Phytoconstituents from ten natural herbs as potent inhibitors of main protease enzyme of SARS-COV-2: in silico study

Autor: Kavita Bhagat, Preet Mohinder Singh Bedi, Atamjit Singh, Amit Duggal, Puja Gulati, Komalpreet Kaur, Shilpa Dudhal, Harmandeep Kaur Gulati, Jatinder Vir Singh, Jaspreet Kaur, Harbinder Singh, Nitish Kumar

Publikováno v: Phytomedicine Plus
Phytomedicine Plus, Vol 1, Iss 4, Pp 100083-(2021)

Background Lack of treatment of novel Coronavirus disease led to the search of specific antivirals that are capable to inhibit the replication of the virus. The plant kingdom has demonstrated to be an important source of new molecules with antiviral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939ef681815567886f1f3e386c85714b
http://europepmc.org/articles/PMC8180089

Hydroethanolic extract from Endopleura uchi (Huber) Cuatrecasas and its marker bergenin: Toxicological and pharmacokinetic studies in silico and in vivo on zebrafish.

Autor: de Sá Hyacienth BM; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil.; Postgraduate Program in Biodiversity and Biotechnology of the Legal Amazon of the BIONORTE Network, Department of Biological Sciences and Health, Federal University of Amapá, Macapá, AP, Brazil., Tavares Picanço KR; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., Sánchez-Ortiz BL; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil.; Laboratory of Natural Product Pharmacology, Department of Pharmacy, Faculty of Chemistry, National Autonomous University of Mexico, University City, Coyoacán, Zip Code 04510 Mexico City, Mexico., Barros Silva L; Federal University of Amapá, Laboratory of Modeling and Computational Chemistry, Department of Biological Sciences and Health, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., Matias Pereira AC; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., Machado Góes LD; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., Sousa Borges R; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., Cardoso Ataíde R; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., Dos Santos CBR; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil.; Federal University of Amapá, Laboratory of Modeling and Computational Chemistry, Department of Biological Sciences and Health, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., de Oliveira Carvalho H; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., Gonzalez Anduaga GM; Laboratory of Natural Product Pharmacology, Department of Pharmacy, Faculty of Chemistry, National Autonomous University of Mexico, University City, Coyoacán, Zip Code 04510 Mexico City, Mexico., Navarrete A; Laboratory of Natural Product Pharmacology, Department of Pharmacy, Faculty of Chemistry, National Autonomous University of Mexico, University City, Coyoacán, Zip Code 04510 Mexico City, Mexico., Tavares Carvalho JC; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil.; Postgraduate Program in Biodiversity and Biotechnology of the Legal Amazon of the BIONORTE Network, Department of Biological Sciences and Health, Federal University of Amapá, Macapá, AP, Brazil.

Publikováno v: Toxicology reports [Toxicol Rep] 2020 Jan 27; Vol. 7, pp. 217-232. Date of Electronic Publication: 2020 Jan 27 (Print Publication: 2020).