Zobrazeno 1 - 10
of 36 230
pro vyhledávání: '"PROTEIN DEGRADATION"'
Autor:
Schuh MP; Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA. meredith.posner@cchmc.org., Bennett MR; Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA., Lane A; Division of Bone Marrow Transplantation, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA., Jodele S; Division of Bone Marrow Transplantation, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA., Laskin BL; Division of Nephrology, The Children's Hospital of Philadelphia and the Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Devarajan P; Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA.
Publikováno v:
Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2019 May; Vol. 34 (5), pp. 865-871. Date of Electronic Publication: 2018 Dec 19.
Publikováno v:
IBRO Neuroscience Reports, Vol 17, Iss , Pp 423-430 (2024)
Introduction: Neurofibrillary tangles (NFTs) are composed of hyperphosphorylated forms of microtubule-associated protein tau (Tau), which is responsible for neurodegeneration in Alzheimer’s disease (AD). The hippocampal region has been a major focu
Externí odkaz:
https://doaj.org/article/b1ad43a822624b44b8a40b174895f499
Publikováno v:
hLife, Vol 2, Iss 11, Pp 576-591 (2024)
Various precise gene editing techniques at the DNA/RNA level, driven by clustered regularly interspaced short palindrome repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) technology, have gained significant prominence. Yet, research on targeted pro
Externí odkaz:
https://doaj.org/article/8d24ef6e0b5d4e57a9c289ab18cfe041
Autor:
Hülya Hanoğlu Oral
Publikováno v:
Turkish Journal of Agriculture: Food Science and Technology, Vol 12, Iss 10, Pp 1762-1771 (2024)
For protein evaluation of feedstuffs for ruminants, the Streptomyces griseus protease test offers a purely enzymatic approach to estimate ruminal protein degradation. This study was conducted to determine the enzymatic crude protein (CP) degradabilit
Externí odkaz:
https://doaj.org/article/fa68e901fce143a0a539e029700efe47
Autor:
Bo Chen, Qi Zhang, Sen Wang, Xing-ai Guan, Wan-xin Luo, Dong-fang Li, Yue He, Shu-jing Huang, Ya-ting Zhou, Jun-long Zhao, Lan He
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Background Babesia duncani is a pathogen within the phylum Apicomplexa that causes human babesiosis. It poses a significant threat to public health, as it can be transmitted not only through tick bites but also via blood transfusion. Consequ
Externí odkaz:
https://doaj.org/article/efecd796b72641bb9d320d31a351979f
Autor:
Baldassarre M; IRCSS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; Centre for Applied Biomedical Research-CRBA, Alma Mater Studiorum University of Bologna, St. Orsola Hospi, tAlbologna, Italy., Naldi M; Centre for Applied Biomedical Research-CRBA, Alma Mater Studiorum University of Bologna, St. Orsola Hospi, tAlbologna, Italy.; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, Bologna, Italy., Zaccherini G; IRCSS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy., Bartoletti M; IRCSS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy., Antognoli A; IRCSS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy., Laggetta M; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy., Gagliardi M; Centre for Applied Biomedical Research-CRBA, Alma Mater Studiorum University of Bologna, St. Orsola Hospi, tAlbologna, Italy.; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy., Tufoni M; IRCSS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Domenicali M; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.; Department of Internal Medicine, S. Maria delle Croci Hospital, AUSL Romagna, Ravenna, Italy., Waterstradt K; MedInnovation GmbH, Berlin, Germany., Paterini P; IRCSS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; Centre for Applied Biomedical Research-CRBA, Alma Mater Studiorum University of Bologna, St. Orsola Hospi, tAlbologna, Italy., Baldan A; IRCSS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Leoni S; IRCSS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Bartolini M; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, Bologna, Italy., Viale P; IRCSS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy., Trevisani F; IRCSS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy., Bernardi M; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy., Caraceni P; IRCSS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.
Publikováno v:
Hepatology (Baltimore, Md.) [Hepatology] 2021 Oct; Vol. 74 (4), pp. 2058-2073. Date of Electronic Publication: 2021 May 26.
Autor:
Ziqi Huang, Kun Zhang, Yurui Jiang, Mengmeng Wang, Mei Li, Yuda Guo, Ruolin Gao, Ning Li, Chenyang Wang, Jia Chen, Jiefu Wang, Ning Liu, Xiang Liu, Shuangwei Liu, Mingming Wei, Cheng Yang, Guang Yang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4001-4013 (2024)
Cancer stem cells (CSCs) play a pivotal role in tumor initiation, proliferation, metastasis, drug resistance, and recurrence. Consequently, targeting CSCs has emerged as a promising avenue for cancer therapy. Recently, 3-phosphoglycerate dehydrogenas
Externí odkaz:
https://doaj.org/article/f12cd5184227441eb476af3f499d3c9a
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-24 (2024)
Abstract Targeted therapies, such as small molecule kinase inhibitors, have made significant progress in the treatment of hematologic malignancies by directly modulating protein activity. However, issues such as drug toxicity, drug resistance due to
Externí odkaz:
https://doaj.org/article/44aa040c0e97457dbd58f150108b00d7