Zobrazeno 1 - 10
of 3 699
pro vyhledávání: '"PH REGULATION"'
Autor:
Christine Rascle, Bastien Malbert, Isabelle Goncalves, Mathias Choquer, Christophe Bruel, Nathalie Poussereau
Publikováno v:
BMC Genomic Data, Vol 25, Iss 1, Pp 1-3 (2024)
Abstract Objectives Botrytis cinerea, the causal agent of gray mold, is a necrotrophic fungus that can infect a wide variety of plant species and plant tissues. During infection, this pathogen modulates the pH of its environment by secreting organic
Externí odkaz:
https://doaj.org/article/8b2caacc3ccc47c6b2106442a26fe5fc
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Metabolic acidosis (MAc)—an extracellular pH (pHo) decrease caused by a [HCO3−]o decrease at constant [CO2]o—usually causes intracellular pH (pHi) to fall. Here we determine the extent to which the pHi decrease depends on the pHo decrease vs th
Externí odkaz:
https://doaj.org/article/2a62928045b4444992ceda97ed66d00a
Autor:
João Francisco Pollo Gaspary, Lee Edgar, Luis Felipe Dias Lopes, Carmen Brum Rosa, Julio Cezar Mairesse Siluk
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
BackgroundCarbon dioxide (CO2), traditionally viewed as a mere byproduct of cellular respiration, plays a multifaceted role in human physiology beyond simple elimination through respiration. CO2 may regulate the tumor microenvironment by significantl
Externí odkaz:
https://doaj.org/article/2201c24882774b61a274fc8dee4f7881
Autor:
Kun Huang, Qinqin Wang, Huilong Qu, Xinyu Hu, Wenhao Niu, Anna Hultgårdh-Nilsson, Jan Nilsson, Chun Liang, Yihong Chen
Publikováno v:
Regenerative Therapy, Vol 25, Iss , Pp 331-343 (2024)
Based on disappointing results of stem cell-based application in clinical trials for patients with critical limb ischemia, we hypothesized that the acidic environment might be the key factor limiting cell survival and function. In the present study,
Externí odkaz:
https://doaj.org/article/06b363a6fa97408ab4b1f3da998ef66f
Autor:
Yue Yao, Yi Xu, Liang Yu, Ting‐Mao Xue, Zhi‐Jie Xiao, Pui‐Chi Tin, Hiu‐Ling Fung, Hoi‐Tang Ma, Jing‐Ping Yun, Judy Wai Ping Yam
Publikováno v:
Cancer Communications, Vol 44, Iss 2, Pp 251-272 (2024)
Abstract Background Small extracellular vesicles (sEVs) mediate intercellular communication that contributes to hepatocellular carcinoma (HCC) progression via multifaceted pathways. The success of cell entry determines the effect of sEV on recipient
Externí odkaz:
https://doaj.org/article/b2e9a3c31e724dc38e92fd0ac8e57e35
Autor:
Elena Gantsova, Oxana Serova, Polina Vishnyakova, Igor Deyev, Andrey Elchaninov, Timur Fatkhudinov
Publikováno v:
PeerJ, Vol 12, p e17316 (2024)
This review discusses the importance of homeostasis with a particular emphasis on the acid-base (AB) balance, a crucial aspect of pH regulation in living systems. Two primary organ systems correct deviations from the standard pH balance: the respirat
Externí odkaz:
https://doaj.org/article/d7a897c78c044fbda336be62bef6159a
Autor:
Reo Hamaguchi, Masahide Isowa, Ryoko Narui, Hiromasa Morikawa, Toshihiro Okamoto, Hiromi Wada
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2197 (2024)
This review article investigates the relationship between mitochondrial dysfunction and cancer progression, emphasizing the metabolic shifts that promote tumor growth. Mitochondria are crucial for cellular energy production, but they also play a sign
Externí odkaz:
https://doaj.org/article/d09c2d9c1650487cb766c6e7fbcaa19e
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 685 (2024)
pH homeostasis is crucial for spermatogenesis, sperm maturation, sperm physiological function, and fertilization in mammals. HCO3− and H+ are the most significant factors involved in regulating pH homeostasis in the male reproductive system. Multip
Externí odkaz:
https://doaj.org/article/c32d01b6ab8346d0ba56c9a6d9e04a4a
Autor:
Huan Wang, Shuting Zhao, Zexin Qi, Changgang Yang, Dan Ding, Binbin Xiao, Shihong Wang, Chunwu Yang
Publikováno v:
Plants, Vol 13, Iss 9, p 1227 (2024)
Soil alkalization is an important environmental factor limiting crop production. Despite the importance of root secretion in the response of plants to alkali stress, the regulatory mechanism is unclear. In this study, we applied a widely targeted met
Externí odkaz:
https://doaj.org/article/3215a1839ddb459e85ecc55c5a5090d7
Autor:
Claudiu T. Supuran
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
While the carbonic anhydrase (CA, EC 4.2.1.1) superfamily of enzymes has been described primarily as involved only in pH regulation for decades, it also has many other important functions. CO2, bicarbonate, and protons, the physiological substrates o
Externí odkaz:
https://doaj.org/article/26b700862adf4b9e8a9f439993c98ba1