Zobrazeno 1 - 10
of 50
pro vyhledávání: '"PPARα, peroxisome proliferator activated receptor alpha"'
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription factor that is involved in lipid metabolism of various tissues. Different metabolites of fatty acids and agonists like fibrates activate PPARα for its transac
Externí odkaz:
https://doaj.org/article/e5e32ccbf9f9495397f0133a41329091
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
The nutrient sensing nuclear receptor peroxisome proliferator-activated receptor-α (PPARα) regulates the host response to short-term fasting by inducing hepatic transcriptional programming of ketogenesis, fatty acid oxidation and transport, and aut
Externí odkaz:
https://doaj.org/article/8f2c2982b4484a6898eabbdb9134805f
Autor:
Banrida Wahlang, Monika Thapa, Michael L. Merchant, Jian Jin, Sudhir Srivastava, Josiah E. Hardesty, Russell A. Prough, Shesh N. Rai, Matthew C. Cave, Kimberly Z. Head
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3806-3819 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Dioxin-like molecules have been associated with endocrine disruption and liver disease. To better understand aryl hydrocarbon receptor (AHR) biology, metabolic phenotyping and liver proteomics were performed in mice following ligand-activation or who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd0117be990219f236c36406e5afea7
https://doi.org/10.1016/j.apsb.2021.10.014
https://doi.org/10.1016/j.apsb.2021.10.014
Publikováno v:
Current Research in Food Science, Vol 4, Iss, Pp 175-181 (2021)
Current Research in Food Science
Current Research in Food Science
Collagen hydrolysate has various beneficial effects, such as bone strengthening, joint/skin protection and lipid metabolism regulation. In this study, the anti-obesity activity of ginger protease-degraded collagen hydrolysate (GDCH) was evaluated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f3dfa4c134c72c857a38bc24789065
http://www.sciencedirect.com/science/article/pii/S2665927121000162
http://www.sciencedirect.com/science/article/pii/S2665927121000162
Autor:
Yatrik M. Shah, Shogo Takahashi, Sadeesh K. Ramakrishnan, Raja Gopal Reddy Mooli, Frank J. Gonzalez, Sumeet Solanki, Jessica Rodriguez
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 585-597 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Fatty liver or nonalcoholic fatty liver disease (NAFLD) is the most common liver disease associated with comorbidities such as insulin resistance and cardiovascular and metabolic diseases. Chronic activation of hypoxic signaling, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d8ab9d3e6c8736a8ba6e7154654a18
https://doi.org/10.1016/j.jcmgh.2021.03.011
https://doi.org/10.1016/j.jcmgh.2021.03.011
Autor:
Pingping Luo, Rui Zhang, Qian Yu, George L. Tipoe, Ming Zheng, Xiaoming Sun, Yingxia Liu, Jia Xiao, Wei Li, Hong Zhang
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 668-679 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 668-679 (2021)
Alcoholic liver disease (ALD) causes insulin resistance, lipid metabolism dysfunction, and inflammation. We investigated the protective effects and direct regulating target of S-allylmercaptocysteine (SAMC) from aged garlic on liver cell injury. A ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71348640a2921fa24860e2b42b33f51
http://europepmc.org/articles/PMC7982498
http://europepmc.org/articles/PMC7982498
Autor:
Nesrin Kartal Ozer, Tugce Demirel-Yalciner, Ceren Avcilar, Tuna Felix Samanci, Dyana Sari, Erdi Sozen
Publikováno v:
Metabolism Open
Metabolism Open, Vol 12, Iss, Pp 100138-(2021)
Metabolism Open, Vol 12, Iss, Pp 100138-(2021)
Objective Increased fatty acid and triglyceride synthesis in liver, majorly modulated by Sterol Regulator Elementing Binding Protein 1c (SREBP1c), is one of the main features of non-alcoholic fatty liver disease (NAFLD). In the present study, we aime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4eac64c79cf8a24a6a6c574d5fc176f
https://pubmed.ncbi.nlm.nih.gov/34704008
https://pubmed.ncbi.nlm.nih.gov/34704008
Autor:
Tirthadipa Pradhan-Sundd
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1199-1201 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1199-1201 (2021)
Background & Aims cAMP responsive element-binding protein 3 like 3 (CREB3L3) is a membrane-bound transcription factor involved in the maintenance of lipid metabolism in the liver and small intestine. CREB3L3 controls hepatic triglyceride and glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b659cdeaf5713387b2f5a214c940ddf
https://doi.org/10.1016/j.jcmgh.2021.01.002
https://doi.org/10.1016/j.jcmgh.2021.01.002
Autor:
Liming Chen, Junjie Zhu, Lirong Zhang, Xiaochao Ma, Xueyan Shao, Pei Wang, Xiao-bo Zhong, Yifan Bao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 171-185 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The prevalence of obesity-associated conditions raises new challenges in clinical medication. Although altered expression of drug-metabolizing enzymes (DMEs) has been shown in obesity, the impacts of obese levels (overweight, obesity, and severe obes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94cf0a5fdc606267df866d8be623f019
http://www.sciencedirect.com/science/article/pii/S2211383519308585
http://www.sciencedirect.com/science/article/pii/S2211383519308585
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 805-815 (2020)
Toxicology Reports, Vol 7, Iss, Pp 805-815 (2020)
MicroRNAs (miRNAs) are short non-coding RNA species that play key roles in post-transcriptional regulation of gene expression. MiRNAs also serve as a promising source of early biomarkers for different environmental exposures and health effects, altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ed6501d212ec2b41bf3e7600201d9f
https://doi.org/10.1016/j.toxrep.2020.06.006
https://doi.org/10.1016/j.toxrep.2020.06.006