Zobrazeno 1 - 10
of 1 498
pro vyhledávání: '"PIM-1"'
Autor:
Hao Zhang, Li Sheng, Jia Chen, Xiaolin Wang, Peipei Tao, Dongsheng Ren, Hao Cui, Kai Yang, Zhuozhuo Tang, Zhijun Zhang, Xiangming He, Hong Xu
Publikováno v:
Carbon Capture Science & Technology, Vol 13, Iss , Pp 100276- (2024)
Mixed-matrix membranes (MMMs) leverage the processability of polymers and selectivity of Metal-Organic Frameworks (MOFs). However, they still suffer from poor interfacial compatibility and limited scalability in preparation. In certain polymers, MOFs
Externí odkaz:
https://doaj.org/article/c1540e97ef304788aaf841618e55f871
Autor:
Marwa E. Abdelaziz, Mostafa M. M. El-Miligy, Salwa M. Fahmy, Marwa M. Abu-Serie, Aly A. Hazzaa, Mona A. Mahran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractNew aromatic O-alkyl pyridine derivatives were designed and synthesised as Proviral Integration Moloney (PIM)-1 kinase inhibitors. 4c and 4f showed potent in vitro anticancer activity against NFS-60, HepG-2, PC-3, and Caco-2 cell lines and lo
Externí odkaz:
https://doaj.org/article/e162c88d829d4fc1b977203714ab0d09
Akademický článek
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Autor:
Syed Sultan Beevi, Kavitha Anbrasu, Krishna Kiran Kannepalli, Vinod Kumar Verma, Ram Pillarisetti, Sailaja Madigubba, Radhika Chowdary Darapuneni, Bhaskar Rao Bollineni
Publikováno v:
Journal of Medical and Scientific Research, Vol 11, Iss 3, Pp 186-193 (2023)
Purpose: Breast cancer accounts for most cancer-related deaths in women with over 2.3 million new breast cancer cases diagnosed every year worldwide. Pim kinases are oncogenic proteins that play important role in various cancers. Pim-1 contains 1.7 k
Externí odkaz:
https://doaj.org/article/fe1ceac97dfb425685a00c21c71385b5
Autor:
Zhen Zhang, Shujun Xie, Jin Qian, Fengqiang Gao, Wenjian Jin, Lingqiao Wang, Lili Yan, Hao Chen, Wangxiang Yao, Maoqiang Li, Xuepeng Wang, Liulong Zhu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Osteoarthritis (OA), in which macrophage-driven synovitis is considered closely related to cartilage destruction and could occur at any stage, is an inflammatory arthritis. However, there are no effective targets to cure the progr
Externí odkaz:
https://doaj.org/article/dadb23f7fdf046019da150fe9cffb661
Autor:
Mostafa M. M. El-Miligy, Marwa E. Abdelaziz, Salwa M. Fahmy, Tamer M. Ibrahim, Marwa M. Abu-Serie, Mona A. Mahran, Aly A. Hazzaa
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
New quinoline-pyridine hybrids were designed and synthesised as PIM-1/2 kinase inhibitors. Compounds 5b, 5c, 6e, 13a, 13c, and 14a showed in-vitro low cytotoxicity against normal human lung fibroblast Wi-38 cell line and potent in-vitro anticancer ac
Externí odkaz:
https://doaj.org/article/9e34b94d9a5b4637adf59e548997a9d7
Akademický článek
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Publikováno v:
Nano Select, Vol 3, Iss 10, Pp 1395-1406 (2022)
Abstract This paper is dedicated to improve the conversion efficiency of carboxylation for polymers of intrinsic microporous (PIM‐1). According to stable thermal properties of PIM‐1, a hydrothermal method is used for the first time to achieve the
Externí odkaz:
https://doaj.org/article/2c7108b8f0364f1fb7f875d115ea03cc
Publikováno v:
Life, Vol 13, Iss 8, p 1635 (2023)
PIM-1 kinase is a serine-threonine phosphorylating enzyme with implications in multiple types of malignancies, including prostate, breast, and blood cancers. Developing better search methodologies for PIM-1 kinase inhibitors may be a good strategy to
Externí odkaz:
https://doaj.org/article/5cbf5bc0d7a5432886adf81002fb5963