Zobrazeno 1 - 10
of 87
pro vyhledávání: '"PKC-θ"'
Publikováno v:
Chinese Medicine, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background Ulcerative colitis (UC) is an inflammatory bowel disease that causes continuous mucosal inflammation. Anemonin is a natural molecule from the Ranunculaceae and Gramineae plants that exerts anti-inflammatory properties. This study
Externí odkaz:
https://doaj.org/article/10ab6a01bee04897a75e9005ff0101a5
Autor:
Nikolaus Thuille, Kerstin Siegmund, Victoria Klepsch, Jacqueline Schörgenhuber, Sarah Danklmaier, Michael Leitges, Gottfried Baier
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-11 (2019)
Abstract Background Protein kinase C θ has been established as an important signaling intermediate in T-effector-cell activation and survival pathways by controlling activity of the key transcription factors NF-κB and NFAT. Previous studies identif
Externí odkaz:
https://doaj.org/article/d39615c71aa645ed92348aed297e5252
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
One of the major goals in immunology research is to understand the regulatory mechanisms that underpin the rapid switch on/off of robust and efficient effector (Teff) or regulatory (Tregs) T-cell responses. Understanding the molecular mechanisms unde
Externí odkaz:
https://doaj.org/article/47501661c1fd4642b3d61a7569b43126
Autor:
Michael Leitges, Jacqueline Schörgenhuber, Sarah Danklmaier, Victoria Klepsch, Gottfried Baier, Kerstin Siegmund, Nikolaus Thuille
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-11 (2019)
Cell Communication and Signaling
Cell Communication and Signaling
Background Protein kinase C θ has been established as an important signaling intermediate in T-effector-cell activation and survival pathways by controlling activity of the key transcription factors NF-κB and NFAT. Previous studies identified an ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c18b3588a7e9a420b0adaae35a15c8
http://link.springer.com/article/10.1186/s12964-019-0466-8
http://link.springer.com/article/10.1186/s12964-019-0466-8
Autor:
Jenny Dunn, Robert D. McCuaig, Abel H. Y. Tan, Wen Juan Tu, Fan Wu, Kylie M. Wagstaff, Anjum Zafar, Sayed Ali, Himanshu Diwakar, Jane E. Dahlstrom, Elaine G. Bean, Jade K. Forwood, Sofiya Tsimbalyuk, Emily M. Cross, Kristine Hardy, Amanda L. Bain, Elizabeth Ahern, Riccardo Dolcetti, Roberta Mazzieri, Desmond Yip, Melissa Eastgate, Laeeq Malik, Peter Milburn, David A. Jans, Sudha Rao
Publikováno v:
Cancers; Volume 14; Issue 6; Pages: 1596
Protein kinase C (PKC)-θ is a serine/threonine kinase with both cytoplasmic and nuclear functions. Nuclear chromatin-associated PKC-θ (nPKC-θ) is increasingly recognized to be pathogenic in cancer, whereas its cytoplasmic signaling is restricted t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6286ca8eb16cdfceab1d4b9442c01c
https://doi.org/10.3390/cancers14061596
https://doi.org/10.3390/cancers14061596
Autor:
Zuoming eSun
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
PKC-θ is selectively enriched in T cells and specifically translocates to immunological synapse where it mediates critical T cell receptor signals required for T cell activation, differentiation and survival. T cells deficient in PKC-θ are defectiv
Externí odkaz:
https://doaj.org/article/a98953f77cc943f5a8c56a2b2d8c5210
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
Protein kinase C (PKC)-θ is a serine/threonine kinase belonging to the calcium-independent novel PKC subfamily; its expression is restricted to certain tissues and cell types, including T cells. The signals delivered from T-cell receptor (TCR) and C
Externí odkaz:
https://doaj.org/article/5d115b6f5f5749a5bd11d0bf4dab27ec
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Elissa L Sutcliffe, John Zaunders, C Mee Ling Munier, Jasmine Li, Peter J. Milburn, Abel Tan, Angelo Theodoratos, Anthony D. Kelleher, Pek Siew Lim, Stephen J. Turner, Nabila Seddiki, Sudha Rao, Chan Phetsouphanh, Vedran Brezar, Tobias Knaute, Kristine Hardy, Anjum Zafar, Marco G. Casarotto, Antonia Masch, Christopher R Sutton, Wen Juan Tu, Jenny Dunn, Robert McCuaig, Johannes Zerweck, Yin Xu
Publikováno v:
Journal of Cell Science
Memory T cells are characterized by their rapid transcriptional programs upon re-stimulation. This transcriptional memory response is facilitated by permissive chromatin, but exactly how the permissive epigenetic landscape in memory T cells integrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a31dc466d8e91b708b364b7e01da9408
https://ora.ox.ac.uk/objects/uuid:074a0cf3-c95b-4ef5-ab83-8e06b51a4b6e
https://ora.ox.ac.uk/objects/uuid:074a0cf3-c95b-4ef5-ab83-8e06b51a4b6e
