Zobrazeno 1 - 10
of 20
pro vyhledávání: '"PRABHAKAR VISWANATHAN"'
Autor:
PETER ROSSING, STEFAN ANKER, GERASIMOS FILIPPATOS, BERTRAM PITT, LUIS M. RUILOPE, VIVIAN FONSECA, GUILLERMO E. UMPIERREZ, LUIZA CARAMORI, MARC LAMBELET, PRABHAKAR VISWANATHAN, ROBERT LAWATSCHECK, AMER JOSEPH, GEORGE BAKRIS
Publikováno v:
Diabetes. 71
Introduction: Finerenone reduced risk of cardiorenal outcomes in patients with CKD and T2D in the FIDELIO-DKD and FIGARO-DKD studies. In FIDELIO-DKD the effects of finerenone on kidney and CV outcomes were consistent irrespective of glucagon-like pep
Autor:
Brooke M. Faught, David Portman, Prabhakar Viswanathan, William B. White, Laura A. Williams, Julie Krop
Publikováno v:
Obstetrics & Gynecology. 135:21S
Publikováno v:
Clinical Pharmacology in Drug Development. 4:175-183
This double-blind, randomized, placebo- and active-controlled, parallel group trial evaluated the potential for multiple-dose fasiglifam to prolong the QT/QTc interval in healthy adults. A total of 280 men and women aged 18-50 years were randomized t
Autor:
Eric Q. Wu, Claudia Lopez, Raluca Ionescu-Ittu, Morgan Bron, Prabhakar Viswanathan, Dominick Latremouille-Viau, Annie Guerin
Publikováno v:
Journal of Medical Economics. 17:646-657
To describe the distribution of costs and to identify the drivers of high costs among adult patients with type 2 diabetes mellitus (T2DM) receiving oral hypoglycemic agents.T2DM patients using oral hypoglycemic agents and having HbA1c test data were
Autor:
Himanshu Naik, Jingtao Wu, Tomoaki Higuchi, Nobuhito Dote, E Leifke, Prabhakar Viswanathan, Majid Vakilynejad
Publikováno v:
The Journal of Clinical Pharmacology. 52:1007-1016
TAK-875 is a selective G-protein-coupled receptor 40 agonist in development for the treatment of type 2 diabetes mellitus. This randomized, double-blind, placebo-controlled study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynam
Autor:
Charlie Cao, E Leifke, Benhuai Xie, Prabhakar Viswanathan, Charles F. Burant, Majid Vakilynejad, John Marcinak
Publikováno v:
The Lancet. 379:1403-1411
Activation of free fatty acid receptor 1 (FFAR1; also known as G-protein-coupled receptor 40) by fatty acids stimulated glucose-dependent β-cell insulin secretion in preclinical models. We aimed to assess whether selective pharmacological activation
Autor:
Paresh Dandona, Prabhakar Viswanathan, Ajay Chaudhuri, Priya Mohanty, Chang Ling Sia, Sanaa Abuaysheh, Rupali Deopurkar, Jay Friedman, Husam Ghanim
Publikováno v:
Diabetes Care
OBJECTIVE We have recently shown that a high-fat high-carbohydrate (HFHC) meal induces an increase in plasma concentrations of endotoxin (lipopolysaccharide [LPS]) and the expression of Toll-like receptor-4 (TLR-4) and suppresser of cytokine signalin
Autor:
Susan Howard, Manish Upadhyay, Paresh Dandona, Sandeep Dhindsa, Ajay Chaudhuri, Prabhakar Viswanathan
Publikováno v:
Endocrine Practice. 14:1000-1005
� Objective: To determine whether prostate-specific antigen (PSA) concentrations in type 2 diabetic men with hypogonadotrophic hypogonadism are lower than those in eugonadal men with type 2 diabetes and whether PSA concentrations are related to pla
Autor:
Shreyas Ravishankar, Prabhakar Viswanathan, Chinmay Patel, Paresh Dandona, Husam Ghanim, Chang Ling Sia, Priya Mohanty
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 92:4476-4479
Background: Because obesity is associated with chronic oxidative and inflammatory stress, and high-fat, high-carbohydrate meals induce significant oxidative and inflammatory stress in normal subjects, we have now hypothesized that the intake of a hig
Publikováno v:
Clinical pharmacology in drug development. 4(3)
This double-blind, randomized, placebo- and active-controlled, parallel group trial evaluated the potential for multiple-dose fasiglifam to prolong the QT/QTc interval in healthy adults. A total of 280 men and women aged 18-50 years were randomized t