Zobrazeno 1 - 10
of 1 826
pro vyhledávání: '"PRIMARY IMMUNODEFICIENCIES"'
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 20, Iss 1, Pp 1-12 (2024)
Abstract Primary immunodeficiency diseases (PIDs), also referred to as inborn errors of immunity, constitute a group of genetic conditions that affect the immune system. The current standard of care for patients with PIDs is lifelong immunoglobulin r
Externí odkaz:
https://doaj.org/article/3f0e845f14cc460288c7d73005448387
Autor:
Christine Phillips, Anne Parkinson, Tergel Namsrai, Anita Chalmers, Carolyn Dews, Dianne Gregory, Elaine Kelly, Christine Lowe, Jane Desborough
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background People with a rare disease commonly experience long delays from the onset of symptoms to diagnosis. Rare diseases are challenging to diagnose because they are clinically heterogeneous, and many present with non-specific symptoms c
Externí odkaz:
https://doaj.org/article/25ad777b5cdf42e09d0f50625663dff4
Autor:
Alejandro Tarango-García, Silvia Rodríguez-Narciso, Netzahualcóyotl Castañeda-Leyva, Hannia M. Prieto-Nevárez, Saul O. Lugo Reyes, Francisco J. Espinosa-Rosales, Sara Elva Espinosa-Padilla, Aidé T. Staines-Boone, Luis F. Torres-Bernal, Aristóteles Álvarez-Cardona
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
PurposeImmunoglobulin replacement therapy remains a cornerstone of treatment in antibody deficiencies and other inborn errors of immunity. While patient preferences between subcutaneous and intravenous immunoglobulin have been studied through questio
Externí odkaz:
https://doaj.org/article/6863d3b3930f4d35a89dfaa3c2bc73bb
Autor:
Katarzyna Napiórkowska-Baran, Jarosław Biliński, Małgorzata Pujanek, Paweł Hałakuc, Antoni Pietryga, Bartłomiej Szymczak, Aleksander Deptuła, Tomasz Rosada, Zbigniew Bartuzi
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
The gut microbiota serves a crucial role in the development of host immunity. Immunocompromised patients are particularly vulnerable to dysbiosis not only by virtue of a defect in the immune system but also due to increased susceptibility to infectio
Externí odkaz:
https://doaj.org/article/fc700d0cc5364d6f84620496447432b6
Autor:
Vera Gallo, Alessandro Aiuti
Publikováno v:
Global Pediatrics, Vol 9, Iss , Pp 100196- (2024)
Nowadays, gene therapy hast the potential to cure an increasingly greater number of monogenic inherited disorders with absent or limited treatment options, and radically change their natural history. Hematopoietic stem cells (HSCs) represent one of t
Externí odkaz:
https://doaj.org/article/273f6e1a82a44028a275bf205d8006d5
Autor:
Siobhan Oisin Burns, Nizar Mahlaoui
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/826d9dbf32534be98997a9a0ebed8ac6
Publikováno v:
Frontiers in Epidemiology, Vol 4 (2024)
Survival analysis (also referred to as time-to-event analysis) is the study of the time elapsed from a starting date to some event of interest. In practice, these analyses can be challenging and, if methodological errors are to be avoided, require th
Externí odkaz:
https://doaj.org/article/fbe26d6115144430b6862ba12198cebb
Publikováno v:
Медицинская иммунология, Vol 26, Iss 1, Pp 203-210 (2024)
The main cause of edema in hereditary angioedema (HAE) is due to elevated bradykinin levels, caused either by C1-INH deficiency/change in functional activity and caused by mutations in the SERPING1 gene or by mutations in the F12, PLG, ANGPT1, KNG1,
Externí odkaz:
https://doaj.org/article/144bc2614ce5426faf54790c0e0504a4
Autor:
Samya Van Coillie, Johan Prévot, Silvia Sánchez-Ramón, David M. Lowe, Michael Borg, Brigitte Autran, Gesmar Segundo, Antonio Pecoraro, Nicolas Garcelon, Cornelis Boersma, Susana L. Silva, Jose Drabwell, Isabella Quinti, Isabelle Meyts, Adli Ali, Siobhan O. Burns, Martin van Hagen, Martine Pergent, Nizar Mahlaoui
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The International Patient Organisation for Primary Immunodeficiencies (IPOPI) held its second Global Multi-Stakeholders’ Summit, an annual stimulating and forward-thinking meeting uniting experts to anticipate pivotal upcoming challenges and opport
Externí odkaz:
https://doaj.org/article/a360c4410d354f929b13dc536d9cc795
Autor:
Ezgi Balkarlı, Selime Özen Bölük, Ömer Akçal, İlke Taşkırdı, İdil Akay Haci, Nesrin Gülez, Ferah Genel
Publikováno v:
Journal of Behçet Uz Children's Hospital, Vol 13, Iss 3, Pp 185-191 (2023)
Objective: As a primary immunodeficiency X-linked agammaglobulinemia (XLA) that develops due to Bruton tyrosine kinase signal transduction protein deficiency which progresses with antibody deficiency was firstly described by an American pediatrician
Externí odkaz:
https://doaj.org/article/d4aa6fb2506b461298462fcc904c67dd