Zobrazeno 1 - 10
of 74
pro vyhledávání: '"PRR, Pattern Recognition Receptor"'
Autor:
Jun Kobayashi
Publikováno v:
Nitric Oxide
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide and has seriously threatened public health by causing significant morbidity and mortality. Patients with coronavirus disease (COVID-19) with preexisting endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97dbc32e2c6c06eab04e000be1c5a1bd
https://doi.org/10.1016/j.niox.2021.08.001
https://doi.org/10.1016/j.niox.2021.08.001
Publikováno v:
Pulmonology, Vol 27, Iss 5, Pp 423-437 (2021)
Pulmonology
Pulmonology
SARS-CoV-2 is a new beta coronavirus, similar to SARS-CoV-1, that emerged at the end of 2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID-19), which was declared a pandemic by the World Health Organization on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9b7f4bc7b02b1302a387d92564f7ba
https://doi.org/10.1016/j.pulmoe.2021.03.008
https://doi.org/10.1016/j.pulmoe.2021.03.008
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 249-272 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 249-272 (2021)
Background & Aims TNFSF15 genetic variants leading to increased TNF superfamily member 15 (TNFSF15) expression confer risk for inflammatory bowel disease (IBD), and TNFSF15 is being explored as a therapeutic target in IBD patients. Although the focus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb21b1a8b74b5bc07131da592a5389bd
https://doi.org/10.1016/j.jcmgh.2020.08.003
https://doi.org/10.1016/j.jcmgh.2020.08.003
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 315-329 (2021)
Computational and Structural Biotechnology Journal, 19
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 315-329 (2021)
Computational and Structural Biotechnology Journal, 19
Biotherapeutics, and antimicrobial proteins in particular, are of increasing interest for human medicine. An important challenge in the development of such therapeutics is their potential immunogenicity, which can induce production of anti-drug-antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc6eb34d6710e1da9ae4b3df006a799
https://doi.org/10.1016/j.csbj.2020.12.024
https://doi.org/10.1016/j.csbj.2020.12.024
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 12, Pp 1499-1506 (2020)
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal : SPJ
Osteoarthritis (OA) is a disease characterized by degeneration of the joint complex due to cartilage destruction. Fraxetin, a widely used and studied coumarin compound extracted from a traditional Chinese herb (Qin Pi), has shown anti-inflammatory an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e983a5ffbb58806e56a84e82964e7f0
http://www.sciencedirect.com/science/article/pii/S1319016420302218
http://www.sciencedirect.com/science/article/pii/S1319016420302218
Autor:
Miyong Yun, Young-Su Yi
Publikováno v:
Journal of Ginseng Research, Vol 44, Iss 3, Pp 373-385 (2020)
Journal of Ginseng Research
Journal of Ginseng Research
Inflammation is an immune response that protects against pathogens and cellular stress. The hallmark of inflammatory responses is inflammasome activation in response to various stimuli. This subsequently activates downstream effectors, that is, infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f329426609bf78cf66d558eb1ea7ae14
http://www.sciencedirect.com/science/article/pii/S1226845319302830
http://www.sciencedirect.com/science/article/pii/S1226845319302830
Publikováno v:
Seminars in Immunology
Graphical abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged pathogen that has caused coronavirus disease 2019 (COVID-19), the worst pandemic of our times leading to tremendous loss of human life and unpr
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged pathogen that has caused coronavirus disease 2019 (COVID-19), the worst pandemic of our times leading to tremendous loss of human life and unpr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b54b4adb408a46b7343cb6a38b77d2
http://europepmc.org/articles/PMC8576141
http://europepmc.org/articles/PMC8576141
Publikováno v:
Invertebrate Survival Journal, Vol 3, Iss 2, Pp 103-110 (2006)
The innate immune system discriminates between infectious non-self and self using germ-line-encoded pattern recognition receptors (PRRs) that are highly conserved from insects to mammals. Peptidoglycan recognition protein (PGRP) is one of the hallmar
Externí odkaz:
https://doaj.org/article/2b8ab12063bf4b00baaca97a5cb142bf
Autor:
Denise Veltman, Piet Claus, Ellen Caluwé, Maarten Vanhaverbeke, Uwe Himmelreich, Stefan Janssens, Peter Pokreisz, Peter Sinnaeve, Willy Gsell, Ming Wu, Hilde Gillijns
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • The role of the CLEC4E during myocardial healing after ischemia-reperfusion injury is unknown. • CLEC4E deletion is associated with reduced cardiac injury, inflammation, and left ventricular structural and functi
Highlights • The role of the CLEC4E during myocardial healing after ischemia-reperfusion injury is unknown. • CLEC4E deletion is associated with reduced cardiac injury, inflammation, and left ventricular structural and functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a46fac4ecaf99cf50513516da72175
https://lirias.kuleuven.be/handle/123456789/680542
https://lirias.kuleuven.be/handle/123456789/680542
Autor:
Rui Sun, Clara Abraham
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 4, Pp 673-697 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Interleukin (IL)23 is a major contributor to inflammatory bowel disease (IBD) pathogenesis and is being pursued as a therapeutic target, both through targeting IL23 alone or in combination with IL12. Unexpected trial outcomes highli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad178b92adfc5ec39a7be2f0f160e40
https://doi.org/10.1016/j.jcmgh.2020.05.007
https://doi.org/10.1016/j.jcmgh.2020.05.007