Consequences of gene editing of PRLR on thermotolerance, growth, and male reproduction in cattle.

Autor: Cuellar, Camila J.¹ (AUTHOR), Amaral, Thiago F.¹ (AUTHOR), Rodriguez‐Villamil, Paula² (AUTHOR), Ongaratto, F.² (AUTHOR), Martinez, D. Onan^1,3 (AUTHOR), Labrecque, Rémi⁴ (AUTHOR), Losano, João D. de Agostini¹ (AUTHOR), Estrada‐Cortés, Eliab^1,5 (AUTHOR), Bostrom, Jonathan R.² (AUTHOR), Martins, Kyra² (AUTHOR), Rae, D. Owen³ (AUTHOR), Block, Jeremy⁶ (AUTHOR), Hoorn, Quinn A.¹ (AUTHOR), Daigneault, Bradford W.¹ (AUTHOR), Merriam, Jonathan⁴ (AUTHOR), Lohuis, Michael⁴ (AUTHOR), Dikmen, Serdal^1,7 (AUTHOR), Bittar, João H. J.³ (AUTHOR), Maia, Tatiane S.¹ (AUTHOR), Carlson, Daniel F.⁸ (AUTHOR)

Publikováno v: FASEB Bioadvances. Aug2024, Vol. 6 Issue 8, p223-234. 12p.

Consequences of gene editing of PRLR on thermotolerance, growth, and male reproduction in cattle

Autor: Camila J. Cuellar, Thiago F. Amaral, Paula Rodriguez‐Villamil, F. Ongaratto, D. Onan Martinez, Rémi Labrecque, João D. de Agostini Losano, Eliab Estrada‐Cortés, Jonathan R. Bostrom, Kyra Martins, D. Owen Rae, Jeremy Block, Quinn A. Hoorn, Bradford W. Daigneault, Jonathan Merriam, Michael Lohuis, Serdal Dikmen, João H. J. Bittar, Tatiane S. Maia, Daniel F. Carlson, Sabreena Larson, Tad S. Sonstegard, Peter J. Hansen

Publikováno v: FASEB BioAdvances, Vol 6, Iss 8, Pp 223-234 (2024)

Abstract Global warming is a major challenge to the sustainable and humane production of food because of the increased risk of livestock to heat stress. Here, the example of the prolactin receptor (PRLR) gene is used to demonstrate how gene editing c

Externí odkaz: https://doaj.org/article/9c2fdecfd6fc42c2b2aef21505d1da0e

High Prolactin Concentration Induces Ovarian Granulosa Cell Oxidative Stress, Leading to Apoptosis Mediated by L-PRLR and S-PRLR.

Autor: Yang, Ruochen¹ (AUTHOR) yangruochen1110@126.com, Duan, Chunhui¹ (AUTHOR) duanchh211@126.com, Zhang, Shuo² (AUTHOR) 17835424912@163.com, Guo, Yunxia³ (AUTHOR) gyx310@163.com, Shan, Xinyu¹ (AUTHOR) 13932229451@163.com, Chen, Meijing¹ (AUTHOR) chenmeijing815@126.com, Yue, Sicong¹ (AUTHOR) yueyueyuexiaojuan@163.com, Zhang, Yingjie¹ (AUTHOR) zhangyingjie@hebau.edu.cn, Liu, Yueqin¹ (AUTHOR) zhangyingjie@hebau.edu.cn

Publikováno v: International Journal of Molecular Sciences. Oct2023, Vol. 24 Issue 19, p14407. 19p.

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A novel bispecific antibody targeting CD3 and prolactin receptor (PRLR) against PRLR-expression breast cancer.

Autor: Zhou, Yuexian^1,2 (AUTHOR), Zong, Huifang^1,2 (AUTHOR), Han, Lei^1,2 (AUTHOR), Xie, Yueqing³ (AUTHOR), Jiang, Hua³ (AUTHOR), Gilly, John³ (AUTHOR), Zhang, Baohong^1,2 (AUTHOR), Lu, Huili^1,2 (AUTHOR), Chen, Jie^1,2 (AUTHOR), Sun, Rui^1,2 (AUTHOR), Pan, Zhidi^1,2 (AUTHOR), Zhu, Jianwei^1,2,3,4 (AUTHOR) jianweiz@sjtu.edu.cn

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 5/12/2020, Vol. 39 Issue 1, p1-14. 14p.