Zobrazeno 1 - 10
of 1 071
pro vyhledávání: '"PI3K/Akt/mTOR signaling pathway"'
Autor:
Teng Li, Lianglin Zhang, Menghan Cheng, En Hu, Qiuju Yan, Yao Wu, Weikang Luo, Hong Su, Zhe Yu, Xin Guo, Quan Chen, Fei Zheng, Haigang Li, Wei Zhang, Tao Tang, Jiekun Luo, Yang Wang
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background Xuefu Zhuyu decoction (XFZYD) has been extensively utilized to treat traumatic brain injury (TBI). However, the bioactive compounds and the underlying mechanisms have not yet been elucidated. Objectives This study aimed to investi
Externí odkaz:
https://doaj.org/article/dc8e29be9b004d6b879d641486001145
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 6501-6519 (2024)
Zhen Wang,1,* Hui Xu,1,2,* Zheng Wang,1,* Yu Wang,3,* Jieyao Diao,1 Juntao Chen,1 Yuchen Xie,4 Lijuan Zhang,5 Miaoxiu Li,6 Yanqin Bian,7 Yunfeng Zhou1 1College of Acupuncture and Massage, Henan University of Chinese Medicine, Zhengzho
Externí odkaz:
https://doaj.org/article/7a1cd0b0f2e94db88dd2def517a61c66
Publikováno v:
Shipin gongye ke-ji, Vol 45, Iss 18, Pp 334-343 (2024)
To investigate different irradiation doses of Se-enriched A.Auricularia polysaccharide (SAAP) in type 1 diabetes mellitus (T1DM) mice. In this study, extraction of polysaccharides from selenium-enriched fungus was carried out after 60Co-γ-ray irradi
Externí odkaz:
https://doaj.org/article/92894b0ae03c493fa34e5a8fa0935269
Publikováno v:
Journal of Functional Foods, Vol 122, Iss , Pp 106482- (2024)
This study focused on examining the effects and mechanism of action of ginseng flower alcohol extract (GFAE) on a drug-induced liver injury (DILI) mice model. Ginseng blossoms were extracted with alcohol and examined for their principal active compon
Externí odkaz:
https://doaj.org/article/86f9d2f45da84390bac95bef60b0b802
Autor:
Yazhou Guo, Yang Yuan, Ruibo Wang, Jun Bai, Yanqing Jia, Xinxin Qiu, Huafeng Niu, Long Li, Yan Luo, Baoyu Zhao, Zhencang Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Monocrotaline (MCT), a major pyrrolizidine alkaloid, is well-known for its high liver toxicity. Dysregulation of autophagy induced apoptosis can lead to various liver diseases, including those induced by chemical compounds. Therefore, we aim to explo
Externí odkaz:
https://doaj.org/article/288a197416264b7a980a85195004a3dd
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36175- (2024)
Objective: To examine and talk about the mechanism of the Huoxue Jiegu compound capsule's effects on osteoblasts and the PI3K/Akt/mTOR signal pathway in rabbits suffering from tibial fractures. Method: In vitro, CCK8 was used to assess the survival r
Externí odkaz:
https://doaj.org/article/de3f696ddf0f4ae9bfd1afe396828a64
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e34047- (2024)
Cervical cancer (CC) is a malignant tumor of the female reproductive system that typically occurs in cervical cells and has high incidence and mortality rates, strong metastatic ability, and poor prognosis. Asiatic acid (AA) exhibits anti-inflammator
Externí odkaz:
https://doaj.org/article/179952f4097145a58816ab474d3d6a87
Autor:
Jiang, Bing a, Wang, Yan b, Zhi, Xiaodong a, c, d, Liu, Ai a, Wang, Lingyun a, Wang, Xuehan e, Wang, Zheng a, Duan, Ying f, Li, Yingdong a, c, d, Zhang, Zheng a, g, ⁎
Publikováno v:
In International Immunopharmacology 3 January 2025 145
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background The aim of this study was to investigate the pathogenicity of vancomycin-resistant Enterococcus faecalis (VREs) to human colon cells in vitro. Methods Three E. faecalis isolates (2 VREs and E. faecalis ATCC 29212) were cocultured
Externí odkaz:
https://doaj.org/article/0b4443fa83db4dcfacb232f612a8f611
Publikováno v:
Journal of Functional Foods, Vol 116, Iss , Pp 106083- (2024)
The aim of this study was to investigate the effects and mechanisms of action of extract of Adventitious Root of Ginseng (GARE) on a mouse model of Type 1 diabetes mellitus (T1DM). Firstly, using network pharmacology methods to predict relevant targe
Externí odkaz:
https://doaj.org/article/42f3d6768d854a8d87dee42bc378fd97