Zobrazeno 1 - 10
of 289
pro vyhledávání: '"PPMI"'
Autor:
Amin Tajerian
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting over 3% of those over 65. It's caused by reduced dopaminergic neurons and Lewy bodies, leading to motor and non-motor symptoms. The relationship between COMT gene
Externí odkaz:
https://doaj.org/article/8dda56b88f3049cebc6c9c6b779deff2
Publikováno v:
BMC Genomics, Vol 23, Iss S6, Pp 1-12 (2023)
Abstract Background More and more studies show that lncRNA is widely involved in various physiological processes of the organism. However, the functions of the vast majority of them continue to be unknown. In addition, data related to lncRNAs in biol
Externí odkaz:
https://doaj.org/article/5399eebffb9b4b7dabc34cebaa7c19e3
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionParkinson’s disease (PD) is a neurodegenerative and polygenic disorder characterised by the progressive loss of neural dopamine and onset of movement disorders. We previously described eight SINE-VNTR-Alu (SVA) retrotransposon-insertion
Externí odkaz:
https://doaj.org/article/7257bcbcd1bb4b03a073b3c479c1e84b
Publikováno v:
Diagnostics, Vol 14, Iss 9, p 929 (2024)
Background and objective: The symptoms of most neurodegenerative diseases, including Parkinson’s disease (PD), usually do not occur until substantial neuronal loss occurs. This makes the process of early diagnosis very challenging. Hence, this rese
Externí odkaz:
https://doaj.org/article/9821151cc252464c9fc493cf4c52d610
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionThe extensive clinical variations observed in Parkinson's disease (PD) pose challenges in early diagnosis and treatment initiation. However, genetic research in PD has significantly transformed the clinical approach to its treatment. More
Externí odkaz:
https://doaj.org/article/9eb2b86f68964426ab3eb97fc1fef15b
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-19 (2023)
Abstract Background With the development of biotechnology and the accumulation of theories, many studies have found that microRNAs (miRNAs) play an important role in various diseases. Uncovering the potential associations between miRNAs and diseases
Externí odkaz:
https://doaj.org/article/77946c2d154f4f1ab85b84d4b2ab0e46
Akademický článek
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Akademický článek
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Autor:
Alexander S. Mihaescu, Mikaeel Valli, Carme Uribe, Maria Diez-Cirarda, Mario Masellis, Ariel Graff-Guerrero, Antonio P. Strafella
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-13 (2022)
Abstract The accumulation of beta amyloid in the brain has a complex and poorly understood impact on the progression of Parkinson’s disease pathology and much controversy remains regarding its role, specifically in cognitive decline symptoms. Some
Externí odkaz:
https://doaj.org/article/432abdb240b04d1691b12bee5c326c65
Autor:
Charlotte B. Stewart, David Ledingham, Victoria K. Foster, Kirstie N. Anderson, Sahana Sathyanarayana, Debra Galley, Nicola Pavese, Jacopo Pasquini
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/6966f84413414820b8da88135a5021b8