Zobrazeno 1 - 10
of 1 749
pro vyhledávání: '"PPARS"'
Autor:
Sourav Pal, Sayed Mohammed Firdous
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract Cancer is a multifaceted disease characterized by the gradual accumulation of genetic and epigenetic alterations within cells, leading to uncontrolled cell growth and invasive behavior. The intricate interplay between environmental factors,
Externí odkaz:
https://doaj.org/article/accceb8dc1d54cfe8dfbf0af55b29cb3
Autor:
Yeong-Seon Won, Seon-Gyeong Bak, Nisansala Chandimali, Eun Hyun Park, Hyung-Jin Lim, Hyuck Se Kwon, Sang-Ik Park, Seung Jae Lee
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Overweight, often known as obesity, is the abnormal and excessive accumulation of fat that exposes the health of a person at risk by increasing the likelihood that they may experience many chronic conditions. Consequently, obesity
Externí odkaz:
https://doaj.org/article/fc4c3aeb3622439eae2e52d8673deb75
Publikováno v:
BMC Molecular and Cell Biology, Vol 25, Iss 1, Pp 1-7 (2024)
Abstract Chronic alcohol exposure increases liver damage such as lipid accumulation and hepatitis, resulting in hepatic cirrhosis. Chronic alcohol intake is known to disturb circadian rhythms in humans and animals. DEC1, a basic helix-loop-helix tran
Externí odkaz:
https://doaj.org/article/d67a6ae718cd4d9395de3db05351f6aa
Autor:
Bin Tong, Yaoqi Ba, Zhengyang Li, Caidi Yang, Kangtai Su, Haodong Qi, Deju Zhang, Xiao Liu, Yuting Wu, Yixuan Chen, Jitao Ling, Jing Zhang, Xiaoping Yin, Peng Yu
Publikováno v:
Neurobiology of Disease, Vol 196, Iss , Pp 106505- (2024)
Alzheimer's and Parkinson's diseases are two of the most frequent neurological diseases. The clinical features of AD are memory decline and cognitive dysfunction, while PD mainly manifests as motor dysfunction such as limb tremors, muscle rigidity ab
Externí odkaz:
https://doaj.org/article/77b76ea39b2d42e69c8028588339a076
Autor:
Aliakbar Hasankhani, Abolfazl Bahrami, Bahareh Tavakoli-Far, Setare Iranshahi, Farnaz Ghaemi, Majid Reza Akbarizadeh, Ali H. Amin, Bahman Abedi Kiasari, Alireza Mohammadzadeh Shabestari
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/3436fae9ec2d436fb15c8f55da810e62
Autor:
Anna Skoczyńska, Monika Ołdakowska, Agnieszka Dobosz, Rajmund Adamiec, Sofya Gritskevich, Anna Jonkisz, Arleta Lebioda, Joanna Adamiec-Mroczek, Małgorzata Małodobra-Mazur, Tadeusz Dobosz
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 786 (2024)
This year marks the 35th anniversary of Professor Walter Wahli’s discovery of the PPARs (Peroxisome Proliferator-Activated Receptors) family of nuclear hormone receptors. To mark the occasion, the editors of the scientific periodical Biomolecules d
Externí odkaz:
https://doaj.org/article/c2d6d984399a49b793d19e17c616a913
Publikováno v:
Foods, Vol 13, Iss 14, p 2227 (2024)
The beneficial effects of probiotics for the improvement of metabolic disorders have been studied intensively; however, these effects are evident in a probiotic strain-specific and disease-specific manner. Thus, it is still essential to evaluate the
Externí odkaz:
https://doaj.org/article/c675a1920bbc46ed995bb15545bfd9a4
Publikováno v:
PeerJ, Vol 12, p e17082 (2024)
Background Peroxisome proliferator-activated receptors (PPARs) exert multiple functions in the initiation and progression of stomach adenocarcinomas (STAD). This study analyzed the relationship between PPARs and the immune status, molecular mutations
Externí odkaz:
https://doaj.org/article/2bf76a3bed12475c961396e27642a096
Autor:
Kendall H. Burks, Yan Xie, Michael Gildea, In-Hyuk Jung, Sandip Mukherjee, Paul Lee, Upasana Pudupakkam, Ryan Wagoner, Ved Patel, Katherine Santana, Arturo Alisio, Ira J. Goldberg, Brian N. Finck, Edward A. Fisher, Nicholas O. Davidson, Nathan O. Stitziel
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 2, Pp 100500- (2024)
Angiopoietin-like protein 3 (ANGPTL3) is a hepatically secreted protein and therapeutic target for reducing plasma triglyceride-rich lipoproteins and low-density lipoprotein (LDL) cholesterol. Although ANGPTL3 modulates the metabolism of circulating
Externí odkaz:
https://doaj.org/article/0bbb8760625945f68aa390901c0e6cd2
SLC27A2 mediates FAO in colorectal cancer through nongenic crosstalk regulation of the PPARs pathway
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Peroxisome proliferator activated receptors (PPARs) are a nuclear hormone receptors superfamily that is closely related to fatty acid (FA) metabolism and tumor progression. Solute carrier family 27 member 2 (SLC27A2) is important
Externí odkaz:
https://doaj.org/article/8d6421a87f5349bc9d62c9fa6cf6db0e