Zobrazeno 1 - 10
of 214
pro vyhledávání: '"PKA, Protein kinase A"'
Autor:
Miao Zhang, Yongcai Li, Tiaolan Wang, Yang Bi, Rong Li, Yi Huang, Renyan Mao, Qianqian Jiang, Yongxiang Liu, Dov B. Prusky
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Alternaria alternata, the casual agent of black rot of pear fruit, can sense and respond to the physicochemical cues from the host surface and form infection structures during infection. To evaluate the role of cyclic AMP-dependent protein kinase (cA
Externí odkaz:
https://doaj.org/article/9cd4122402124097ae469465ddddd5e5
Akademický článek
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Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 695-716 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Diarrhea is one of the most common illnesses and is often caused by bacterial infection. Recently, we have shown that human Na+/H+ exchanger NHE3 (hNHE3), but not non-human NHE3s, interacts with the E3 ubiquitin ligase Nedd4-2. We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d39e72e4258b61df22d22d51d780ec
https://doi.org/10.1016/j.jcmgh.2021.11.006
https://doi.org/10.1016/j.jcmgh.2021.11.006
Autor:
Niani Tiaye Bailey, Bilon Khambu, Gang Liu, Sophia Blessinger, Katherine Byrnes, Russell Scaife
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 33-49 (2022)
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 33-49 (2022)
Metabolic homeostasis requires dynamic catabolic and anabolic processes. Autophagy, an intracellular lysosomal degradative pathway, can rewire cellular metabolism linking catabolic to anabolic processes and thus sustain homeostasis. This is especiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58c0ac6db641c550d04c5a5c6ba5a1a
https://doi.org/10.1016/j.apsb.2021.07.021
https://doi.org/10.1016/j.apsb.2021.07.021
Autor:
Qilong Wang, Yanze Yang, Mei Du, Jinna Wei, Xianxian Zheng, Zhang Han, Erwei Liu, Xiumei Gao, Yuefei Wang, Patrick Kwabena Oduro
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 50-75 (2022)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling exert essential regulatory function in microbial-and onco-immunology through the induction of cytokines, primarily type I interferons. Recently, the aberrant and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eaf60046ceb32698b7a7ea7c3674b44
http://www.sciencedirect.com/science/article/pii/S2211383521001775
http://www.sciencedirect.com/science/article/pii/S2211383521001775
Publikováno v:
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 29, Iss 6, Pp 539-551 (2021)
Saudi Pharmaceutical Journal, Vol 29, Iss 6, Pp 539-551 (2021)
All physiological events in living organisms originated as specific chemical/biochemical signals on the cell surface and transmitted into the cytoplasm. This signal is translated within milliseconds–hours to a specific and unique order required to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14339e0def5699befb4d16ab07f7bd41
https://doi.org/10.1016/j.jsps.2021.04.015
https://doi.org/10.1016/j.jsps.2021.04.015
Autor:
Xian Zeng, Dianwen Ju, Jiajun Fan, Yichen Wang, Jinghui Zhang, Jingyun Luan, Kai Yin, Mingming Nie
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 609-620 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 609-620 (2021)
The Hedgehog (HH) signaling pathway plays important roles in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironment (TME). Aberrant HH signaling activation may accelerate the growth of gastrointestinal tumors and lead to tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9591fe5f71a6d93ff75c586983adcb
https://doi.org/10.1016/j.apsb.2020.10.022
https://doi.org/10.1016/j.apsb.2020.10.022
Autor:
Maya Finkel, Nufar Buchshtab, Meirav Bar-Shimon, Noga Korenfeld, Ido Goldstein, Meital Charni-Natan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 1021-1036 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Gluconeogenesis from amino acids (AAs) maintains glucose homeostasis during fasting. Although glucagon is known to regulate AA catabolism, the contribution of other hormones to it and the scope of transcriptional regulation dictatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae2cd9101a9b091bf3a2c1fa8f4cfbf
https://doi.org/10.1016/j.jcmgh.2021.04.017
https://doi.org/10.1016/j.jcmgh.2021.04.017
Autor:
Yatrik M. Shah, Shogo Takahashi, Sadeesh K. Ramakrishnan, Raja Gopal Reddy Mooli, Frank J. Gonzalez, Sumeet Solanki, Jessica Rodriguez
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 585-597 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Fatty liver or nonalcoholic fatty liver disease (NAFLD) is the most common liver disease associated with comorbidities such as insulin resistance and cardiovascular and metabolic diseases. Chronic activation of hypoxic signaling, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d8ab9d3e6c8736a8ba6e7154654a18
https://doi.org/10.1016/j.jcmgh.2021.03.011
https://doi.org/10.1016/j.jcmgh.2021.03.011
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 3861-3876 (2020)
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 3861-3876 (2020)
Graphical abstract
Highlights • Toxoplasma genome harbors at least 18 phosphodiesterases encoded by distinct genes. • Most parasite PDEs lack regulatory modules and are quite divergent from their human orthologs. • Acutely-infectious tachy
Highlights • Toxoplasma genome harbors at least 18 phosphodiesterases encoded by distinct genes. • Most parasite PDEs lack regulatory modules and are quite divergent from their human orthologs. • Acutely-infectious tachy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952729672d93971172ad6bb332f7a8ef
http://europepmc.org/articles/PMC7720076
http://europepmc.org/articles/PMC7720076