Cardiac conduction system regeneration prevents arrhythmias after myocardial infarction.

Autor: Sayers JR; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Martinez-Navarro H; Department of Computer Science, British Heart Foundation Centre of Research Excellence, University of Oxford, Oxford, UK., Sun X; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., de Villiers C; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Sigal S; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Weinberger M; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Rodriguez CC; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Riebel LL; Department of Computer Science, British Heart Foundation Centre of Research Excellence, University of Oxford, Oxford, UK., Berg LA; Department of Computer Science, British Heart Foundation Centre of Research Excellence, University of Oxford, Oxford, UK., Camps J; Department of Computer Science, British Heart Foundation Centre of Research Excellence, University of Oxford, Oxford, UK., Herring N; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Rodriguez B; Department of Computer Science, British Heart Foundation Centre of Research Excellence, University of Oxford, Oxford, UK., Sauka-Spengler T; Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Stowers Institute for Medical Research, Kansas City, MO, USA., Riley PR; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK. paul.riley@idrm.ox.ac.uk.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK. paul.riley@idrm.ox.ac.uk.

Publikováno v: Nature cardiovascular research [Nat Cardiovasc Res] 2025 Jan 03. Date of Electronic Publication: 2025 Jan 03.

Role of the Lymphatics in Cardiac Disease.

Autor: Cooper STE; Institute of Developmental and Regenerative Medicine, Department of Physiology, Anatomy and Genetics, University of Oxford, United Kingdom., Lokman AB; Institute of Developmental and Regenerative Medicine, Department of Physiology, Anatomy and Genetics, University of Oxford, United Kingdom., Riley PR; Institute of Developmental and Regenerative Medicine, Department of Physiology, Anatomy and Genetics, University of Oxford, United Kingdom.

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2024 Jun; Vol. 44 (6), pp. 1181-1190. Date of Electronic Publication: 2024 Apr 18.

Distinct epicardial gene regulatory programs drive development and regeneration of the zebrafish heart.

Autor: Weinberger M; Department of Physiology, Anatomy and Genetics, Institute of Developmental & Regenerative Medicine, University of Oxford, Oxford OX3 7TY, Oxfordshire, UK; Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, Oxfordshire, UK., Simões FC; Department of Physiology, Anatomy and Genetics, Institute of Developmental & Regenerative Medicine, University of Oxford, Oxford OX3 7TY, Oxfordshire, UK., Gungoosingh T; Department of Physiology, Anatomy and Genetics, Institute of Developmental & Regenerative Medicine, University of Oxford, Oxford OX3 7TY, Oxfordshire, UK., Sauka-Spengler T; Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, Oxfordshire, UK; Stowers Institute for Medical Research, Kansas City, MO, USA. Electronic address: TSauka-Spengler@stowers.org., Riley PR; Department of Physiology, Anatomy and Genetics, Institute of Developmental & Regenerative Medicine, University of Oxford, Oxford OX3 7TY, Oxfordshire, UK. Electronic address: paul.riley@idrm.ox.ac.uk.

Publikováno v: Developmental cell [Dev Cell] 2024 Feb 05; Vol. 59 (3), pp. 351-367.e6. Date of Electronic Publication: 2024 Jan 17.

Ac/Ds transposition for CRISPR/dCas9-SID4x epigenome modulation in zebrafish.

Autor: Chong-Morrison V; University of Oxford, Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford OX3 9DS, UK., Mayes S; University of Oxford, Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford OX3 9DS, UK., Simões FC; University of Oxford, Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford OX3 9DS, UK.; University of Oxford, Institute of Developmental and Regenerative Medicine, Department of Physiology, Anatomy and Genetics, Oxford OX3 7DQ, UK., Senanayake U; University of Oxford, Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford OX3 9DS, UK., Carroll DS; University of Oxford, Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford OX3 9DS, UK., Riley PR; University of Oxford, Institute of Developmental and Regenerative Medicine, Department of Physiology, Anatomy and Genetics, Oxford OX3 7DQ, UK., Wilson SW; University College London, Department of Cell & Developmental Biology, London WC1E 6BT, UK., Sauka-Spengler T; University of Oxford, Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford OX3 9DS, UK.; Stowers Institute for Medical Research, Kansas City, MO 64110, USA.

Publikováno v: Biology open [Biol Open] 2023 Jun 15; Vol. 12 (6). Date of Electronic Publication: 2023 Jun 27.

Rapid neutrophil mobilization by VCAM-1+ endothelial cell-derived extracellular vesicles.

