Zobrazeno 1 - 10
of 2 001
pro vyhledávání: '"PNPLA3"'
Publikováno v:
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, Vol 30, Iss 4, Pp 43-51 (2024)
Introduction. Non-alcoholic fatty liver disease in most cases is closely associated with diseases such as obesity and type 2 diabetes mellitus, however, this dependence is not observed in a number of patients. In this case, hereditary factors, such a
Externí odkaz:
https://doaj.org/article/cd7881b80a8c40409068b499ac4308a1
Autor:
Kalliopi Azariadis, Nikolaos K. Gatselis, Aggeliki Lyberopoulou, Pinelopi Arvaniti, Kalliopi Zachou, Stella Gabeta, George N. Dalekos
Publikováno v:
Journal of Translational Autoimmunity, Vol 9, Iss , Pp 100243- (2024)
Background: Autoimmune hepatitis (AIH) is a relatively rare autoimmune disease with a strong genetic background. The patatin-like phospholipase domain-containing protein 3 (PNPLA3) I148 M (rs738409 C/G) variant has been associated with hepatic inflam
Externí odkaz:
https://doaj.org/article/9879f651a9064146aa0beb79728165c7
Akademický článek
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Autor:
Roger Bentanachs, Lluïsa Miró, Rosa M. Sánchez, Patricia Ramírez-Carrasco, Concepció Amat, Marta Alegret, Anna Pérez, Núria Roglans, Juan C. Laguna
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117067- (2024)
Background and aims: Drugs resolving steatotic liver disease (SLD) could prevent the evolution of metabolic dysfunction associated SLD (MASLD) to more aggressive forms but must show not only efficacy, but also a high safety profile. Repurposing of dr
Externí odkaz:
https://doaj.org/article/5df01807c6744dbc8f567596638bf3f0
Autor:
Tomotaka Mori, Eisuke Ozawa, Ryu Sasaki, Akane Shimakura, Kosuke Takahashi, Yoko Kido, Yasuko Kanda, Satoshi Matsuo, Kazuaki Tajima, Asami Beppu, Yasuhiko Nakao, Masanori Fukushima, Masafumi Haraguchi, Satoshi Miuma, Hisamitsu Miyaaki, Tomohiko Adachi, Susumu Eguchi, Shinji Okano, Kazuhiko Nakao
Publikováno v:
JGH Open, Vol 8, Iss 6, Pp n/a-n/a (2024)
Abstract Aim After pancreaticoduodenectomy, 20–40% of patients develop steatotic liver disease (SLD), and steatohepatitis can be a problem. Although patatin‐like phospholipase domain‐containing 3 protein (PNPLA3) and transmembrane 6 superfamily
Externí odkaz:
https://doaj.org/article/bda34458d9a841d689662936393d9a2d
Publikováno v:
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 33, Iss 4, Pp 30-37 (2023)
Aim: to determine the frequency of PNPLA3 rs738409 C>G gene polymorphism, leading to p.I148M substitution, in patients with non-alcoholic fatty liver disease (NAFLD), and to reveal the association between polymorphism and probable NAFLD outcomes: liv
Externí odkaz:
https://doaj.org/article/48cbf667932146ba859f3ef3fd7e827c
Akademický článek
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Autor:
Saumya Madushani Samarasinghe, Asanka Sudeshini Hewage, Rohan Chaminda Siriwardana, Kamani Hemamala Tennekoon, Madunil Anuk Niriella, Sumadee De Silva
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease showing a rising prevalence globally. Genetic predisposition plays a key role in the development and progression of the disease pathogenicity. Main
Externí odkaz:
https://doaj.org/article/be3e9ada715d47d9a7ec78ae9adc0c5f
Autor:
Jia Liu, Wenqian Qi, Song Wang, Yonggui Zhang, Xu Wang, Derong Sun, Yanhui Xu, Jingyi Shi, Honglei Duan, Qian Zhang, Hongguang Wang, Jiangbin Wang
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-10 (2023)
Abstract Background Patients with chronic hepatitis C virus (HCV) infections differ in their risk for metabolic disorders and chronic kidney disease (CKD). The aim of this study was to investigate the effect of metabolic disorders induced by genetic
Externí odkaz:
https://doaj.org/article/25cbf2291a68460397eb300b138766d9
Autor:
Amal A. Mohamed, Rania Al Dweik, Reem A. Abdelghafour, Ahmed Ramadan, Abbas M. Abbas, Hussein H. Samir, Nashwa M. Muharram, Randa Ibrahim Ahmed Elshiha, Naglaa El-Salawy, Doaa Ghaith, Marwa K. Darwish, Soha M. Abd El Salam, Eman A. Sultan, Amina S. Soliman, Mohamed Ezz AL Arab, Ahmed Yosri Elamir, Ahmed Ali Mohamed, Al-Shaymaa A. Hassanin, Alaa Ali Mohamed Abouaggour, Wael Hafez, Mohamed M. Omran
Publikováno v:
Informatics in Medicine Unlocked, Vol 48, Iss , Pp 101513- (2024)
Background: Some anthropometric, laboratory, and genetic variations, such as patatin-like phospholipase domain-containing protein 3 (PNPLA3) genetic variants, have been associated with nonalcoholic fatty liver disease (NAFLD). Liver biopsy is the mos
Externí odkaz:
https://doaj.org/article/1148743a6c2e4714868467754f67d504