Zobrazeno 1 - 10
of 132
pro vyhledávání: '"POU2F3"'
Autor:
Masahito Hoki, Yosuke Yamada, Emi Hiratomo, Masahiro Hirata, Yasuhide Takeuchi, Masayoshi Yoshimatsu, Masahiro Kikuchi, Yo Kishimoto, Alexander Marx, Hironori Haga
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Purpose Salivary gland tumors are histologically diverse. Ionocytes and tuft cells, rare epithelial cells found in normal salivary glands, might be associated with salivary tumors. Here, we explored the expression of FOXI1 and POU2F3, master
Externí odkaz:
https://doaj.org/article/2769009017f14cae9bddb7ad1f381866
Autor:
Sehhoon Park, Tae Hee Hong, Soohyun Hwang, Simon Heeke, Carl M. Gay, Jiyeon Kim, Hyun-Ae Jung, Jong-Mu Sun, Jin Seok Ahn, Myung-Ju Ahn, Jong Ho Cho, Yong Soo Choi, Jhingook Kim, Young Mog Shim, Hong Kwan Kim, Lauren Averett Byers, John V. Heymach, Yoon-La Choi, Se-Hoon Lee, Keunchil Park
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105062- (2024)
Summary: Background: Recent studies have reported the predictive and prognostic value of novel transcriptional factor-based molecular subtypes in small-cell lung cancer (SCLC). We conducted an in-depth analysis pairing multi-omics data with immunohis
Externí odkaz:
https://doaj.org/article/40a1e82c84034502bbbe4835972d5109
Autor:
Yosuke Yamada, Ronald Simon, Kosuke Iwane, Yuki Nakanishi, Yasuhide Takeuchi, Akihiko Yoshizawa, Masahiro Takada, Masakazu Toi, Hironori Haga, Alexander Marx, Guido Sauter
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Breast cancer is highly heterogeneous, suggesting that small but relevant subsets have been under-recognized. Rare and mainly triple-negative breast cancers (TNBCs) were recently found to exhibit tuft cell-like expression profiles
Externí odkaz:
https://doaj.org/article/225b014910d4434f9d384100f9d89699
Akademický článek
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Autor:
Shinji Matsui, Tomohiro Haruki, Yuki Oshima, Yoshiteru Kidokoro, Tomohiko Sakabe, Yoshihisa Umekita, Hiroshige Nakamura
Publikováno v:
Thoracic Cancer, Vol 13, Iss 8, Pp 1184-1192 (2022)
Abstract Background Small cell lung cancer (SCLC) is a progressive disease with a poor prognosis. Recently, a method to classify SCLC by the expression status of four transcription factors, ASCL1, NEUROD1, POU2F3, and YAP1, was proposed. Here, we inv
Externí odkaz:
https://doaj.org/article/182d2b795bce4f368ff77bc880907189
Autor:
Yu-Qing Chen, Ling-Ling Gao, Ling-Cong Kong, Xu-Hui Guan, Huan Yang, Yu-Fa Li, Zhi-Yi Lv, Xu-Chao Zhang, Hui-Ying Liang, Hua-Jun Chen, Yi-Long Wu, Jie Huang, Jin-Ji Yang
Publikováno v:
Cancer Treatment and Research Communications, Vol 35, Iss , Pp 100684- (2023)
Introduction: Recently, several clinical trials of immunotherapy for extensive-stage small-cell lung cancer (ES-SCLC) have shown limited benefits because of unselected patients. Thus, we aimed to explore whether YES-associated protein 1 (YAP-1) and P
Externí odkaz:
https://doaj.org/article/34561e2ac920400c816763499ae46027
Clinical characteristics and patient outcomes of molecular subtypes of small cell lung cancer (SCLC)
Autor:
Xiao-Long Ding, Yi-Ge Su, Liang Yu, Zhou-Lan Bai, Xue-Hong Bai, Xiao-Zhen Chen, Xia Yang, Ren Zhao, Jin-Xi He, Yan-Yang Wang
Publikováno v:
World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-8 (2022)
Abstract Background Recent studies have shown that according to the expression levels of achaete-scute homolog 1 (ASCL1), neurogenic differentiation factor 1 (NEUROD1), and POU class 2 homeobox 3 (POU2F3), small cell lung cancer (SCLC) can be divided
Externí odkaz:
https://doaj.org/article/3b3754f58f784780bf07ba59aa65c4ef
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Tuft cells are solitary chemosensory epithelial cells with microvilli at the top, which are found in hollow organs such as the gastrointestinal tract, pancreas, and lungs. Recently, an increasing number of studies have revealed the chemotactic abilit
Externí odkaz:
https://doaj.org/article/b4b47a4750544261872cd9e5d4f8d626
Akademický článek
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