Zobrazeno 1 - 10
of 86
pro vyhledávání: '"PIYU ZHAO"'
Autor:
Ana Christina L Opina, Ketan B Ghaghada, Piyu Zhao, Garry Kiefer, Ananth Annapragada, A Dean Sherry
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27370 (2011)
Lanthanide DOTA-tetraglycinate (LnDOTA-(gly)₄⁻) complexes contain four magnetically equivalent amide protons that exchange with protons of bulk water. The rate of this base catalyzed exchange process has been measured using chemical exchange satu
Externí odkaz:
https://doaj.org/article/0beb3bfdcf144c6abbc6ddf9cf8faaa6
Lanthanide-Based T2ex and CEST Complexes Provide Insights into the Design of pH Sensitive MRI Agents
Publikováno v:
Angewandte Chemie International Edition. 56:16626-16630
The CEST and T1 /T2 relaxation properties of a series of Eu3+ and Dy3+ DOTA-tetraamide complexes with four appended primary amine groups are measured as a function of pH. The CEST signals in the Eu3+ complexes show a strong CEST signal after the pH w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893ba4fc9eb4df03300982791f761aba
https://doi.org/10.1002/anie.201707959
https://doi.org/10.1002/anie.201707959
Lanthanide-Based T2ex and CEST Complexes Provide Insights into the Design of pH Sensitive MRI Agents
Publikováno v:
Angewandte Chemie. 129:16853-16857
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b9abda34daf263569d6afc02d78f11b
https://doi.org/10.1002/ange.201707959
https://doi.org/10.1002/ange.201707959
Autor:
Sara Chirayil, Namini Paranawithana, Piyu Zhao, André F. Martins, Gabriele Meloni, Veronica Clavijo Jordan, A. Dean Sherry
Publikováno v:
J Am Chem Soc
The design, synthesis, and properties of a new gadolinium-based copper-responsive magnetic resonance imaging (MRI) contrast agent is presented. The sensor (GdL(1)) has high selectivity for copper ions and exhibits a 43% increase in r(1) relaxivity (2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5236ddbf41a2fac48275bf58cce6a87a
https://europepmc.org/articles/PMC9991518/
https://europepmc.org/articles/PMC9991518/
Autor:
Yuyan Mai, André F. Martins, Lei Zhang, A. Dean Sherry, Piyu Zhao, Alexander M. Funk, Veronica Clavijo Jordan, Wei Chen, Yunkou Wu, Shanrong Zhang
Publikováno v:
Chemistry - A European Journal. 23:1752-1756
Overproduction of lactate is a hallmark of cancer, yet a method to quantitatively measure lactate production by cancer cells is not straight-forward. Chemical exchange saturation transfer magnetic resonance imaging (CEST MRI) can potentially be used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff80e634c4431ea3e5e96d37ca12283
https://doi.org/10.1002/chem.201604558
https://doi.org/10.1002/chem.201604558
Autor:
André F. Martins, Carlos Platas-Iglesias, Garry E. Kiefer, A. Dean Sherry, W. Shirangi Fernando, Piyu Zhao, Yunkou Wu
Publikováno v:
Inorganic Chemistry. 55:3007-3014
EuDOTA-tetraamide complexes as paraCEST agents offer an attractive platform for designing biological sensors and responsive agents. The early versions of these agents showed low sensitivity at temperature and power levels suitable for in vivo applica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06aa1a3ac7f9672cbe8cd223cb7b2344
https://doi.org/10.1021/acs.inorgchem.5b02850
https://doi.org/10.1021/acs.inorgchem.5b02850
Autor:
André F, Martins, Veronica, Clavijo Jordan, Filip, Bochner, Sara, Chirayil, Namini, Paranawithana, Shanrong, Zhang, Su-Tang, Lo, Xiaodong, Wen, Piyu, Zhao, Michal, Neeman, A Dean, Sherry
Publikováno v:
Journal of the American Chemical Society. 140(50)
It has been demonstrated that divalent zinc ions packaged with insulin in β-cell granules can be detected by MRI during glucose-stimulated insulin secretion using a gadolinium-based Zn(2+)-sensitive agent. This study was designed to evaluate whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2b7346f0bcd7ee2b2ed9cbb8891a811
https://pubmed.ncbi.nlm.nih.gov/30484648
https://pubmed.ncbi.nlm.nih.gov/30484648
Autor:
Namini Paranawithana, André F. Martins, Sara Chirayil, Gabriele Meloni, Dean Sherry, Veronica Clavijo-Jordan, Piyu Zhao
The design, synthesis, and properties of a new gadolinium-based copper-responsive MRI contrast agents are presented in detail here. The sensor (GdL1) has high selectivity for copper ions and exhibits a 47% increase in r1 relaxivity upon binding to 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad45de3a5eb5da2f2c11fffab1b25466
https://doi.org/10.26434/chemrxiv.7359095
https://doi.org/10.26434/chemrxiv.7359095
Autor:
Christian Preihs, Garry E. Kiefer, Jing Yu, Sara Chirayil, Khaled Nasr, André F. Martins, A. Dean Sherry, Yunkou Wu, Piyu Zhao, Veronica Clavijo Jordan
Publikováno v:
Journal of the American Chemical Society. 137:14173-14179
Given the known water exchange rate limitations of a previously reported Zn(II)-sensitive MRI contrast agent, GdDOTA-diBPEN, new structural targets were rationally designed to increase the rate of water exchange to improve MRI detection sensitivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a64b056dd0d213d5c84429ebea6b73
https://doi.org/10.1021/jacs.5b09158
https://doi.org/10.1021/jacs.5b09158
Autor:
A. Dean Sherry, André F. Martins, David Esteban-Gómez, Piyu Zhao, Michael Tieu, Lei Zhang, Carlos Platas-Iglesias, Gregory T. McCandless
A previous report demonstrated that EuDO3A could be used as an NMR shift reagent for imaging extracellular lactate produced by cancer cells using CEST imaging. In this work, a series of heptadentate macrocyclic YbDO3A-trisamide complexes with δ-chir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c47a5d6eef406584035bc04dbb4f01d
https://europepmc.org/articles/PMC5796655/
https://europepmc.org/articles/PMC5796655/