Zobrazeno 1 - 10
of 3 082
pro vyhledávání: '"PPAR- γ"'
Publikováno v:
Beni-Suef University Journal of Basic and Applied Sciences, Vol 13, Iss 1, Pp 1-12 (2024)
Abstract Background Insulin resistance (IR) leads to various metabolic abnormalities, including diabetes mellitus, obesity, nonalcoholic steatohepatitis, and neurodegenerative disorders. Natural products rich in nontoxic phytochemicals are cost-effec
Externí odkaz:
https://doaj.org/article/4550d28ef94a442285e342ef27a62817
Autor:
Sonia Burgaz, Elisa Navarro, Santiago Rodríguez-Carreiro, Carmen Navarrete, Martin Garrido-Rodríguez, Isabel Lastres-Becker, Julia Chocarro, José L. Lanciego, Eduardo Muñoz, Javier Fernández-Ruiz
Publikováno v:
Behavioral and Brain Functions, Vol 20, Iss 1, Pp 1-16 (2024)
Abstract Background The cannabigerol derivative VCE-003.2, which has activity at the peroxisome proliferator-activated receptor-γ has afforded neuroprotection in experimental models of Parkinson’s disease (PD) based on mitochondrial dysfunction (6
Externí odkaz:
https://doaj.org/article/6f04604da77847c5b5d33be525f30c82
Autor:
Shengzi Jin, Yingce Zheng, Ding Li, Xingyao Liu, Tingting Zhu, Shuang Wang, Zhonghua Liu, Yun Liu
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-18 (2024)
Abstract Obesity is an important risk factor for breast cancer in women before and after menopause. Adipocytes, key mediators in the tumor microenvironment, play a pivotal role in the relationship between obesity with cancer. However, the potential o
Externí odkaz:
https://doaj.org/article/d747ce7a28564906b21eab1d902a7e7f
Autor:
Feng Xu, Jingyi Hu, Yanan Li, Cheng Cheng, Ryan Au, Yiheng Tong, Yuguang Wu, Yuan Cui, Yulai Fang, Hongxin Chen, Lei Zhu, Hong Shen
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-20 (2024)
Abstract Background Qin-Yu-Qing-Chang decoction (QYQC), an herbal formula from China, is extensively employed to manage ulcerative colitis (UC) and exhibits potential benefits for colonic function. Nevertheless, the fundamental molecular mechanisms o
Externí odkaz:
https://doaj.org/article/7ceed583b0a4453ba50a8fac98ab79b2
Publikováno v:
Nutrition & Metabolism, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Background Breast cancer is the most diagnosed cancer in women. Its pathogenesis includes several pathways in cancer proliferation, apoptosis, and metastasis. Some clinical data have indicated the association between coffee consumption and d
Externí odkaz:
https://doaj.org/article/f9e33028a2eb4691ba67e8a61539e4a9
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Intervertebral disc degeneration (IVDD) is a common spine disease with inflammation as its main pathogenesis. Mulberroside A (MA), isolated from herbal medicine, possesses anti-inflammatory characteristics in many diseases. Wherea
Externí odkaz:
https://doaj.org/article/5cb758c4649c4be2bb331a1ffa20d9a9
Publikováno v:
Open Chemistry, Vol 22, Iss 1, Pp 1001-33 (2024)
We developed a contemporary cardioprotective medication using silver nanoparticles (AgNPs) loaded with Spinacia oleracea to treat isoproterenol (ISO)-induced myocardial infarction in mice, focusing on the PPAR-γ/NF-κB pathway. The physicochemical t
Externí odkaz:
https://doaj.org/article/77bb35a43d564fd49c1bb4354d13e6b6
Autor:
Tan Lijuan
Publikováno v:
Open Chemistry, Vol 22, Iss 1, Pp 197-210 (2024)
A modern cardioprotective drug was created by utilizing zinc nanoparticles (ZnNPs) containing curcumin to address isoproterenol-induced myocardial infarction in mice, with a specific focus on the PPAR-γ/NF-κB pathway. During the in vivo study, mice
Externí odkaz:
https://doaj.org/article/e9af06260078483493c831cdeb3033e2
Autor:
Dali Han, Bin Xiong, Xiangxiang Zhang, Chaohu Chen, Zhiqiang Yao, Hao Wu, Jinlong Cao, Jianpeng Li, Pan Li, Zhiping Wang, Junqiang Tian
Publikováno v:
Hereditas, Vol 161, Iss 1, Pp 1-13 (2024)
Abstract Purpose This study aims to reveal the relationship between AMIGO2 and proliferation, migration and tumorigenicity of bladder cancer, and explore the potential molecular mechanisms. Methods The expression level of AMIGO2 is measured by qRT-PC
Externí odkaz:
https://doaj.org/article/1ad525b9951c4b60be000f8a8f243989
Autor:
Ghadeer M. Albadrani, Ahmed E. Altyar, Osama A. Kensara, Mohie A.M Haridy, Amany A. Sayed, Zuhair M. Mohammedsaleh, Muath Q. Al-Ghadi, Rasha Mohammed Saleem, Mohamed M. Abdel-Daim
Publikováno v:
Renal Failure, Vol 46, Iss 2 (2024)
5-Fluorouracil (5-FU) is one of the most used anticancer drugs. However, its nephrotoxicity-associated drawback is of clinical concern. Lycopene (LYC) is a red carotenoid with remarkable anti-inflammatory and anti-oxidative properties. In this study,
Externí odkaz:
https://doaj.org/article/d720a68a34cb470cbbe8b7cf6b26653f