Zobrazeno 1 - 10
of 1 521
pro vyhledávání: '"PGC-1{alpha}"'
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Throughout our evolutionary history, physical activity has played a significant role in shaping our physiology. Advances in exercise science have further reinforced this concept by highlighting how exercise can change gene expression and molecular si
Externí odkaz:
https://doaj.org/article/b04befb5c54849ca82db462a605004ee
Autor:
Jutrić David, Đikić Domagoj, Boroš Almoš, Odeh Dyna, Drozdek Sandra Domjanić, Gračan Romana, Dragičević Petar, Crnić Irena, Jurčević Irena Landeka
Publikováno v:
Arhiv za Higijenu Rada i Toksikologiju, Vol 73, Iss 1, Pp 71-82 (2022)
Valproate is a common antiepileptic drug whose adverse effects include liver steatosis and dyslipidaemia. The aim of our study was to see how natural flavonoid antioxidant naringin would interact with valproate and attenuate these adverse effects. Fo
Externí odkaz:
https://doaj.org/article/98b75cb64fab4e52ba0c7622aecbc1e7
Akademický článek
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Publikováno v:
Diabetes, Metabolic Syndrome and Obesity, Vol Volume 13, Pp 4041-4049 (2020)
Ning Zhu, Xue Yan, Hongli Li, Huiqin Wang Department 1 of Cardiology, Baoding First Center Hospital, Baoding 071002, Hebei, People’s Republic of ChinaCorrespondence: Ning ZhuDepartment 1 of Cardiology, Baoding First Center Hospital, 320 Changchengb
Externí odkaz:
https://doaj.org/article/953b4a5c5b0445b49a86c06fe37ca2c7
Autor:
Qian Zhang, Wei Song, Bingjia Zhao, Jun Xie, Qing Sun, Xiaohu Shi, Bin Yan, Guoqing Tian, Xiaochun Liang
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The AMPK/PGC-1α pathway-mediated mitochondrial dysfunction has been supposed to play a crucial role in pathogenesis of diabetic peripheral neuropathy (DPN). The present study investigated the neuroprotective potential of quercetin, a natural AMPK ac
Externí odkaz:
https://doaj.org/article/dee3b7a44c814c4b8bf223ca65d6b9bd
Autor:
Anna Wilkaniec, Anna M. Lenkiewicz, Lidia Babiec, Emilia Murawska, Henryk M. Jęśko, Magdalena Cieślik, Carsten Culmsee, Agata Adamczyk
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Aberrant secretion and accumulation of α-synuclein (α-Syn) as well as the loss of parkin function are associated with the pathogenesis of Parkinson’s disease (PD). Our previous study suggested a functional interaction between those two proteins,
Externí odkaz:
https://doaj.org/article/7c827104395b46819f287f33340f635d
Autor:
Alexander J. Watts, Samantha M. Logan, Anna Kübber-Heiss, Annika Posautz, Gabrielle Stalder, Johanna Painer, Kristina Gasch, Sylvain Giroud, Kenneth B. Storey
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Differential levels of n-6 and n-3 essential polyunsaturated fatty acids (PUFAs) are incorporated into the hibernator’s diet in the fall season preceding prolonged, multi-days bouts of torpor, known as hibernation. Peroxisome proliferator-activated
Externí odkaz:
https://doaj.org/article/322e78f4e8f0406cba61738f86ff3c7d
Autor:
Eman F. Wasfey, Rania S. Abd El-Razik, Nadia H. Hamdy, Wael M. El-Kilany, Hala O. El-Mesallamy
Publikováno v:
Archives of Pharmaceutical Sciences Ain Shams University, Vol 2, Iss 1, Pp 16-21 (2018)
Accumulating evidence suggests that molecular alterations of peripheral leucocytes are possible diagnostic markers of acute myocardial infarction (AMI). Changed lipid/glucose metabolism is a prominent feature of the pathogenesis of AMI. Silent mating
Externí odkaz:
https://doaj.org/article/0b3c109663fa4df4b5eb5ae9f1f60eba
Autor:
Maximilian Pohland, Maren Pellowska, Heike Asseburg, Stephanie Hagl, Martina Reutzel, Aljoscha Joppe, Dirk Berressem, Schamim H. Eckert, Mario Wurglics, Manfred Schubert‐Zsilavecz, Gunter P. Eckert
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2018)
Abstract Background Current approved drugs for Alzheimer’s disease (AD) only attenuate symptoms, but do not cure the disease. The pirinixic acid derivate MH84 has been characterized as a dual gamma-secretase/proliferator activated receptor gamma (P
Externí odkaz:
https://doaj.org/article/d3adf72618f74d0eb45cc6102776126a
Akademický článek
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