Autor: Akbar N; Division of Cardiovascular Medicine, Radcliffe Department of Medicine University of Oxford Level 6, West Wing John Radcliffe Hospital Headington Oxford OX3 9DU, UK., Braithwaite AT; Division of Cardiovascular Medicine, Radcliffe Department of Medicine University of Oxford Level 6, West Wing John Radcliffe Hospital Headington Oxford OX3 9DU, UK., Corr EM; NYU Cardiovascular Research Center, Department of Medicine, Division of Cardiology, School of Medicine, New York University School of Medicine, 435 E 30th St. New York, NY 10016, USA., Koelwyn GJ; NYU Cardiovascular Research Center, Department of Medicine, Division of Cardiology, School of Medicine, New York University School of Medicine, 435 E 30th St. New York, NY 10016, USA., van Solingen C; NYU Cardiovascular Research Center, Department of Medicine, Division of Cardiology, School of Medicine, New York University School of Medicine, 435 E 30th St. New York, NY 10016, USA., Cochain C; Comprehensive Heart Failure Center, University Hospital Wurzburg, Anstalt des öffentlichen Rechts Josef-Schneider-Straße 2 97080 Würzburg, Germany., Saliba AE; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz-Center for Infection Research (HZI), Inhoffenstraße 7 38124 Braunschweig, Würzburg, Germany., Corbin A; Kennedy Institute of Rheumatology, University of Oxford, Roosevelt Dr, Headington, Oxford OX3 7FY, UK., Pezzolla D; Division of Cardiovascular Medicine, Radcliffe Department of Medicine University of Oxford Level 6, West Wing John Radcliffe Hospital Headington Oxford OX3 9DU, UK., Møller Jørgensen M; Department of Clinical Immunology, Aalborg University Hospital, Urbansgade 32-36, DK-9000, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Søndre Skovvej 15, Aalborg, Denmark., Bæk R; Department of Clinical Medicine, Aalborg University, Søndre Skovvej 15, Aalborg, Denmark., Edgar L; Division of Cardiovascular Medicine, Radcliffe Department of Medicine University of Oxford Level 6, West Wing John Radcliffe Hospital Headington Oxford OX3 9DU, UK., De Villiers C; Department of Physiology, Anatomy and Genetics, University of Oxford, Sherrington Building Parks Road, OX1 3PT, Oxford, UK., Gunadasa-Rohling M; Department of Physiology, Anatomy and Genetics, University of Oxford, Sherrington Building Parks Road, OX1 3PT, Oxford, UK., Banerjee A; Division of Cardiovascular Medicine, Radcliffe Department of Medicine University of Oxford Level 6, West Wing John Radcliffe Hospital Headington Oxford OX3 9DU, UK., Paget D; Division of Cardiovascular Medicine, Radcliffe Department of Medicine University of Oxford Level 6, West Wing John Radcliffe Hospital Headington Oxford OX3 9DU, UK., Lee C; Division of Cardiovascular Medicine, Radcliffe Department of Medicine University of Oxford Level 6, West Wing John Radcliffe Hospital Headington Oxford OX3 9DU, UK., Hogg E; Division of Cardiovascular Medicine, Radcliffe Department of Medicine University of Oxford Level 6, West Wing John Radcliffe Hospital Headington Oxford OX3 9DU, UK., Costin A; Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK., Dhaliwal R; Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK., Johnson E; Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK., Krausgruber T; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, Vienna, Austria., Riepsaame J; Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK., Melling GE; Department of Biological and Medical Sciences, Oxford Brookes University, Headington Campus Oxford OX3 0BP, UK.; Institute of Clinical Sciences, School of Biomedical Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Shanmuganathan M; Division of Cardiovascular Medicine, Radcliffe Department of Medicine University of Oxford Level 6, West Wing John Radcliffe Hospital Headington Oxford OX3 9DU, UK.; The OxAMI Study is detailed in the Supplementary Acknowledgments.; Acute Vascular Imaging Centre, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK., Bock C; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, Vienna, Austria.; Institute of Artificial Intelligence, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Spitalgasse 23, BT88 1090, Vienna, Austria., Carter DRF; Department of Biological and Medical Sciences, Oxford Brookes University, Headington Campus Oxford OX3 0BP, UK., Channon KM; Division of Cardiovascular Medicine, Radcliffe Department of Medicine University of Oxford Level 6, West Wing John Radcliffe Hospital Headington Oxford OX3 9DU, UK.; The OxAMI Study is detailed in the Supplementary Acknowledgments.; Acute Vascular Imaging Centre, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK., Riley PR; Department of Physiology, Anatomy and Genetics, University of Oxford, Sherrington Building Parks Road, OX1 3PT, Oxford, UK., Udalova IA; Kennedy Institute of Rheumatology, University of Oxford, Roosevelt Dr, Headington, Oxford OX3 7FY, UK., Moore KJ; NYU Cardiovascular Research Center, Department of Medicine, Division of Cardiology, School of Medicine, New York University School of Medicine, 435 E 30th St. New York, NY 10016, USA., Anthony DC; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK., Choudhury RP; Division of Cardiovascular Medicine, Radcliffe Department of Medicine University of Oxford Level 6, West Wing John Radcliffe Hospital Headington Oxford OX3 9DU, UK.; The OxAMI Study is detailed in the Supplementary Acknowledgments.; Acute Vascular Imaging Centre, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2023 Mar 17; Vol. 119 (1), pp. 236-251.