Zobrazeno 1 - 10
of 36
pro vyhledávání: '"PIP5K1α"'
Autor:
Per Flodbring Larsson, Richard Karlsson, Martuza Sarwar, Regina Miftakhova, Tianyan Wang, Azharuddin Sajid Syed Khaja, Julius Semenas, Sa Chen, Andreas Hedblom, Amjad Ali, Kristina Ekström‐Holka, Athanasios Simoulis, Anjani Kumar, Anette Gjörloff Wingren, Brian Robinson, Sun Nyunt Wai, Nigel P. Mongan, David M. Heery, Daniel Öhlund, Thomas Grundström, Niels Ødum, Jenny L. Persson
Publikováno v:
Molecular Oncology, Vol 16, Iss 13, Pp 2496-2517 (2022)
Low‐affinity immunoglobulin gamma Fc region receptor III‐A (FcγRIIIa) is a cell surface protein that belongs to a family of Fc receptors that facilitate the protective function of the immune system against pathogens. However, the role of FcγRII
Externí odkaz:
https://doaj.org/article/b9424d66238242208aa13b376f19daab
Autor:
Tianyan Wang, Martuza Sarwar, Jonathan B Whitchurch, Hilary M Collins, Tami Green, Julius Semenas, Amjad Ali, Christopher J Roberts, Ryan D Morris, Madlen Hubert, Sa Chen, Zahra El-Schich, Anette G Wingren, Thomas Grundström, Richard Lundmark, Nigel P Mongan, Lena Gunhaga, David M Heery, Jenny L Persson
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
PIP5K1α has emerged as a promising drug target for the treatment of castration-resistant prostate cancer (CRPC), as it acts upstream of the PI3K/AKT signaling pathway to promote prostate cancer (PCa) growth, survival and invasion. However, little is
Externí odkaz:
https://doaj.org/article/6f00bee0afbc4bf1a1d8d8f354c3e273
Autor:
Julius Semenas, Tianyan Wang, Azharuddin Sajid Syed Khaja, AKM Firoj Mahmud, Athanasios Simoulis, Thomas Grundström, Maria Fällman, Jenny L. Persson
Publikováno v:
Molecular Oncology, Vol 15, Iss 4, Pp 968-986 (2021)
Selective ERα modulator, tamoxifen, is well tolerated in a heavily pretreated castration‐resistant prostate cancer (PCa) patient cohort. However, its targeted gene network and whether expression of intratumor ERα due to androgen deprivation thera
Externí odkaz:
https://doaj.org/article/76e6e359dd224187a7177058d52aa91f
Akademický článek
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Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-7 (2018)
Abstract Background Skeletal muscle satellite cell-derived myoblasts are mainly responsible for postnatal muscle growth and injury-induced regeneration. Many intracellular signaling pathways are essential for myogenic differentiation, while a number
Externí odkaz:
https://doaj.org/article/bab1997051d24ae1874058460914db80
Akademický článek
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Autor:
Wang, Tianyan
Metastasis is the leading cause of cancer death because of a lack of early diagnosis tools and efficient treatment drugs. The lipid kinase phosphatidylinositol 4-phosphate 5 kinase (PIP5K1α) has been shown to play a vital role in the PI3K/AKT and KR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1fe6f7d68cba9b487161b7e1a6e3ea4f
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-193617
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-193617
Autor:
Per Flodbring Larsson, Richard Karlsson, Martuza Sarwar, Regina Miftakhova, Tianyan Wang, Azharuddin Sajid Syed Khaja, Julius Semenas, Sa Chen, Andreas Hedblom, Amjad Ali, Kristina Ekström‐Holka, Athanasios Simoulis, Anjani Kumar, Anette Gjörloff Wingren, Brian Robinson, Sun Nyunt Wai, Nigel P. Mongan, David M. Heery, Daniel Öhlund, Thomas Grundström, Niels Ødum, Jenny L. Persson
Publikováno v:
Larsson, P F, Karlsson, R, Sarwar, M, Miftakhova, R, Wang, T, Syed Khaja, A S, Semenas, J, Chen, S, Hedblom, A, Ali, A, Ekström-Holka, K, Simoulis, A, Kumar, A, Wingren, A G, Robinson, B, Nyunt Wai, S, Mongan, N P, Heery, D M, Öhlund, D, Grundström, T, Ødum, N & Persson, J L 2022, ' FcγRIIIa receptor interacts with androgen receptor and PIP5K1α to promote growth and metastasis of prostate cancer ', Molecular Oncology, vol. 16, no. 13, pp. 2496-2517 . https://doi.org/10.1002/1878-0261.13166
Low-affinity immunoglobulin gamma Fc region receptor III-A (FcγRIIIa) is a cell surface protein that belongs to a family of Fc receptors that facilitate the protective function of the immune system against pathogens. However, the role of FcγRIIIa i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efc64ef5fc6032b438dc578050a0869
https://pubmed.ncbi.nlm.nih.gov/34932854
https://pubmed.ncbi.nlm.nih.gov/34932854
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Thomas Grundström, Tianyan Wang, Julius Semenas, Athanasios Simoulis, Akm Firoj Mahmud, Jenny L. Persson, Azharuddin Sajid Syed Khaja, Maria Fällman
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 15, Iss 4, Pp 968-986 (2021)
Molecular Oncology, Vol 15, Iss 4, Pp 968-986 (2021)
In the present study, we unrevealed the effect of tamoxifen on ERα and PIP5K1α/AKT that are responsible for prostate cancer growth and invasion. Tamoxifen in combination treatment with PIP5K1α inhibitor, ISA‐2011B, led to tumor regression in xen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a769dc8f7f3ab52e117a96615dd9746e
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-177666
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-177666