosclerosis is treated by revascularization procedures to restore blood flow to distal tissue, but these procedures often fail due to restenosis secondary to neointim
Autor:
Yu Jeong Jeong, Dae-Woon Eom, Sungbo Shim, Sun-Uk Kim, Sung Joo Kim, Seung-Mo Hong, Yena Jung, Young-Ho Park, Peter C.W. Lee, In-Sung Song, Sung-Wuk Jang
Publikováno v:
Redox Biology
Redox Biology, Vol 48, Iss, Pp 102190-(2021)
Redox Biology, Vol 48, Iss, Pp 102190-(2021)
Cancer stem cells (CSCs) initiate tumor formation and are known to be resistant to chemotherapy. A metabolic alteration in CSCs plays a critical role in stemness and survival. However, the association between mitochondrial energy metabolism and the r
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Redox Biology, Vol 11, Iss, Pp 543-553 (2017)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Redox Biology
instname
Redox Biology, Vol 11, Iss, Pp 543-553 (2017)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Redox Biology
Neurodegenerative diseases are linked to the accumulation of specific protein aggregates, suggesting an intimate connection between injured brain and loss of proteostasis. Proteostasis refers to all the processes by which cells control the abundance