Výsledky vyhledávání - "PHOTORECEPTOR TRANSDUCTION"

Akademický článek

An unexpected INAD PDZ tandem-mediated plcβ binding in Drosophila photo receptors

Autor: Fei Ye, Yuxin Huang, Jianchao Li, Yuqian Ma, Chensu Xie, Zexu Liu, Xiaoying Deng, Jun Wan, Tian Xue, Wei Liu, Mingjie Zhang

Publikováno v: eLife, Vol 7 (2018)

INAD assembles key enzymes of the Drosophila compound eye photo-transduction pathway into a supramolecular complex, supporting efficient and fast light signaling. However, the molecular mechanism that governs the interaction between INAD and NORPA (p

Externí odkaz: https://doaj.org/article/5fa428b201cd4c9ebae3efafe1ea2150

Zobrazit plný text záznamu

Akademický článek

Microsaccadic sampling of moving image information provides Drosophila hyperacute vision

Autor: Mikko Juusola, An Dau, Zhuoyi Song, Narendra Solanki, Diana Rien, David Jaciuch, Sidhartha Anil Dongre, Florence Blanchard, Gonzalo G de Polavieja, Roger C Hardie, Jouni Takalo

Publikováno v: eLife, Vol 6 (2017)

Small fly eyes should not see fine image details. Because flies exhibit saccadic visual behaviors and their compound eyes have relatively few ommatidia (sampling points), their photoreceptors would be expected to generate blurry and coarse retinal im

Externí odkaz: https://doaj.org/article/723554c067f744979d9da6f89f9c889f

Zobrazit plný text záznamu

Avian Adeno-Associated Viral Transduction of the Postembryonic Chicken Retina

Autor: William K. Stell, Frank Visser, Andy J. Fischer, Derek Waldner, N. Torben Bech-Hansen

Publikováno v: Translational Vision Science & Technology

Purpose The posthatching chicken is a valuable animal model for research, but molecular tools needed for altering its gene expression are not yet available. Our purpose here was to adapt the adeno-associated viral (AAV) vector method, used widely in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55dd28a18ef34cd1abeb329b5f8cca1
https://pubmed.ncbi.nlm.nih.gov/31293820

Zobrazit plný text záznamu

Impact of vital dyes on cell viability and transduction efficiency of AAV vectors used in retinal gene therapy surgery: an in vitro and in vivo analysis

Autor: Anna Paola Salvetti, Robert E MacLaren, Alun R. Barnard, Maria I. Patrício, Doron G. Hickey, Harry O Orlans

Publikováno v: Translational Vision Science & Technology

PURPOSE: Treatment of inherited retinal degenerations using adeno-associated viral (AAV) vectors involves delivery by subretinal injection. In the latter stages, alteration of normal anatomy may cause difficulty in visualizing the retinotomy, retinal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbcd3e4381752d92c4e6d47e4039a82c
http://ora.ox.ac.uk/objects/uuid:

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Kniha

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

The positive role of the carboxyl terminus of the γ subunit of retinal cGMP-phosphodiesterase in maintaining phosphodiesterase activity in vivo

Autor: Chyuan-Sheng Lin, Clyde K. Yamashita, Debora B. Farber, Stephen H. Tsang, Peter Gouras, Stephen P. Goff, Won Ho Lee

Publikováno v: Vision Research. 42(4):439-445

The inhibitory rod cyclic GMP-phosphodiesterase gamma subunit, PDEgamma, is a key component of the photoresponse and is required to support rod integrity. Pdeg(tm1)/Pdeg(tm1) mice that lack PDEgamma due to a targeted disruption of the gene encoding P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d829d874ea9055728e109609efa782

Zobrazit plný text záznamu

AAV-mediated photoreceptor transduction of the pig cone-enriched retina

Autor: Edoardo Villani, Massimo Giunti, Roberto Giovannoni, Marialuisa Lavitrano, Alberto Auricchio, Francesco Viola, Enrico Maria Surace, U. Di Vicino, Settimio Rossi, Roberto Ratiglia, Elena Marrocco, Francesca Simonelli, Francesco Testa, Maria Laura Bacci, M. Della Corte, M. Crasta, Monica Doria, Claudio Mussolino, Simona Neglia

Publikováno v: Gene Therapy
Gene Therapy; Vol 18

Recent success in clinical trials supports the use of adeno-associated viral (AAV) vectors for gene therapy of retinal diseases caused by defects in the retinal pigment epithelium (RPE). In contrast, evidence of the efficacy of AAV-mediated gene tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a089501c56937addf4cf7a303dcf424e
http://hdl.handle.net/11585/103209

Zobrazit plný text záznamu

Gene Delivery to the Pig Cone-Enriched Retina Highlights Species-Specific Differences in AAV-Mediated Photoreceptor Transduction

Autor: Mussolino C., Viola F., Della Corte M., Rossi S., Di Vicino U., Neglia S., Doria M., Testa F., Giovannoni G., Crasta M., Villani E., Lavitrano M., Ratiglia R., Simonelli F., Auricchio A., Surace E. M., GIUNTI, MASSIMO, BACCI, MARIA LAURA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4094::aecab5ff8312c9b0658d7a359dda0194
http://hdl.handle.net/11585/91167

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Vyhledávací nástroje:

Upřesnit hledání