Zobrazeno 1 - 10
of 175
pro vyhledávání: '"PKS/NRPS"'
Autor:
Tao Zhang, Guowei Cai, Xiaoting Rong, Jingwen Xu, Bingya Jiang, Hao Wang, Xinxin Li, Lu Wang, Ran Zhang, Wenni He, Liyan Yu
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-13 (2022)
Abstract Background Genomic analysis indicated that the genomes of ascomycetes might carry dozens of biosynthetic gene clusters (BGCs), yet many clusters have remained enigmatic. The ascomycete genus Epicoccum, belonging to the family Didymellaceae,
Externí odkaz:
https://doaj.org/article/173c7a6f8732497b99e893edfb0f5641
Autor:
Rita Toshe, Esteban Charria-Girón, Artit Khonsanit, Janet Jennifer Luangsa-ard, Syeda Javariya Khalid, Hedda Schrey, Sherif S. Ebada, Marc Stadler
Publikováno v:
Journal of Fungi, Vol 10, Iss 1, p 69 (2024)
Fungi are known as prolific producers of bioactive secondary metabolites with applications across various fields, including infectious diseases, as well as in biological control. However, some of the well-known species are still underexplored. Our cu
Externí odkaz:
https://doaj.org/article/34f49efff9c746bc9823ef03a223e8d0
Akademický článek
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Autor:
Mohamed A. Tammam, Amr El-Demerdash
Publikováno v:
Current Research in Biotechnology, Vol 6, Iss , Pp 100145- (2023)
In this comprehensive review article, an in-depth exploration over the period from 1949 to 2023 is presented, focusing on the discovery, chemistry, biosynthesis and therapeutic potentials of pederin and related polyketides. Herein, we extensively doc
Externí odkaz:
https://doaj.org/article/fa465f2622804906aa33861ed4b6e9ec
Autor:
Javier Avalos, M. Carmen Limón
Publikováno v:
Encyclopedia, Vol 2, Iss 1, Pp 1-13 (2021)
Fungal secondary metabolites (SMs) comprise a vast collection of compounds expendable for these organisms under laboratory conditions. They exhibit enormous chemical diversity, and usually belong to four major families: terpenoids, polyketides, non-r
Externí odkaz:
https://doaj.org/article/0bba19a531cc41d1beeb25568afe7dd2
Autor:
Zhiguo Liu, Wei Li, Peng Zhang, Jie Fan, Fangbo Zhang, Caixia Wang, Shuming Li, Yi Sun, Shilin Chen, Wenbing Yin
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 11, Pp 3655-3664 (2021)
Tyrosine-decahydrofluorene derivatives feature a fused [6.5.6] tricarbocyclic core and a 13-membered para-cyclophane ether. Herein, we identified new xenoacremones A, B, and C (1−3) from the fungal strain Xenoacremonium sinensis ML-31 and elucidate
Externí odkaz:
https://doaj.org/article/caf180bc9d3845dcaaa78713066b742e
Autor:
Ganesan Govindarajan, Ziwei Yao, Zhenbin Zhou, Xiaohong Zheng, Junying Ma, Pachaiyappan Saravana Kumar, Jianhua Ju, Changli Sun
Publikováno v:
Journal of Marine Science and Engineering, Vol 11, Iss 2, p 396 (2023)
Marine symbiotic actinomycetes play a key role in drug development and their ecological niches can influence a variety of natural product biosynthesis, providing potential defensive benefits. In this study, we report the whole-genome sequence analysi
Externí odkaz:
https://doaj.org/article/d90fe5069e224818b2b03a9fd92061fe
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Filamentous fungi produce a vast amount of bioactive secondary metabolites (SMs) synthesized by e.g. hybrid polyketide synthase-nonribosomal peptide synthetase enzymes (PKS-NRPS; NRPS-PKS). While their domain structure suggests a
Externí odkaz:
https://doaj.org/article/526b20ad0c4f4b0e9e87b290da0587e8
Akademický článek
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Publikováno v:
Journal of Fungi, Vol 8, Iss 4, p 355 (2022)
Trichoderma reesei (Hypocrea jecorina) was developed as a microbial cell factory for the heterologous expression of fungal secondary metabolites. This was achieved by inactivation of sorbicillinoid biosynthesis and construction of vectors for the rap
Externí odkaz:
https://doaj.org/article/c15ec1a86dbd47999dd014647db6ffd8