Zobrazeno 1 - 10
of 94
pro vyhledávání: '"PRAGUE, Melanie"'
Publikováno v:
In Epidemics March 2024 46
We present a parameter estimation method for nonlinear mixed effect models based on ordinary differential equations (NLME-ODEs). The method presented here aims at regularizing the estimation problem in presence of model misspecifications, practical i
Externí odkaz:
http://arxiv.org/abs/2102.11543
Autor:
Colas, Cédric, Hejblum, Boris, Rouillon, Sébastien, Thiébaut, Rodolphe, Oudeyer, Pierre-Yves, Moulin-Frier, Clément, Prague, Mélanie
Publikováno v:
Journal of Artificial Intelligence Research-2021
Epidemiologists model the dynamics of epidemics in order to propose control strategies based on pharmaceutical and non-pharmaceutical interventions (contact limitation, lock down, vaccination, etc). Hand-designing such strategies is not trivial becau
Externí odkaz:
http://arxiv.org/abs/2010.04452
Publikováno v:
The R Journal (2021)
Implementations in R of classical general-purpose algorithms for local optimization generally have two major limitations which cause difficulties in applications to complex problems: too loose convergence criteria and too long calculation time. By re
Externí odkaz:
http://arxiv.org/abs/2009.03840
Autor:
Commenges, Daniel, Prague, Mélanie
We consider the problem of defining the effect of an intervention on a time-varying risk factor or treatment for a disease or a physiological marker; we develop here the latter case. So, the system considered is $(Y,A,C)$, where $Y=(Y_t)$, is the mar
Externí odkaz:
http://arxiv.org/abs/1907.12804
In a randomized study, leveraging covariates related to the outcome (e.g. disease status) may produce less variable estimates of the effect of exposure. For contagion processes operating on a contact network, transmission can only occur through ties
Externí odkaz:
http://arxiv.org/abs/1610.00039
Combination Antiretroviral Therapy (cART) succeeds to control viral replication in most HIV infected patients. This is normally followed by a reconstitution of the CD4$^+$ T cells pool; however, this does not happen for a substantial proportion of pa
Externí odkaz:
http://arxiv.org/abs/1602.05399
Autor:
Prague, Melanie
La plupart des patients infectés par le VIH ont une charge virale qui peut être rendue indétectable par des combinaisons antirétrovirales hautement actives (cART); cependant, il existe des effets secondaires aux traitements. L'utilisation des mod
Externí odkaz:
http://www.theses.fr/2013BOR22056/document
Semi-parametric methods are often used for the estimation of intervention effects on correlated outcomes in cluster-randomized trials (CRTs). When outcomes are missing at random (MAR), Inverse Probability Weighted (IPW) methods incorporating baseline
Externí odkaz:
http://arxiv.org/abs/1507.01822
Autor:
Dutton, Susan J., Madurasinghe, Vichithranie, Morgan, Katy, Stuart, Beth, Fielding, Katherine, Cornelius, Victoria, Turner, Elizabeth L., Hooper, Richard, Giraudeau, Bruno, Seed, Paul T., Nickless, Alecia, Grayling, Michael, Prague, Melanie, Kerry, Sally, Bell, Lauren, Watson, Eila, Gafoor, Rafael, Marlin, Nadine, Yorganci, Emel, Smith, Lesley, Mbekwe, Murielle, Teerenstra, Steven, Chan, Claire, Moerbeek, Mirjam, Jacobsen, Pamela, Bond, Simon, Jones, Ben, Preisser, John, Kanaan, Mona, Hewitt, Catherine, Easter, Christina, Pellatt-Higgins, Tracy, Pankhurst, Laura, Agbla, Schadrac C., Eldridge, Sandra, Lerner, Robin G., Leyrat, Clémence, Pilling, Mark, Forman, Julia R., Bhattacharya, Indrani, Magill, Nicholas, Candlish, Jane, McDowell, Cliona, Martin, James, Kristunas, Caroline, Allen, Elizabeth, Seward, Nadine, Nicholls, Elaine, Franklin, Bryony Dean, Hemming, Karla, Carroll, Kelly, Thompson, Jennifer, Forbes, Andrew, Taljaard, Monica
Publikováno v:
In Journal of Clinical Epidemiology March 2019 107:77-88