Differentiation-linked changes in tyrosine phosphorylation, functional activity, and gene expression downstream from the granulocyte- macrophage colony-stimulating factor receptor

Autor: PJ Roberts, A Khwaja, AK Lie, A Bybee, K Yong, NS Thomas, DC Linch

Publikováno v: Blood. 84:1064-1073

The HL-60 model of myeloid maturation was used to test whether changes in signaling from the granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor accompany maturation-related changes in cellular responses to GM-CSF. Receptor expression,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0cdcd9c5c3a88c9e0af3145b5f704eb1
https://doi.org/10.1182/blood.v84.4.1064.bloodjournal8441064

Isoquinolinesulfonamide protein kinase inhibitors H7 and H8 enhance the effects of granulocyte-macrophage colony-stimulating factor (GM-CSE) on neutrophil function and inhibit GM-CSF receptor internalization

Autor: A Khwaja, PJ Roberts, HM Jones, K Yong, MS Jaswon, DC Linch

Publikováno v: Blood. 76(5)

Human granulocyte-macrophage colony-stimulating factor (GM-CSF) increases neutrophil surface expression of the cellular adhesion molecule CD11b and primes the respiratory burst stimulated by the bacterial peptide f-met-leuphe (FMLP). We have examined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef11dfd01a10e4128d6c3c91b1fc9d81
https://pubmed.ncbi.nlm.nih.gov/2168226

Satisfaction with Menopause/HRT Knowledge: Does Question Position in the Questionnaire Affect Response?

Autor: M Hann, Bonnie Sibbald, PJ Roberts

Publikováno v: British Menopause Society Journal. 7:31-31

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5dfa3b644ff2086d889a5d6687b72003
https://doi.org/10.1177/13621807010070s347

Mechanism of human monocyte activation via the 40-kDa Fc receptor for IgG

Autor: Ea, Macintyre, Pj, Roberts, Abdul-Gaffar R, O'Flynn K, Gr, Pilkington, Farace F, Morgan J, Dc, Linch

Publikováno v: Europe PubMed Central

It is shown that a mAb specific for the human 40-kDa FcR (FcRII) leads to activation of human monocytic cells but that extensive cross-linking of the receptor is required. Calcium mobilization can be induced in immature monocytic cells (undifferentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8e26077213166526c436b87b8c7a5898
https://pubmed.ncbi.nlm.nih.gov/2848894

Immunoprecipitation assays for the detection of specific extractable nuclear antigen ​autoantibodies: a role in the modern immunology laboratory?

Autor: Beroukas D; Department of Immunology, SA Pathology and Flinders Medical Centre, SA, Australia; Department of Immunology, Flinders University, SA, Australia., Roberts-Thomson PJ; Department of Immunology, SA Pathology and Flinders Medical Centre, SA, Australia; Department of Immunology, Flinders University, SA, Australia., Gordon TP; Department of Immunology, SA Pathology and Flinders Medical Centre, SA, Australia; Department of Immunology, Flinders University, SA, Australia., Lee AYS; Department of Immunology, ICPMR and Westmead Hospital, NSW Health Pathology, Westmead, NSW, Australia; Centre for Immunology & Allergy Research, Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW, Australia. Electronic address: adrian.lee1@sydney.edu.au.

Publikováno v: Pathology [Pathology] 2024 Oct 15. Date of Electronic Publication: 2024 Oct 15.