Zobrazeno 1 - 10
of 872
pro vyhledávání: '"PRION PROTEIN GENE"'
Autor:
Adeniyi C. Adeola, Semiu F. Bello, Abdussamad M. Abdussamad, Rahamon A. M. Adedokun, Sunday C. Olaogun, Nasiru Abdullahi, Akanbi I. Mark, Anyebe B. Onoja, Oscar J. Sanke, Godwin F. Mangbon, Jebi Ibrahim, Philip M. Dawuda, Adebowale E. Salako, Samia Kdidi, Mohamed Habib Yahyaoui
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background Prion diseases, also known as transmissible spongiform encephalopathies (TSEs) remain one of the deleterious disorders, which have affected several animal species. Polymorphism of the prion protein (PRNP) gene majorly determines t
Externí odkaz:
https://doaj.org/article/5f55834d046b42c3ba17e3f75a4fcd0f
Autor:
Adeniyi C. Adeola, Semiu F. Bello, Abdussamad M. Abdussamad, Akanbi I. Mark, Oscar J. Sanke, Anyebe B. Onoja, Lotanna M. Nneji, Nasiru Abdullahi, Sunday C. Olaogun, Lawal D. Rogo, Godwin F. Mangbon, Shamsudeen L. Pedro, Manasseh P. Hiinan, Muhammad M. Mukhtar, Jebi Ibrahim, Hayatu Saidu, Philip M. Dawuda, Rukayya K. Bala, Hadiza L. Abdullahi, Adebowale E. Salako, Samia Kdidi, Mohamed Habib Yahyaoui, Ting-Ting Yin
Publikováno v:
Prion, Vol 17, Iss 1, Pp 44-54 (2023)
ABSTRACTPolymorphism of the prion protein gene (PRNP) gene determines an animal’s susceptibility to scrapie. Three polymorphisms at codons 136, 154, and 171 have been linked to classical scrapie susceptibility, although many variants of PRNP have b
Externí odkaz:
https://doaj.org/article/2274b99e97f04244993cb90ddb6409f6
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
BackgroundPrion diseases have been extensively reported in various mammalian species and are caused by a pathogenic prion protein (PrPSc), which is a misfolded version of cellular prion protein (PrPC). Notably, no cases of prion disease have been rep
Externí odkaz:
https://doaj.org/article/c33fd846fd294f4f885acbbf8caead60
Publikováno v:
Prion, Vol 16, Iss 1, Pp 7-13 (2022)
An 84-year-old woman who had been diagnosed as having dementia with Lewy body (DLB) upon initial examination exhibited cognitive impairments and person delusional misidentification (DMS): she transiently claimed that her spouse was a stranger. She wa
Externí odkaz:
https://doaj.org/article/9032d51623b1407498a49c79e7c801ab
Publikováno v:
Prion, Vol 16, Iss 1, Pp 14-18 (2022)
Genetic Creutzfeldt–Jakob disease (gCJD) is a prion disease caused by mutations in the prion protein gene (PRNP). It has an autosomal dominant inheritance, so gCJD with homozygous mutations is extremely rare, and the influence of homozygous mutatio
Externí odkaz:
https://doaj.org/article/187e298172bb4a86b3f506207c1e3b91
Autor:
Alberto F. Fameli, Jessie Edson, Jeremiah E. Banfield, Christopher S. Rosenberry, W. David Walter
Publikováno v:
Prion, Vol 16, Iss 1, Pp 254-264 (2022)
Chronic wasting disease (CWD) is a fatal encephalopathy affecting North American cervids. Certain alleles in a host’s prion protein gene are responsible for reduced susceptibility to CWD. We assessed for the first time variability in the prion prot
Externí odkaz:
https://doaj.org/article/311258454b8c45daa87d16d6a2346775
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Autor:
Zhongyun Chen, Min Chu, Li Liu, Jing Zhang, Yu Kong, Kexin Xie, Yue Cui, Hong Ye, Junjie Li, Lin Wang, Liyong Wu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-11 (2022)
Abstract Background To elucidate the clinical and ancillary features of genetic prion diseases (gPrDs) presenting with frontotemporal dementia (FTD) to aid early identification. Methods Global data of gPrDs presenting with FTD caused by prion protein
Externí odkaz:
https://doaj.org/article/dbbee531409448a898790b55d43e0c01
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Prion diseases are fatal degenerative encephalopathies caused by misfolded prion protein (PrPSc) converted from normal prion protein (PrPC). Previous studies have reported that genetic polymorphisms of the prion protein gene (PRNP) play a critical ro
Externí odkaz:
https://doaj.org/article/fbe842c48a104a859121e3dfc0665b66
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Transmissible spongiform encephalopathies (TSEs) also known as prion diseases, are fatal neurodegenerative diseases. Prion diseases are caused by abnormal prion protein (PrPSc) derived from normal prion protein (PrPC), which is encoded by the prion p
Externí odkaz:
https://doaj.org/article/37d979f9c0ad433dbec8856b931ee15f