Zobrazeno 1 - 10
of 54
pro vyhledávání: '"PP2A phosphatase"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cells require major physical changes to induce a proper repartition of the DNA. Nuclear envelope breakdown, DNA condensation and spindle formation are promoted at mitotic entry by massive protein phosphorylation and reversed at mitotic exit by the ti
Externí odkaz:
https://doaj.org/article/1db396c311e24dc6bd39304b78e71159
Autor:
Lisette Lange, Matthias Marks, Jinhua Liu, Lars Wittler, Hermann Bauer, Sandra Piehl, Gabriele Bläß, Bernd Timmermann, Bernhard G. Herrmann
Publikováno v:
Biology Open, Vol 6, Iss 6, Pp 752-764 (2017)
The mouse t haplotype, a variant 20 cM genomic region on Chromosome 17, harbors 16 embryonic control genes identified by recessive lethal mutations isolated from wild mouse populations. Due to technical constraints so far only one of these, the tw5 l
Externí odkaz:
https://doaj.org/article/0b143869240a4542ac122b843eca4e74
Publikováno v:
eLife, Vol 6 (2017)
How cells coordinate growth and division is key for size homeostasis. Phosphorylation by G1-CDK of Whi5/Rb inhibitors of SBF/E2F transcription factors triggers irreversible S-phase entry in yeast and metazoans, but why this occurs at a given cell siz
Externí odkaz:
https://doaj.org/article/b0b1a531221448f28f53f5713cb61bbd
Autor:
Shuaiyun Gao, Jing Ye, Eric Gilson, Yiming Lu, Bo Wang, Waiian Leong, Cuicui Wang, Wei Xu, Xiuyun Zhai
Publikováno v:
Aging (Albany NY)
Targeting of PP2A suggests a close link to tau-related cognitive and functional declines. However, little is known about how the expression of PP2A subunits and PP2A activity are dysregulated in the course of AD, precluding any specific targeting str
Akademický článek
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Autor:
Lars Wittler, Gabriele Bläß, Sandra Piehl, Hermann Bauer, Bernhard G. Herrmann, Jinhua Liu, Lisette Lange, Bernd Timmermann, Matthias Marks
Publikováno v:
Biology Open, Vol 6, Iss 6, Pp 752-764 (2017)
Biology open 6(6), 752-764 (2017). doi:10.1242/bio.023200
Biology Open
Biology open 6(6), 752-764 (2017). doi:10.1242/bio.023200
Biology Open
The mouse t haplotype, a variant 20 cM genomic region on Chromosome 17, harbors 16 embryonic control genes identified by recessive lethal mutations isolated from wild mouse populations. Due to technical constraints so far only one of these, the tw5 l
Autor:
Tohme, Rita
The sustainable activation of the RAS/MAPK and PI3K/AKT signaling pathways in cancer is promoted by a reduction in the activity of the tumor suppressor protein phosphatase 2A (PP2A). Therefore, a novel therapeutic strategy consists of directly activa
Autor:
Ines Calabria, Judith Vinaixa, Concha Gil, Soraya Játiva, Silvia Barceló-Batllori, Martin R. Larsen, Ethel Queralt, João P. G. L. M. Rodrigues, Carolina de LaTorre, María Luisa Hernáez, Joan-Josep Bech-Serra, Barbara Baro
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Baro, B, Játiva, S, Calabria, I, Vinaixa, J, Bech-Serra, J-J, de LaTorre, C, Rodrigues, J, Hernáez, M L, Gil, C, Barceló-Batllori, S, Larsen, M R & Queralt, E 2018, ' SILAC-based phosphoproteomics reveals new PP2A-Cdc55-regulated processes in budding yeast ', GigaScience, vol. 7, no. 5, giy047 . https://doi.org/10.1093/gigascience/giy047
GigaScience
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Baro, B, Játiva, S, Calabria, I, Vinaixa, J, Bech-Serra, J-J, de LaTorre, C, Rodrigues, J, Hernáez, M L, Gil, C, Barceló-Batllori, S, Larsen, M R & Queralt, E 2018, ' SILAC-based phosphoproteomics reveals new PP2A-Cdc55-regulated processes in budding yeast ', GigaScience, vol. 7, no. 5, giy047 . https://doi.org/10.1093/gigascience/giy047
GigaScience
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
18 páginas, 5 figuras, 1 tabla
Background: Protein phosphatase 2A (PP2A) is a family of conserved serine/threonine phosphatases involved in several essential aspects of cell growth and proliferation. PP2ACdc55 phosphatase has been extensively r
Background: Protein phosphatase 2A (PP2A) is a family of conserved serine/threonine phosphatases involved in several essential aspects of cell growth and proliferation. PP2ACdc55 phosphatase has been extensively r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e49adbe03cb62da24c3b0b0fc26b71b
http://hdl.handle.net/10261/272296
http://hdl.handle.net/10261/272296
Akademický článek
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Autor:
Lange, Lisette
t haplotypes are naturally occurring variants of a 40 Mb region on the proximal portion of mouse chromosome 17 which can affect embryonic development, among other things. The tw18 haplotype carries a lethal factor which causes defects in cell lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4732::03caa4ab3e34c84fb08986f75e207a90
https://refubium.fu-berlin.de/handle/fub188/3772
https://refubium.fu-berlin.de/handle/fub188/3772