Zobrazeno 1 - 10
of 49
pro vyhledávání: '"PRC2, polycomb repressive complex 2"'
Autor:
Jyothishmathi Swaminathan, Shinji Maegawa, Shavali Shaik, Ajay Sharma, Javiera Bravo-Alegria, Lei Guo, Lin Xu, Arif Harmanci, Vidya Gopalakrishnan
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The RE1 Silencing Transcription Factor (REST) is a major regulator of neurogenesis and brain development. Medulloblastoma (MB) is a pediatric brain cancer characterized by a blockade of neuronal specification. REST gene expression is aberrantly eleva
Externí odkaz:
https://doaj.org/article/adbcf35e4afc4f71ab1fa836a5a1653c
Autor:
Serena Buontempo, Pasquale Laise, James M. Hughes, Sebastiano Trattaro, Vivek Das, Chantal Rencurel, Giuseppe Testa
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The Polycomb Repressive Complex 2 (PRC2) plays important roles in the epigenetic regulation of cellular development and differentiation through H3K27me3-dependent transcriptional repression. Aberrant PRC2 activity has been associated with cancer and
Externí odkaz:
https://doaj.org/article/364545fc5725480b9422d154b7645c28
Autor:
Elisa Del Savio, Roberta Maestro
Publikováno v:
Cells, Vol 11, Iss 17, p 2626 (2022)
Epithelioid sarcoma (ES) is a very rare and aggressive mesenchymal tumor of unclear origin and uncertain lineage characterized by a prevalent epithelioid morphology. The only recurrent genetic alteration reported in ES as yet is the functional inacti
Externí odkaz:
https://doaj.org/article/f8b4b55d85a742c094b4ba448dcbdc39
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2880-2899 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2880-2899 (2021)
Aberrant activation of NLRP3 inflammasome in colonic macrophages strongly associates with the occurrence and progression of ulcerative colitis. Although targeting NLRP3 inflammasome has been considered to be a potential therapy, the underlying mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b197d7e1bd61447a9d7a45da0a56387
https://doi.org/10.1016/j.apsb.2021.03.011
https://doi.org/10.1016/j.apsb.2021.03.011
Autor:
Xiaohui Pan, Bo Yang, Hongjie Guo, Shuyuan Cheng, Xi Chen, Ling Ding, Qiaojun He, Wenxin Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 5, Pp 723-733 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Immunotherapy strategies targeting the programmed cell death ligand 1 (PD-L1)/programmed cell death 1 (PD-1) pathway in clinical treatments have achieved remarkable success in treating multiple types of cancer. However, owing to the heterogeneity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ca7b0479f6fea7a89a3e1eb06905c5
https://doi.org/10.1016/j.apsb.2019.09.006
https://doi.org/10.1016/j.apsb.2019.09.006
Autor:
Daniel S. Ziemianowicz, Daniel J. Saltzberg, D. Alex Crowder, Christoph U. Schräder, Andrej Sali, Troy J. Pells, Morgan Hepburn, David C. Schriemer
Publikováno v:
Molecular & Cellular Proteomics : MCP
Proteomics methodology has expanded to include protein structural analysis, primarily through cross-linking mass spectrometry (XL-MS) and hydrogen–deuterium exchange mass spectrometry (HX-MS). However, while the structural proteomics community has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59d88f6161e32bbbe5a3291a6c1d235
http://europepmc.org/articles/PMC8452774
http://europepmc.org/articles/PMC8452774
Publikováno v:
Pharmacology & Therapeutics
Individuals differ substantially in their response to pharmacological treatment. Personalized medicine aspires to embrace these inter-individual differences and customize therapy by taking a wealth of patient-specific data into account. Pharmacogenom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c77b497b32c4399ec51c1cb33968c9c
https://doi.org/10.1016/j.pharmthera.2019.01.002
https://doi.org/10.1016/j.pharmthera.2019.01.002
Akademický článek
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Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
George, Joel Johnson, Oittinen, Mikko, Martin-Diaz, Laura, Zapilko, Veronika, Iqbal, Sharif, Rintakangas, Terhi, Arrojo Martins, Fábio Tadeu, Niskanen, Henri, Katajisto, Pekka, Kaikkonen, Minna U., Viiri, Keijo
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Microfold cells (M cells) are immunosurveillance epithelial cells located in the Peyer’s patches (PPs) in the intestine and are responsible for monitoring and transcytosis of antigens, microorganisms, and pathogens. Mature M cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0511565661bab7ecb23552fd9353c399
https://trepo.tuni.fi/handle/10024/133793
https://trepo.tuni.fi/handle/10024/133793
