Prediction of cognition in Parkinson's disease with a clinical–genetic score: a longitudinal analysis of nine cohorts

Autor: Liu, Ganqiang, Locascio, Joseph J, Winder-Rhodes, Sophie, Vidailhet, Marie, Bonnet, Anne-Marie, Bonnet, Cecilia, Corvol, Jean-Christophe, Elbaz, Alexis, Grabli, David, Hartmann, Andreas, Klebe, Stephan, Lacomblez, Lucette, Mangone, Graziella, Tanner, Caroline M, Bourdain, Frédéric, Brandel, Jean-Philippe, Derkinderen, Pascal, Durif, Franck, Mesnage, Valérie, Pico, Fernando, Rascol, Olivier, Brefel-Courbon, Christine, Ory-Magne, Fabienne, Lang, Anthony E, Forlani, Sylvie, Lesage, Suzanne, Tahiri, Khadija, Albin, Roger, Alcalay, Roy, Ascherio, Alberto, Bowman, Dubois, Chen-Plotkin, Alice, Dawson, Ted, Eberly, Shirley, Dewey, Richard, German, Dwight, Saunders-Pullman, Rachel, Scherzer, Clemens, Vaillancourt, David, Petyuk, Vladislav, West, Andy, Zhang, Jing, Brice, Alexis, Ravina, Bernard, Shoulson, Ira, Cormier-Dequaire, Florence, Heutink, Peter, van Hilten, Jacobus J, Barker, Roger A, Williams-Gray, Caroline H, Marinus, Johan, Scherzer, Clemens R, HBS, CamPaIGN, PICNICS, PROPARK, Boot, Brendon, PSG, DIGPD, PDBP, Hyman, Bradley T, Ivinson, Adrian J, Trisini-Lipsanopoulos, Ana, Franco, Daly, Burke, Kyle, Sudarsky, Lewis R, Liao, Zhixiang, Hayes, Michael T, Umeh, Chizoba C, Sperling, Reisa, Growdon, John H, Schwarzschild, Michael A, Hung, Albert Y, Flaherty, Alice W, Blacker, Deborah, Wills, Anne-Marie, Sohur, U Shivraj, Page, Kara, Mejia, Nicte I, Viswanathan, Anand, Gomperts, Stephen N, Khurana, Vikram, Albers, Mark W, Alora-Palli, Maria, McGinnis, Scott, Sharma, Nutan, Dickerson, Bradford, Frosch, Matthew, Gomez-Isla, Teresa, Greenberg, Steven, Gusella, James, Hedden, Trey, Hedley-Whyte, E Tessa, Koenig, Aaron, Marquis-Sayagues, Marta, Marshall, Gad, Okereke, Olivia, Stemmer-Rachaminov, Anat, Kloppenburg, Jessica, Schlossmacher, Michael G, Selkoe, Dennis J, Yi, Thomas, Li, Haining, Stalberg, Gabriel, Jansen, Iris E, Barker, Roger, Foltynie, Tom, Williams-Gray, Caroline, Robbins, Trevor, Brayne, Carol, Mason, Sarah, Breen, David P, Cummins, Gemma, Evans, Jonathan, Mallet, Alain

Publikováno v: The Lancet Neurology, 16(8), 620-629. Lancet Publishing Group
The lancet / Neurology 16(8), 620-629 (2017). doi:10.1016/S1474-4422(17)30122-9
Liu, G, Locascio, J J, Corvol, J C, Boot, B, Liao, Z, Page, K, Franco, D, Burke, K, Jansen, I E, Trisini-Lipsanopoulos, A, Winder-Rhodes, S, Tanner, C M, Lang, A E, Eberly, S, Elbaz, A, Brice, A, Mangone, G, Ravina, B, Shoulson, I, Cormier-Dequaire, F, Heutink, P, van Hilten, J J, Barker, R A, Williams-Gray, C H, Marinus, J & Scherzer, C R 2017, ' Prediction of cognition in Parkinson's disease with a clinical–genetic score : a longitudinal analysis of nine cohorts ', The Lancet Neurology, vol. 16, no. 8, pp. 620-629 . https://doi.org/10.1016/S1474-4422(17)30122-9
The Lancet Neurology, 16(8), 620-629

Summary Background Cognitive decline is a debilitating manifestation of disease progression in Parkinson's disease. We aimed to develop a clinical–genetic score to predict global cognitive impairment in patients with the disease. Methods In this lo

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https://research.vumc.nl/en/publications/6b6b3533-b145-4979-8a44-ac24734cd334