Zobrazeno 1 - 10
of 172
pro vyhledávání: '"PPAR, peroxisome proliferator–activated receptor"'
Autor:
Hygor N. Araujo, Ariclécio Cunha de Oliveira, Regina de Jesus das Neves, Tanes I. Lima, Renata Prado Vasconcelos, Paula Alexandre de Freitas, Keciany Alves de Oliveira, Marina Gabrielle Guimarães de Almeida, André Gustavo de Oliveira, Márcio V. Ramos, Leonardo R. Silveira, Bianca Cristine Favero-Santos, Dimitrius Santiago P.S.F. Guimarães
Publikováno v:
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 29, Iss 9, Pp 1061-1069 (2021)
Saudi Pharmaceutical Journal, Vol 29, Iss 9, Pp 1061-1069 (2021)
The medicinal uses of Calotropis procera are diverse, yet some of them are based on effects that still lack scientific support. Control of diabetes is one of them. Recently, latex proteins from C. procera latex (LP) have been shown to promote in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589b5f0bac9dfc1fd17b68bf7d99c68a
http://europepmc.org/articles/PMC8463474
http://europepmc.org/articles/PMC8463474
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1956-1965 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1956-1965 (2021)
Graphical abstract
Highlights • “Multiblock metabolomics” elucidates the global metabolic network in a whole body. • “Multiblock metabolomics” combines LC/MS-based metabolomics with multiblock PCA. • “Multiblock metabolomics” h
Highlights • “Multiblock metabolomics” elucidates the global metabolic network in a whole body. • “Multiblock metabolomics” combines LC/MS-based metabolomics with multiblock PCA. • “Multiblock metabolomics” h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81add9a8173efa684398bfcb0e88d68b
http://europepmc.org/articles/PMC8086023
http://europepmc.org/articles/PMC8086023
Autor:
Klaudia Theresa Warzecha, Sebastian Huss, Ralf Weiskirchen, Tom Luedde, Matthias Bartneck, Marlene Kohlhepp, Christiane Koppe, Frank Tacke, Christian Trautwein, Viktor Fech
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology : CMGH 11(2), 327-347 (2020). doi:10.1016/j.jcmgh.2020.08.012
Cellular and Molecular Gastroenterology and Hepatology : CMGH 11(2), 327-347 (2020). doi:10.1016/j.jcmgh.2020.08.012
Background & aims Macrophages are key regulators of inflammation and cancer promotion in the liver, and their recruitment and activation is linked to chemokine receptor signaling. However, the exact roles of the chemokine receptors CCR2 and CCR5 for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9654bb906a6faeed56d8bb231bdb40f5
https://doi.org/10.1016/j.jcmgh.2020.08.012
https://doi.org/10.1016/j.jcmgh.2020.08.012
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1519-1539 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Nonalcoholic fatty liver disease comprises a wide spectrum of liver injuries from simple steatosis to steatohepatitis and cirrhosis. Nonalcoholic steatohepatitis (NASH) is defined when liver steatosis is associated with inflammation, hepatocyte damag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f63dcdb7df5791629395e4c7c05eb5e
http://www.sciencedirect.com/science/article/pii/S2352345X21000187
http://www.sciencedirect.com/science/article/pii/S2352345X21000187
Autor:
Anita Krnjic, Vineeta Khare, Maximilian Baumgartner, Ildiko Mesteri, Christoph Gasche, Kyle Dammann, Adrian Frick, Kristine Jimenez, Christina Gmainer, Michaela Lang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 892-907.e1 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims p21-activated kinase-1 (PAK1) belongs to a family of serine-threonine kinases and contributes to cellular pathways such as nuclear factor-κB (NF-κB), mitogen-activated protein kinase (MAPK), phosphatidylinositol 3-kinase/protein k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f65df8854ce99ea42cd0b4240cfb89f
