Zobrazeno 1 - 10
of 42
pro vyhledávání: '"PI5P"'
Autor:
Lucia E. Rameh, Raymond D. Blind
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The accidental discovery of PI5P (phosphatidylinositol-5-phosphate) was published 25 years ago, when PIP5K type II (phosphoinositide-4-phosphate 5-kinase) was shown to actually be a 4-kinase that uses PI5P as a substrate to generate PI(4,5)P2. Conseq
Externí odkaz:
https://doaj.org/article/a9d5526e4de24bb3ba0b53e30cd709ae
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3692-3707 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3692-3707 (2021)
Graphical abstract
Highlights • YPIBP contains 679 PI-binding yeast proteins and their PI-binding evidence. • YPIBP contains 181 lipid-binding domains and 103 lipid-related domains. • YPIBP provides PI-binding enrichment analysis and domai
Highlights • YPIBP contains 679 PI-binding yeast proteins and their PI-binding evidence. • YPIBP contains 181 lipid-binding domains and 103 lipid-related domains. • YPIBP provides PI-binding enrichment analysis and domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb2a67a1c3142c2aef0b9fab10457ce
https://pubmed.ncbi.nlm.nih.gov/34285772
https://pubmed.ncbi.nlm.nih.gov/34285772
Autor:
Jacques A Nunes, Geoffrey eGuittard
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Phosphoinositides are critical regulators in cell biology. Phosphatidylinositol 4,5-bisphosphate, also known as PI(4,5)P2 or PIP2, was the first variety of phosphoinositide to enter in the T cell signaling scene. Phosphatidylinositol bis-phosphates a
Externí odkaz:
https://doaj.org/article/d483ae46d3014f21815653926d50057f
Akademický článek
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Autor:
Miguel Vicente-Manzanares, Clara Llorente-González, Jesús Baltanás-Copado, Xosé R. Bustelo, Senena Corbalán-García, Carmen Citterio, Sonia Rodríguez-Fdez, L. Francisco Lorenzo-Martín
Publikováno v:
Cells
Volume 8
Issue 12
Volume 8
Issue 12
Phosphatidylinositol&ndash
5 phosphate (PI5P) and other mono-phosphoinositides (mono-PIs) play second messenger roles in both physiological and pathological conditions. Despite this, their intracellular targets and mechanisms of action remain po
5 phosphate (PI5P) and other mono-phosphoinositides (mono-PIs) play second messenger roles in both physiological and pathological conditions. Despite this, their intracellular targets and mechanisms of action remain po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef30153667d188b326143881d72cb42
http://europepmc.org/articles/PMC6952945
http://europepmc.org/articles/PMC6952945
Autor:
Roberta Fiume, Irene Faenza, Antonio Enrico Zaurito, Nullin Divecha, Shidqiyyah Abdul-Hamid, Alessandro Poli
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2080 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2080 (2019)
Phosphatidylinositol (PI)-related signaling plays a pivotal role in many cellular aspects, including survival, cell proliferation, differentiation, DNA damage, and trafficking. PI is the core of a network of proteins represented by kinases, phosphata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbc30bbd19d2f9c831503be9cf4a0a2
http://europepmc.org/articles/PMC6539119
http://europepmc.org/articles/PMC6539119
Akademický článek
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Publikováno v:
Advances in Biological Regulation. 61:47-50
The phosphatidylinositol 5-phosphate 4-kinases (PI5P4Ks) are an important family of enzymes, whose physiological roles are being teased out by a variety of means. Phosphatidylinositol-5-phosphate 4-kinase γ (PI5P4Kγ) is especially intriguing as its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::823dadcf0544328cd58b90dfb573c8e2
Akademický článek
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Autor:
Clarke, Jonathan H., Giudici, Maria-Luisa, Burke, John E., Williams, Roger L., Maloney, David J., Marugan, Juan, Irvine, Robin F.
Publikováno v:
Biochemical Journal
NIH-12848 (NCGC00012848-02), a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor, was explored as a tool for investigating this enigmatic, low activity, lipid kinase. PI5P4K assays in vitro showed that NIH-12848 inhibited PI5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::78506b46b15674e81aa89fa00d856df2
https://www.repository.cam.ac.uk/handle/1810/246867
https://www.repository.cam.ac.uk/handle/1810/246867
