Zobrazeno 1 - 10
of 144
pro vyhledávání: '"PP2B"'
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 218, Iss , Pp 112300- (2021)
In recent years, frequent hexavalent chromium [Cr(VI)] pollution incidents have severely damaged the ecology and endangered the public health. It is well known that cell senescence could promote the carcinogenesis, thus the related research on the oc
Externí odkaz:
https://doaj.org/article/a128370a73a5430a8c7f79c73ddc6848
Akademický článek
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Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
In mammals, motility and fertilizing ability of spermatozoa develop during their passage through the epididymis. After ejaculation, sperm undergo capacitation and hyperactivation in the female reproductive tract – a motility transition that is requ
Externí odkaz:
https://doaj.org/article/f966ee9c119c46ed8b6944906267a329
Publikováno v:
Biotechnology Reports, Vol 11, Iss C, Pp 86-89 (2016)
Protein phosphatase 2A (PP2A) is an enzyme useful for detecting several natural toxins represented by okadaic acid and microcystins. We found that the production of the recombinant human PP2A catalytic subunit (rhPP2Ac) in High Five insect cells coul
Externí odkaz:
https://doaj.org/article/c295485fb05049e38d3d85ad4e7c458a
Autor:
Saeedah Hamdan Al-Jadani, Saad Saeed Alamri, Hani Alothaid, Jehan S. Alrahimi, Mohammed S. Aldughaim
Publikováno v:
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 1, Pp 116-124 (2021)
Saudi Journal of Biological Sciences, Vol 28, Iss 1, Pp 116-124 (2021)
Cyclic adenosine monophosphate (cAMP) and calcium ions (Ca2+) are two chemical molecules that play a central role in the stimulus-dependent secretion processes within cells. Ca2+ acts as the basal signaling molecule responsible to initiate cell secre
Autor:
Sanna, Bastiano, Brandt, Eric B., Kaiser, Robert A., Pfluger, Paul, Witt, Sandy A., Kimball, Thomas R., van Rooij, Eva, De Windt, Leon J., Rothenberg, Marc E., Tschop, Matthias H., Benoit, Stephen C., Molkentin, Jeffery D.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2006 May 01. 103(19), 7327-7332.
Externí odkaz:
https://www.jstor.org/stable/30049689
Autor:
Regêncio, Nuno Almeida
Myotonic Dystrophy type 1 (DM1) is the most common muscular dystrophy type among adults being an incurable disease with no approved treatment. The aim of the present study is to identify novel molecular targets related to protein phosphorylation alte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2292::f401248fc497626f1a8cf092e2138946
http://hdl.handle.net/10773/33821
http://hdl.handle.net/10773/33821
Autor:
Ryan B Williams, Christopher N Johnson
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11565, p 11565 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Calcineurin, also known as protein phosphatase 2B, is a heterodimeric serine threonine phosphatase involved in numerous signaling pathways. During the past 50 years, calcineurin has been the subject of extensive investigation. Many of its cellular an
Autor:
Patrick J Nygren, John D. Scott
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Phosphorylation events that occur in response to the second messenger cAMP are controlled spatially and temporally by protein kinase A (PKA) interacting with A-kinase anchoring proteins (AKAPs). Recent advances in understanding the structural basis f
Externí odkaz:
https://doaj.org/article/af9ac63da4ea4b60aebfccf0896b2019
Publikováno v:
The Journal of Biological Chemistry
The adipocyte hormone leptin regulates glucose homeostasis both centrally and peripherally. A key peripheral target is the pancreatic β-cell, which secretes insulin upon glucose stimulation. Leptin is known to suppress glucose-stimulated insulin sec