Zobrazeno 1 - 10
of 939
pro vyhledávání: '"PI3K-Akt signaling"'
Publikováno v:
Zhongguo cuzhong zazhi, Vol 19, Iss 11, Pp 1321-1332 (2024)
目的 探究肉苁蓉总苷通过激活PI3K-Akt信号通路对大鼠脑缺血再灌注损伤（cerebral ischemia-reperfusion injury，CIRI）的保护作用及机制。 方法 60只雄性Wistar大鼠随机分为假手术组、模型组、肉苁蓉
Externí odkaz:
https://doaj.org/article/332232472c094973acc7554f25889f85
Autor:
Dongqing Cui, Haixia Liu, Lili Cao, Xiaowei Du, Dingxin Liu, Zhiping Liu, Tong Wang, Hui Yang, Xiaolei Zheng, Zhaohong Xie, Shunliang Xu, Jianzhong Bi, Ping Wang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-30 (2024)
Abstract Background Alzheimer's disease (AD) is a prevalent irreversible neurodegenerative condition marked by gradual cognitive deterioration and neuronal loss. The mammalian Ste20-like kinase (MST1)–Hippo pathway is pivotal in regulating cell apo
Externí odkaz:
https://doaj.org/article/bc44250feb434892a33fd1240e06dd29
Publikováno v:
Molecular Oncology, Vol 18, Iss 9, Pp 2107-2110 (2024)
Rewiring of cellular metabolism is now fully recognized as a hallmark of cancer. Tumor cells reprogram metabolic pathways to meet the energetic and macromolecular demands to support unrestricted growth and survival under unfavorable conditions. It is
Externí odkaz:
https://doaj.org/article/4357e0c3e3124af3bb2300de6cdfa96b
Autor:
Yu-Yao Tseng
Publikováno v:
Nutrition & Metabolism, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Background Obesity is a global health concern associated with increased risk of diseases like cardiovascular conditions including ischemic heart disease, a leading cause of mortality. The ketogenic diet (KD) has potential therapeutic applica
Externí odkaz:
https://doaj.org/article/363d320dd3df44098146bccf30a62915
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 3523-3545 (2024)
Qingyang Liu,1,* Jian Wang,2,* Chunhui Ding,3 Ying Chu,1 Fengying Jiang,1 Yunxia Hu,4 Haifeng Li,2 Qiubo Wang1 1Department of Clinical Laboratory, Wuxi Ninth People’s Hospital Affiliated to Soochow University, Wuxi, Jiangsu, 214000, People
Externí odkaz:
https://doaj.org/article/f36da8a6b8f04d6d9dd5ea62c5b58fde
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
BackgroundNeuropathic pain (NeP) presents considerable challenges in terms of effective management and significantly impacts the quality of life for affected patients. The current treatment options for NeP are limited, highlighting the need for alter
Externí odkaz:
https://doaj.org/article/1f6f9ea9f6a241d39320c8b83738aeba
Autor:
Feng Li, Yilei Dong, Guangrui Wang, Zishan Huang, Wenting Song, Xiaoyu Zheng, Peng Zhang, Mingjiang Yao
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 13, Iss , Pp 100550- (2024)
Introduction: Tongluo Qingnao (TLQN) Formula is a patent Traditional Chinese Medicine injection designed for the treatment of Acute Ischemic Stroke (AIS) and associated complications. Previous researches had shown promising potential of TLQN in treat
Externí odkaz:
https://doaj.org/article/e4b360d90c6345148144307a2e99b8a7
Autor:
Lijie Lu, Chengfeng Huang, Yongfeng Zhou, Huajuan Jiang, Cuiping Chen, Jinyu Du, Tao Zhou, Feiyan Wen, Jin Pei, Qinghua Wu
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionWith the onset of the COVID-19 pandemic, the incidence and prevalence of acute pharyngitis (AP) have increased significantly. Tinosporae Radix (TR) is a vital medication utilized in the treatment of pharyngeal and laryngeal ailments, espe
Externí odkaz:
https://doaj.org/article/f849bcd8e41e4397bfaec54693d6c45c
Autor:
Clare Hsu, Jia-Hao Zeng, Long Chen, Li-Jian Chen, Xiu-Wen Li, Jian-Zheng Yang, Yi Liu, Jia-Li Liu, Jia-Hao Li, Ji-Hui Li, Xiao-Li Xie, Qi Wang
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 286, Iss , Pp 117173- (2024)
2-Ethylhexyl diphenyl phosphate (EHDPHP), a widely used organophosphorus flame retardant (OPFR), is ubiquitous in daily life because of its extensive application in plastic production. EHDPHPs, which are only superficially applied and not chemically
Externí odkaz:
https://doaj.org/article/f5f7797ec38a415488d17fe012a5bc04
Publikováno v:
Clinical, Cosmetic and Investigational Dermatology, Vol Volume 17, Pp 1637-1648 (2024)
Wei Xiang, Zhen Guo, Yiming Zhang, Yuanzhi Xu Department of Stomatology, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, People’s Republic of ChinaCorrespondence: Yuanzhi Xu; Yiming Zhang, Email amyxyz01@Hotmail
Externí odkaz:
https://doaj.org/article/ea19fbde56bb49eab7a391f449d78e69