Zobrazeno 1 - 10
of 637
pro vyhledávání: '"PI3K / Akt"'
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 2869-2881 (2024)
Benchi Cai,* Qitong Wang,* Lifan Zhong, Fang Liu, Xinyu Wang, Tao Chen Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, 570311, People’s Republic of China*These authors contributed equally to this workCorresponde
Externí odkaz:
https://doaj.org/article/2d7295b9c550448b8103541eb9f1fb42
Autor:
Yasaman Yadollahi-Farsani, Vahid Reisi Vanani, Zahra Lorigooini, Anahita Farahzad, Hossein Amini-Khoei
Publikováno v:
IBRO Neuroscience Reports, Vol 16, Iss , Pp 1-7 (2024)
Autism spectrum disorder (ASD) is a neurodegenerative disease with increasing incidence in the world. The maternal separation (MS) stress at early life with its own neuroendocrine and neurostructural changes can provide the basis for development of A
Externí odkaz:
https://doaj.org/article/69ed72de20854a0dbdc78e547f8e065d
Autor:
Masao Ryu, Takashi Yurube, Yoshiki Takeoka, Yutaro Kanda, Takeru Tsujimoto, Kunihiko Miyazaki, Hiroki Ohnishi, Tomoya Matsuo, Naotoshi Kumagai, Kohei Kuroshima, Yoshiaki Hiranaka, Ryosuke Kuroda, Kenichiro Kakutani
Publikováno v:
Cells, Vol 13, Iss 23, p 2030 (2024)
The mammalian target of rapamycin (mTOR), a serine/threonine kinase, promotes cell growth and inhibits autophagy. The following two complexes contain mTOR: mTORC1 with the regulatory associated protein of mTOR (RAPTOR) and mTORC2 with the rapamycin-i
Externí odkaz:
https://doaj.org/article/2c2946945e674ebba5f9a96aa48e8276
Autor:
Ai Tsuji, Sayuri Yoshikawa, Sae Morikawa, Yuka Ikeda, Kurumi Taniguchi, Haruka Sawamura, Tomoko Asai, Satoru Matsuda
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 3, Pp 460-473 (2023)
Immunotherapy strategies targeting immune checkpoint molecules such as programmed cell death-1 (PD-1) and cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) are revolutionizing oncology. However, its effectiveness is limited in part due to the loss
Externí odkaz:
https://doaj.org/article/3399d79b4953409dbb7f2383b3d968b9
Autor:
Mingchun Li, Zhihua Liu, Zan Hou, Xiangcai Wang, Huaqiu Shi, Yamei Li, Xuewen Xiao, Zhixian Tang, Jianqiong Yang, Yaoling Luo, Minhong Zhang, Ming Chen
Publikováno v:
Thoracic Cancer, Vol 14, Iss 14, Pp 1223-1238 (2023)
Abstract Background Zinc finger protein 687 (ZNF687) has previously been discovered as a potential oncogene in individuals with giant cell tumors of the bone, acute myeloid leukemia, and hepatocellular carcinoma. However, its role and mechanism in lu
Externí odkaz:
https://doaj.org/article/d0eab200725b4321b7c043d6fca3b6ee
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 1263-1264 (2024)
Huang Y, Chen J, Yang S, et al. Drug Des Devel Ther. 2020;14:4625–4637. We, the Editor and Publisher of the journal Drug Design, Development and Therapy, have retracted the following article. Following publication of the article, concerns were rais
Externí odkaz:
https://doaj.org/article/f0d4fee3f7fb4bcdb41cebe8d3f5f0e3
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Insulin-like growth factor-1 receptor (IGF-1R) promotes cell proliferation and migration and inhibitsapoptosis, all of which can contribute to the development of cancers. Method This study investigated the effect and mechanism of
Externí odkaz:
https://doaj.org/article/1d116acd7a3f408cbecd8ef4e9355d5d
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