Zobrazeno 1 - 10
of 4 254
pro vyhledávání: '"PI3K/AKT signaling"'
Autor:
Xiuping Zhang, Linghui Zhu, Jinchen Ma, Yi Zheng, Xuejing Yang, Lingling Yang, Yang Dong, Yan Zhang, Baoxing Liu, Lingru Li
Publikováno v:
Journal of Traditional Chinese Medical Sciences, Vol 11, Iss 4, Pp 443-455 (2024)
Objective: To provide the mechanism-based pharmacotherapy of the Huatan Qushi formula (HTQS formula), for the health management and treatment of non-alcoholic fatty liver disease (NAFLD). Methods: A rat model of NAFLD was employed to examine the effi
Externí odkaz:
https://doaj.org/article/cc9d036a40e04ead94a6c777d89eb2bc
Autor:
Yuanyuan Zhao, Xiaoqian Wu, Fanyu Meng, Xiaorong Liu, Jingchuan Yuan, Xuhui Zhang, Geng Tian, Xiaohua Wu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder and metabolic abnormality disease that mainly affects women of reproductive age. LINC00173, a novel long noncoding RNA (lncRNA), has emerged as an important factor in the dev
Externí odkaz:
https://doaj.org/article/580a09cb6aa344a99a5f14b7ac3e87a8
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background Endometrial cancer (EC) presents significant clinical challenges due to its heterogeneity and complex pathophysiology. SAMHD1, known for its role as a deoxynucleotide triphosphate triphosphohydrolase, has been implicated in the pr
Externí odkaz:
https://doaj.org/article/6096e829ab914fcfa1afa9eecc8b480a
Publikováno v:
World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Ferroptosis, a non-apoptotic form of regulated cell death, plays a critical role in the suppression of various tumor types, including ovarian cancer. Artesunate (ART), a derivative of artemisinin, exhibits extensive antitumor effe
Externí odkaz:
https://doaj.org/article/e670d90602784dafa9f4d38201478a09
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 4529-4550 (2024)
Min Zhao,1 Liuxiang Feng,2 Wenhua Li3 1School of Medicine, Lijiang University of Culture and Tourism, Lijiang, Yunnan, 674100, People’s Republic of China; 2People’s Hospital of Yulong Naxi Autonomous County of Lijiang City, Lijiang, Yunnan, 67411
Externí odkaz:
https://doaj.org/article/8ea0b0aafb9a4245b0008387e93d9ed7
Publikováno v:
Shipin gongye ke-ji, Vol 45, Iss 20, Pp 369-377 (2024)
Objective: To explore the protective effects of 20-Hydroxyecdysone (20-HE) on high glucose induced HepG2 cells and its related molecular mechanism. Methods: In this study, high glucose (50 mmol/L glucose) was used to establish the oxidative damage mo
Externí odkaz:
https://doaj.org/article/c6a59c7cac334adc8cf9e26502373d80
Autor:
Yue Ma, Yao Zhang, Xizi Jiang, Jingqian Guan, Huanxi Wang, Jiameng Zhang, Yue Tong, Xueshan Qiu, Renyi Zhou
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract KIFC3 is a member of the Kinesin superfamily proteins (KIFs). The role of KIFC3 in non-small cell lung cancer (NSCLC) is unknown. This study aimed to elucidate the function of KIFC3 in NSCLC and the underlying mechanism. Immunohistochemistry
Externí odkaz:
https://doaj.org/article/d01cfceeba8a4215bbce61500b049d79
Publikováno v:
International Journal of COPD, Vol Volume 19, Pp 1819-1834 (2024)
Haidong He,1 Shuihua Sun,2 Weihua Xu,1 Mingwan Zhang3 1Department of Pulmonary and Critical Care Medicine, Tongde Hospital of Zhejiang Province, Hangzhou City, Zhejiang Province, People’s Republic of China; 2Department of Medical Oncology, Tongde H
Externí odkaz:
https://doaj.org/article/6f500d2ad26441c0a8603302eff0f90e
Autor:
Yue Xue, Xiu Cheng, Zhang-Qiang Ma, Hou-Peng Wang, Chong Zhou, Jia Li, Da-Lei Zhang, Liao-Liao Hu, Yan-Fan Cui, Jian Huang, Tao Luo, Li-Ping Zheng
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Nanoplastics (NPs) are emerging pollutants that pose risks to living organisms. Recent findings have unveiled the reproductive harm caused by polystyrene nanoparticles (PS-NPs) in female animals, yet the intricate mechanism remain
Externí odkaz:
https://doaj.org/article/1f837b31f0404ff3a42f705a2870310a
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Background Colorectal cancer (CRC) is a prevalent malignancy with high morbidity and mortality rates. Previous studies have demonstrated that interleukin (IL)-22 is involved in CRC progression; however, the exact mechanism remains unclear. T
Externí odkaz:
https://doaj.org/article/1ec3470951c443e6941ca6e9878f69ad