Zobrazeno 1 - 10
of 1 044
pro vyhledávání: '"PKD protein"'
Akademický článek
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Autor:
Owen M. Woodward, Terry Watnick
Publikováno v:
American Journal of Kidney Diseases. 73:620-623
Akademický článek
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Autor:
Metin Avkiran, Robert S. Haworth
Publikováno v:
Biochemical Pharmacology. 62:1647-1651
Protein kinase D (PKD) is a member of the protein kinase C (PKC) superfamily with distinctive structural, enzymological and regulatory properties. Identification of the cellular function(s) of PKD has been hampered by the absence of a selective inhib
Autor:
Luca Manganelli, John R. Woollard, Thomas G. Beito, Christopher J. Ward, Bing Q. Huang, Marie C. Hogan, Peter C. Harris, Tatyana V. Masyuk, Vicente E. Torres, Rachaneekorn Tammachote, Nicholas F. LaRusso, Anatoliy I. Masyuk, M. Cristine Charlesworth, Alexey A. Leontovich, Benjamin J. Madden
Publikováno v:
Journal of the American Society of Nephrology : JASN. 20(2)
Proteins associated with autosomal dominant and autosomal recessive polycystic kidney disease (polycystin-1, polycystin-2, and fibrocystin) localize to various subcellular compartments, but their functional site is thought to be on primary cilia. PC1
Autor:
Ou G; Center for Genetics and Development and Section of Molecular and Cellular Biology, University of California at Davis, Davis, California 95616, USA., Qin H, Rosenbaum JL, Scholey JM
Publikováno v:
Current biology : CB [Curr Biol] 2005 Jun 07; Vol. 15 (11), pp. R410-1.
Publikováno v:
Current Biology. 15(11):R410-R411
Cilia play diverse roles in motility and sensory reception, and defects in their formation and function underlie cilia-related human diseases [1]. One such disease is polycystic kidney disease (PKD), a heritable nephropathy associated with defects in
Autor:
Dirkx, E.
Heart failure is one of the most common causes of death. The last few years, heart failure has been associated with metabolic changes. An example is the diabetic patient; this patient often suffers from heart problems because of too much fat absorpti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05cb81bd6f465caf29ad07f4cfda1ea
https://doi.org/10.26481/dis.20120203ed
https://doi.org/10.26481/dis.20120203ed
Publikováno v:
The Journal of Biological Chemistry
Tissue factor (TF) is the principal initiator of blood coagulation and is necessary for thrombosis. We previously reported that lysophosphatidic acid (LPA), a potent bioactive lipid, highly induces TF expression at the transcriptional level in vascul
Autor:
David C. Gershlick, Danièle Stalder
In eukaryotic cells, protein sorting is a highly regulated mechanism important for many physiological events. After synthesis in the endoplasmic reticulum and trafficking to the Golgi apparatus, proteins sort to many different cellular destinations i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f35c58dc9f52ad95e343310270ecae
https://www.repository.cam.ac.uk/handle/1810/305722
https://www.repository.cam.ac.uk/handle/1810/305722