Zobrazeno 1 - 10
of 6 934
pro vyhledávání: '"POSACONAZOLE"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Posaconazole enteric-coated tablet and oral suspension are two oral drugs in the treatment of invasive fungal infections (IFIs). This study compared the effectiveness and safety between posaconazole enteric-coated tablet and oral suspension,
Externí odkaz:
https://doaj.org/article/253fa50409894209b4ea9244d3bf1a3e
Autor:
Fereshteh Bayat, Ali Hashemi Baghi, Zahra Abbasian, Simin Dadashzadeh, Reza Aboofazeli, Azadeh Haeri
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-21 (2024)
Abstract Posaconazole (PCZ) is a triazole antifungal agent with a broad-spectrum activity. Our research aims to present a novel approach by combining a 2-level fractional factorial design and machine learning to optimize both chromatography and extra
Externí odkaz:
https://doaj.org/article/407dd3e046ea47f1a1181cd31fa20706
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Background Tracheobronchial mucormycosis is a fatal opportunistic infection that mainly causes airway stenosis and is difficult to manage clinically. Case presentation We report a case of severe tracheal stenosis caused by tracheobronchial m
Externí odkaz:
https://doaj.org/article/69bc7150809549fcac2cd64d54f42123
Autor:
Tomofumi Nakamura, Tatsuya Yoshinouchi, Mayu Okumura, Toshiro Yokoyama, Daisuke Mori, Hirotomo Nakata, Jun-ichirou Yasunaga, Yasuhito Tanaka
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Exophiala dermatitidis (E. dermatitidis), which causes skin or respiratory disease, is occasionally fatal in immunocompromised patients. Here, we report the unique antifungal potency of terbinafine (TRB), which targets squalene epoxidase, ag
Externí odkaz:
https://doaj.org/article/1807ecf111db414f81574022a69c9a96
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundPosaconazole is a potent antifungal agent widely used to manage invasive fungal infections, especially in immunocompromised individuals. Achieving optimal therapeutic concentrations of posaconazole can be challenging due to interpatient var
Externí odkaz:
https://doaj.org/article/c1168bebc9ee48f8b3df05c7a1e5474d
Autor:
Varsha Vivek Manade, Megha R. Kotecha
Publikováno v:
Journal of Family Medicine and Primary Care, Vol 13, Iss 9, Pp 3730-3734 (2024)
Background: The aim of the study was to describe the epidemiology and study the risk factors, clinical presentation, management, and outcome of rhino-orbital-cerebral mucormycosis (ROCM) in terms of mortality, exenteration, eye salvage, and vision sa
Externí odkaz:
https://doaj.org/article/00f483aaa1cb4e0aa8b33d12c2e4b65e
Publikováno v:
Journal of Pediatric Research, Vol 11, Iss 3, Pp 185-188 (2024)
All-trans retinoic acid (ATRA), a derivative of vitamin A, has dramatically altered the treatment landscape for acute promyelocytic leukemia (APL). APL is characterized by the abnormal maturation of myeloid cells, which become arrested at the promyel
Externí odkaz:
https://doaj.org/article/906355b70e864180a4ea52df31bfa528
Publikováno v:
Journal of Applied Pharmaceutical Research, Vol 12, Iss 4, Pp 54-65 (2024)
Background: Oteseconazole is a new molecule launched for human treatment. However, the information is not available in the public domain for analyzing blood samples. This study describes the method development and validation using LC-MS/MS to measure
Externí odkaz:
https://doaj.org/article/3f7d38979fb64a78b08ee572bba2bae7
Autor:
Yi-Shuo Shu, Zhong-Hua Dong, Yi-Lei Yang, Si-Wen Li, Qiao-Yan Yi, Peng Wang, Yin-Ping Shi, Ying-Ying Zhang, Hai-Yan Shi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract To establish a population pharmacokinetic (PopPK) model of posaconazole suspension in Chinese hematopoietic stem cell transplantation (HSCT) patients and to recommend an optimal dosing regimen. A single-center, retrospective, model-based stu
Externí odkaz:
https://doaj.org/article/b2880022308a43af92690b682e17c152
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
BackgroundVoriconazole, isavuconazole, and amphotericin (AmB) formulations are currently recommended to treat invasive pulmonary aspergillosis (IPA). We aimed to estimate the efficacy of different antifungal drugs in the initial treatment of IPA.Meth
Externí odkaz:
https://doaj.org/article/7ebf1a5413d446bf98f4e8e1eb47eb3e