http://www.sciencedirect.com/science/article/pii/S2352345X20301806
http://www.sciencedirect.com/science/article/pii/S2352345X20301806
Autor:
Angshuman Bagchi, Nilkanta Chowdhury, Troyee Das, Durbadal Chatterjee, Zhumur Ghosh, Gourab Das
Publikováno v:
Genomics
COVID-19 pandemic caused by SARS-CoV-2 has already claimed millions of lives worldwide due to the absence of a suitable anti-viral therapy. The CoV envelope (E) protein, which has not received much attention so far, is a 75 amino acid long integral m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a5f641f9e87e598f5454f3221bd68e
https://doi.org/10.1016/j.ygeno.2020.11.009
https://doi.org/10.1016/j.ygeno.2020.11.009
Autor:
Noreen Samad, Muhammad Fawad Rasool, Imran Imran, Saleh Abdullah Alqarni, Waseem Ashraf, Faleh Alqahtani, Abdullah F. Alasmari, Nadia Perveen, Hafsa Pervaiz, Metab Alharbi, Mohammed Mufadhe Alanazi, Salim S. Al-Rejaie
Publikováno v:
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 28, Iss 8, Pp 951-962 (2020)
Saudi Pharmaceutical Journal, Vol 28, Iss 8, Pp 951-962 (2020)
In 30% of epileptic individuals, intractable epilepsy represents a problem for the management of seizures and severely affects the patient's quality of life due to pharmacoresistance with commonly used antiseizure drugs (ASDs). Surgery is not the bes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77524232410da1af6c9e0628b17ef7b
https://doi.org/10.1016/j.jsps.2020.06.016
https://doi.org/10.1016/j.jsps.2020.06.016
Autor:
Wilhelmus J. Kwanten, Thomas Vanwolleghem, Sven Francque, Joris G. De Man, Didier G. Ebo, Mikhaïl A. Van Herck, Lucio Gama, Luisa Vonghia, Yvon Julé, Benedicte Y. De Winter, Peter Michielsen
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 467-490 (2020)
Cellular and Molecular Gastroenterology and Hepatology
CMGH Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
CMGH Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Nonalcoholic steatohepatitis (NASH) is a multisystem condition, implicating liver and adipose tissue. Although the general involvement of the innate and adaptive immune system has been established, we aimed to define the exact role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3587864325dee2b963de9537da0ace46
http://www.sciencedirect.com/science/article/pii/S2352345X20300606
http://www.sciencedirect.com/science/article/pii/S2352345X20300606
Autor:
James E. Goldman, Alice Tang, Michelle L. Olsen, Natasha L. Pacheco, Jiangtao Li, Daniel Flint, Brett S. Phinney, Anthony W. Herren, Fatima Khan, Michael R. Heaven
Publikováno v:
Molecular & cellular proteomics : MCP, vol 21, iss 1
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics : MCP
Alexander disease (AxD) is a rare and fatal neurodegenerative disorder caused by mutations in the gene encoding glial fibrillary acidic protein (GFAP). In this report, a mouse model of AxD (GFAPTg;Gfap+/R236H) was analyzed that contains a heterozygou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27db73f1a1ae5cb5705d0a860adbda89
https://hdl.handle.net/10919/111277
https://hdl.handle.net/10919/111277
Autor:
Marlena C. Kruger, Frances M. Wolber, Hong (Sabrina) Tian, Matthew R. Miller, Parkpoom Siriarchavatana
Publikováno v:
Bone Reports
Bone Reports, Vol 15, Iss, Pp 101132-(2021)
Bone Reports, Vol 15, Iss, Pp 101132-(2021)
The osteoclast-dependent bone resorption process is a crucial part of the bone regulatory system. The excessive function of osteoclasts can cause diseases of bone, joint, and other tissues such as osteoporosis and osteoarthritis. Greenshell mussel oi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::804982a1fe1106d3242e9a1f1ddc0d62
http://europepmc.org/articles/PMC8493498
http://europepmc.org/articles/PMC8493498