Zobrazeno 1 - 10
of 59 760
pro vyhledávání: '"PRECISION ONCOLOGY"'
Autor:
Alwazzan, Omnia, Gallagher-Syed, Amaya, Millner, Thomas, Patras, Ioannis, Marino, Silvia, Slabaugh, Gregory
Developing a central nervous system (CNS) tumor classifier by integrating DNA methylation data with Whole Slide Images (WSI) offers significant potential for enhancing diagnostic precision in neuropathology. Existing approaches typically integrate en
Externí odkaz:
http://arxiv.org/abs/2411.17418
We present a new unified graph-based representation of medical data, combining genetic information and medical records of patients with medical knowledge via a unique knowledge graph. This approach allows us to infer meaningful information and explan
Externí odkaz:
http://arxiv.org/abs/2410.14739
Autor:
Johannes Weller, Anna‐Laura Potthoff, Thomas Zeyen, Christina Schaub, Cathrina Duffy, Matthias Schneider, Ulrich Herrlinger
Publikováno v:
Molecular Oncology, Vol 18, Iss 12, Pp 2927-2950 (2024)
The concept of precision oncology, the application of targeted drugs based on comprehensive molecular profiling, has revolutionized treatment strategies in oncology. This review summarizes the current status of precision oncology in glioblastoma (GBM
Externí odkaz:
https://doaj.org/article/e9a4c9ccc168445b969bf1b09603be97
Autor:
Gazola, Antonia A.1 (AUTHOR), Lautert-Dutra, William2 (AUTHOR), Archangelo, Leticia Frohlich3 (AUTHOR), Reis, Rodolfo B. dos4 (AUTHOR), Squire, Jeremy A.2,5 (AUTHOR) squirej@fmrp.usp.br
Publikováno v:
Molecular Cytogenetics (17558166). 11/14/2024, Vol. 17 Issue 1, p1-18. 18p.
Autor:
Luvhengo, Thifhelimbilu Emmanuel1 (AUTHOR) maeyane.moeng@wits.ac.za, Moeng, Maeyane Stephens1 (AUTHOR) nosisa.sishuba@yahoo.com, Sishuba, Nosisa Thabile1 (AUTHOR), Makgoka, Malose2 (AUTHOR) malose.makgoka@up.ac.za, Jonas, Lusanda3 (AUTHOR) lusandajonas@yahoo.com, Mamathuntsha, Tshilidzi Godfrey3 (AUTHOR) tshilidzimamathuntsha@gmail.com, Mbambo, Thandanani4 (AUTHOR) mbambot@gmail.com, Kagodora, Shingirai Brenda5 (AUTHOR) brenda.kagodora@wits.ac.za, Dlamini, Zodwa6 (AUTHOR) zodwa.dlamini@up.ac.za
Publikováno v:
Cancers. Oct2024, Vol. 16 Issue 20, p3469. 25p.
Autor:
Rayyan Tariq Khan, Petra Pokorna, Jan Stourac, Simeon Borko, Adam Dobias, Joan Planas-Iglesias, Stanislav Mazurenko, Ihor Arefiev, Gaspar Pinto, Veronika Szotkowska, Jaroslav Sterba, Jiri Damborsky, Ondrej Slaby, David Bednar
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 24, Iss , Pp 734-738 (2024)
Next-generation sequencing technology has created many new opportunities for clinical diagnostics, but it faces the challenge of functional annotation of identified mutations. Various algorithms have been developed to predict the impact of missense v
Externí odkaz:
https://doaj.org/article/3d4ec3367bee4e13870e203cd22157b5
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2049-2056 (2024)
Multi-omics technologies, encompassing genomics, proteomics, and transcriptomics, provide profound insights into cancer biology. A fundamental computational approach for analyzing multi-omics data is differential analysis, which identifies molecular
Externí odkaz:
https://doaj.org/article/647efc60b8b44e57b892665d37e7c503